5 recruiting, 1 active not recruiting, 1 completed, 1 not yet recruiting. 2 Not applicable, 2 Phase 4, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Not yet recruiting 1, Recruiting 1 |
| Phase 4 | 2 | Recruiting 2 |
| Phase 2 | 1 | Active not recruiting 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Heart Failure With Mildly Reduced Ejection Fraction: new trials by email Literature Review of Heart Failure With Mildly Reduced Ejection Fraction trials Research Report on Heart Failure With Mildly Reduced Ejection Fraction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pharmacological Optimization in Prevention in Heart Failure: A Sex-gap? Guideline-Directed Medical Therapy (GDMT) - Heart Failure, Acute Heart Failure | Phase 4 | Recruiting | IRCCS Policlinico S. Donato | 368 | 2026-03-31 | 2026-10-16 |
| A Study to Evaluate the Safety and Efficacy of NT-88 Conventional therapeutic drugs, NT-88 - Heart Failure With Mildly Reduced Ejection Fraction | Not applicable | Not yet recruiting | Guangzhou Manjing biomedicine technology co., ltd | 60 | 2026-03-30 | 2026-04-03 |
| Treating Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction: Ablation or Medication Catheter Ablation for Atrial Fibrillation, Rate Control Medications (beta-blockers, calcium channel blockers, digoxin) - Atrial Fibrillation (AF), Heart Failure With Mildly Reduced Ejection Fraction | Not applicable | Recruiting | Nova Scotia Health Authority | 84 | 2026-01-01 | 2026-10-20 |
| Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity Maridebart cafraglutide, Placebo - Heart Failure With Preserved Ejection Fraction, Heart Failure With Mildly Reduced Ejection Fraction | Phase 3 | Recruiting | Amgen | 5056 | 2025-06-25 | 2026-09-16 |
| A Study of IBI362 in Subjects With HFpEF or HFmrEF Combined With Obesity placebo, IBI362 - Obesity, Heart Failure With Preserved Ejection Fraction (HFPEF) | Phase 2 | Active not recruiting | Innovent Biologics (Suzhou) Co. Ltd. | 141 | 2025-03-26 | 2026-09-22 |
| Iron Deficiency in Patients With Heart Failure and Reduced and Mildly Reduced Ejection Fraction Iron Deficiency, Heart Failure With Reduced Ejection Fraction | Completed | Jordan Collaborating Cardiology Group | 450 | 2023-09-01 | 2025-02-25 | |
| PBMC as Biomarkers of Diabetic Cardiomyopathy Blood test, quality of life Questionnaire, Diet habits questionnaire - Type 2 Diabetes, Metabolic Syndrome | Recruiting | Hospices Civils de Lyon | 175 | 2023-05-23 | 2026-03-27 | |
| CAtheter-Based Ablation of Atrial Fibrillation Compared to Conventional Treatment in Patients With Heart Failure With Preserved Ejection Fraction CE-marked Catheter Ablation - Atrial Fibrillation, Heart Failure With Preserved Ejection Fraction | Phase 4 | Recruiting | Charite University, Berlin, Germany | 1548 | 2023-03-01 | 2023-03-06 |
Heart Failure (4) · Atrial Fibrillation (2) · Obesity (2) · Diabetes Mellitus, Type 2 (1) · Iron Deficiencies (1) · Metabolic Syndrome (1)
Cardiovascular Diseases (5) · Heart Diseases (5) · Nutritional and Metabolic Diseases (4) · Pathological Conditions, Signs and Symptoms (4) · Arrhythmias, Cardiac (2) · Body Weight (2) · Metabolic Diseases (2) · Nutrition Disorders (2) · Overnutrition (2) · Overweight (2) · Pathologic Processes (2) · Signs and Symptoms (2) · Diabetes Mellitus (1) · Endocrine System Diseases (1) · Glucose Metabolism Disorders (1)
Adrenergic beta-Antagonists (1) · Calcium Channel Blockers (1) · Catheter Ablation (1) · Digoxin (1) · Hematologic Tests (1) · mazdutide (1)
Amgen (1) · Charite University, Berlin, Germany (1) · Guangzhou Manjing biomedicine technology co., ltd (1) · Hospices Civils de Lyon (1) · IRCCS Policlinico S. Donato (1) · Innovent Biologics (Suzhou) Co. Ltd. (1) · Jordan Collaborating Cardiology Group (1) · Nova Scotia Health Authority (1)
Canada (2) · China (2) · France (2) · Germany (2) · Italy (2) · Argentina (1) · Australia (1) · Austria (1) · Belgium (1) · Brazil (1) · Bulgaria (1) · Chile (1) · Colombia (1) · Czechia (1) · Denmark (1)
Abdul Parwani, Dr. (1) · Burkert Pieske, Prof. Dr. (1) · Paulus Kirchhof, Prof. Dr. (1) · Ramzi Tabbalat (1) · Roland Tilz, Prof. Dr. (1) · Tim Friede, Prof. Dr. (1)
2025 (1)