4 completed, 3 enrolling by invitation, 3 recruiting, 2 active not recruiting. 11 Not applicable, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 3, Enrolling by invitation 3, Recruiting 3, Active not recruiting 1, Not yet recruiting 1 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
| Phase 1 | 1 | Active not recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Womens Health Screening and the Oral Microbiome Listerine mouthrinse - Oral Health, Menopause | Not yet recruiting | University of Plymouth | 240 | 2026-10-01 | 2026-10-06 | |
| Effectiveness of Personalized Oral Hygiene Advice Delivered by Artificial Intelligence or Dental Professionals Versus Standard Oral Hygiene Advice on Oral and Systemic Health in Community-based Type II Diabetes Patients AI OHI group, Human-OHI group, Control group - Gum Disease, Diabetes | Not applicable | Not yet recruiting | The University of Hong Kong | 105 | 2026-10-01 | 2026-10-01 |
| CHEER Oral Health in Pregnancy Study Enhanced Care, Enhanced Care + - Gingivitis, Dental Health | Not applicable | Recruiting | University of California, San Francisco | 160 | 2026-09-29 | 2026-10-08 |
| Impact of an Arginine-containing Toothpaste on the Subgingival Microbiota in Patients in Supportive Periodontal Care Arginine Toothpaste, Fluoride Toothpaste - Gum Disease | Not applicable | Enrolling by invitation | Sukirth M Ganesan, BDS, PhD | 108 | 2026-08-05 | 2026-09-10 |
| Immediate Implant Provisionalization Dental implant placement - Gum Disease | Not applicable | Enrolling by invitation | University of Michigan | 44 | 2026-06-19 | 2026-10-06 |
| Improving Oral and Systemic Health in Individuals With Prediabetes Through Personalized Oral Hygiene Advice Provided by Dentists or by AI AI OHI group, Dental professionals OHI group - Gum Disease, Prediabetes | Not applicable | Recruiting | The University of Hong Kong | 148 | 2025-04-12 | 2025-12-03 |
| An Evaluation of the Effect of the Erchonia FX-405 Laser as an Adjunctive Treatment of Periodontitis Erchonia® FX405, Placebo Laser - Periodontal Diseases, Periodontitis | Not applicable | Recruiting | Erchonia Corporation | 70 | 2025-01-01 | 2026-05-18 |
| Influence of Implant Crown Transmucosal Contour Design on Soft and Hard Tissue Clinical Outcomes Implant crown delivery - Gum Disease | Not applicable | Enrolling by invitation | University of Michigan | 30 | 2023-11-28 | 2026-08-12 |
| Efficacy of Devices in Maintaining Oral Health and Managing Periodontal and Interproximal Tissues Group 1: use of the rubber interdental brush (picks) at baseline for 3 months, Group 2: use of the traditional bristle interdental brush at baseline for 3 months - Gingivitis, Gum Disease | Not applicable | Active not recruiting | University of Roma La Sapienza | 40 | 2023-09-01 | 2026-04-22 |
| Randomized Clinical Trial: Oral Health Package Law and Fluor Varnish Impact on Schoolchildren in Merida, Mexico Fluoride varnish, Fluoride toothpaste - Caries, Gum Disease | Phase 3 | Unknown | Anahuac Mayab University | 900 | 2023-06-22 | 2023-07-25 |
| A New Mouthwash on Reducing Dental Plaque and Helping Prevent Gum Problems 0.2% zinc lactate, 0.17% amine fluoride and 0.0275% sodium fluoride Mouthwash, 0.057% sodium fluoride Mouthwash - Plaque, Gum Disease | Phase 3 | Completed | Colgate Palmolive | 80 | 2021-03-08 | 2023-04-20 |
| Periodontal Treatment and Psychology Psychological measurements - Gum Disease | Not applicable | Completed | Ozge Gokturk | 184 | 2015-05-04 | 2017-06-16 |
| Dental Plaque Removal Study Manual Toothbrush only, MTB + Waterpik Ultra Water Flosser 'High', MTB + Floss (MTB+Floss) - Gingivitis, Gum Disease | Not applicable | Completed | University of North Carolina, Chapel Hill | 270 | 2012-02-01 | 2018-08-31 |
| The Use of Functional Confections in Promoting Oral Health Strawberry gummy, Placebo control gummy - Oral Health, Oral Cancer | Phase 1 | Active not recruiting | Ohio State University | 36 | 2010-11-01 | 2025-10-20 |
| Efficacy of New Alcohol Free Mouthrinses alcohol-free experimental mouth rinse, alcohol-containing mouth rinsing - Gum Disease | Not applicable | Completed | University of Witten/Herdecke | 160 | 2010-02-01 | 2013-03-14 |
Gingival Diseases (15) · Gingivitis (3) · Periodontal Diseases (3) · Depression (1) · Diabetes Mellitus (1) · Mouth Neoplasms (1) · Periodontitis (1) · Plaque, Amyloid (1) · Prediabetic State (1)
Mouth Diseases (15) · Stomatognathic Diseases (15) · Periodontal Diseases (12) · Infections (3) · Endocrine System Diseases (2) · Glucose Metabolism Disorders (2) · Metabolic Diseases (2) · Nutritional and Metabolic Diseases (2) · Behavior (1) · Behavioral Symptoms (1) · Diabetes Mellitus (1) · Head and Neck Neoplasms (1) · Neoplasms (1) · Neoplasms by Site (1) · Pathological Conditions, Anatomical (1)
Control Groups (1) · Ethanol (1)
The University of Hong Kong (2) · University of Michigan (2) · Anahuac Mayab University (1) · Colgate Palmolive (1) · Erchonia Corporation (1) · Ohio State University (1) · Ozge Gokturk (1) · Sukirth M Ganesan, BDS, PhD (1) · University of California, San Francisco (1) · University of North Carolina, Chapel Hill (1) · University of Plymouth (1) · University of Roma La Sapienza (1) · University of Witten/Herdecke (1)
United States (7) · Italy (2) · Germany (1) · Hong Kong (1) · Mexico (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Walter Y.H. Lam, Prof. (2) · Effie Ioannidou, DDS, MDS (1) · Hom-Lay Wang, DDS MSD PhD (1) · Laura Jelliffe-Pawlowski, PhD (1) · Luigi Montesani, MD, DDS (1) · Muhammad Saleh, BDS, MSD (1) · Ozge Gokturk (1) · Stefan Zimmer, Professor (1) · Steven Offenbacher, DDS, PhD, MMSc (1) · Sukirth Ganesan, BDS,PhD,MPH (1) · Yael Vodovotz, PhD. (1)