16 completed, 7 unknown, 2 not yet recruiting, 1 recruiting. 13 Not applicable, 5 Phase 4, 2 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 13 | Completed 7, Unknown 3, Not yet recruiting 1, Recruiting 1, Terminated 1 |
| Phase 4 | 5 | Completed 4, Not yet recruiting 1 |
| Phase 1 | 2 | Completed 2 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
Follow Glaucoma, Primary Open Angle: new trials by email Literature Review of Glaucoma, Primary Open Angle trials Research Report on Glaucoma, Primary Open Angle
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Lumify™ on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma Patients brimonidine tartrate ophthalmic solution 0.025%, sterile balanced saline solution - Glaucoma, Glaucoma, Open-Angle | Phase 4 | Not yet recruiting | Tulane University | 60 | 2027-11-01 | 2026-10-13 |
| Evaluation the Safety and Effectiveness of the GORE GDI in Adult Subjects With Primary Open-angle Glaucoma in Whom Previous Medical and Surgical Treatment Have Failed. GORE Glaucoma Drainage Implant - Glaucoma, Primary Open Angle | Not applicable | Not yet recruiting | Gore Ophthalmic | 70 | 2026-10-01 | 2026-10-19 |
| Treating Psychosocial Distress in Glaucoma Acceptance commitment therapy - Glaucoma, Primary Open Angle, Distress, Emotional | Not applicable | Completed | Duke University | 28 | 2025-04-01 | 2026-03-18 |
| Safety and Feasibility of the ELIOS System in POAG Patients ELIOS Procedure - Glaucoma, Primary Open Angle | Not applicable | Completed | Elios Vision, Inc. | 22 | 2023-10-18 | 2026-06-16 |
| Effect of Peripapillary Atrophy to Diagnose Glaucoma in High Myopia OCT imaging - Myopia, Refractive Errors | Unknown | Zhongshan Ophthalmic Center, Sun Yat-sen University | 120 | 2023-08-01 | 2023-07-28 | |
| Glaucoma Assessment Via Reading Ability C-Read test - Glaucoma, Primary Open Angle | Unknown | Peking University | 200 | 2023-01-01 | 2023-01-06 | |
| Evaluation of Nanodropper-mediated Microdrops vs. Standard Drops of 0.5% Timolol Maleate in Glaucoma Patients Nanodropper adaptor, Original eyedrop bottle/No Nanodropper - Glaucoma, Glaucoma, Open-Angle | Not applicable | Completed | Nanodropper, Inc. | 420 | 2021-11-06 | 2023-01-18 |
| Excimer Laser Trabeculostomy Glaucoma Treatment Study ELIOS Procedure - Glaucoma, Primary Open Angle | Not applicable | Completed | Elios Vision, Inc. | 318 | 2021-05-10 | 2026-06-16 |
| The Effect of Topical Brimonidine on the Ocular Hemodynamics in Patients of POAG Using OCTA Brimonidine tartrate 0.2% ophthalmic solution - Glaucoma, Primary Open Angle, Ocular Blood Flow | Phase 4 | Completed | Fayoum University | 41 | 2020-05-01 | 2022-07-26 |
| Investigate, Following Cataract Surgery With IOL in Conjunction With Intracanalicular Dexamethasone Insert Intracanalicular Dexamethasone, 0.4 mg insert - Glaucoma, Primary Open Angle, Cataract | Phase 4 | Completed | Wolstan and Goldberg Eye Associates | 40 | 2020-02-10 | 2022-08-22 |
| Safety and IOP-Lowering Effects of WB007 WB007 0.05%, WB007 0.15%, WB007 0.4% - Glaucoma, Primary Open Angle, Ocular Hypertension | Phase 1 / Phase 2 | Completed | Bausch & Lomb Incorporated | 77 | 2019-11-14 | 2025-03-27 |
| Caffeine Consumption in Glaucoma Patients and Healthy Subjects Caffeine tablet - Glaucoma, Primary Open Angle | Not applicable | Completed | Wills Eye | 18 | 2018-12-30 | 2026-10-13 |
| UCP (Ultrasound Cyclo Plasty) in the Treatment of Chinese Patients With Primary Open-angle Glaucoma ultrasound cyclo plasty - Glaucoma, Glaucoma, Primary Open Angle | Not applicable | Unknown | Zhongshan Ophthalmic Center, Sun Yat-sen University | 60 | 2018-08-12 | 2020-03-25 |
| Prospective, Single Center Switching Study of 0.0015% Tafluprost Ophthalmic Solution in Primary Open-angle Glaucoma and Ocular Hypertension Patients With Corneal Disorders (Switching From 0.005% Latanoprost Ophthalmic Solution) Latanoprost, tafluprost - Glaucoma, Primary Open Angle | Not applicable | Completed | Santen Pharmaceutical (Taiwan) Co., LTD | 1 | 2018-04-02 | 2021-02-04 |
| Adaptive Optics Retinal Imaging oxygen inhalation, Adaptive optics imaging - Glaucoma, Primary Open Angle | Not applicable | Recruiting | Food and Drug Administration (FDA) | 150 | 2018-01-22 | 2026-05-08 |
| Exploratory Trial to Evaluate the Efficacy and Safety of D565H Twice Daily Versus D565 Once Daily D565H(Latanoprost 25㎍/㎖), D565(Latanoprost 50㎍/㎖) - Glaucoma, Primary Open Angle, Ocular Hypertension | Phase 2 | Unknown | Chong Kun Dang Pharmaceutical | 98 | 2017-03-30 | 2017-07-21 |
| LSFG in Patients With Normal Tension Glaucoma Tension Glaucoma Laser Speckle Flowgraphy - Glaucoma, Primary Open Angle | Not applicable | Unknown | Augenabteilung Allgemeines Krankenhaus Linz | 40 | 2017-01-01 | 2017-10-24 |
| Generic Travoprost Versus Brand Name Travoprost in Patients With Primary Open Angle Glaucoma or Ocular Hypertension Brand name travoprost, Generic travoprost - Glaucoma, Primary Open Angle, Ocular Hypertension | Phase 4 | Completed | Université de Sherbrooke | 76 | 2016-07-01 | 2020-12-01 |
| Evaluation of Safety and Efficacy of TUG (Therapeutic Ultrasound for Glaucoma) in the Treatment of Primary Open Angle Glaucoma or Ocular Hypertension TUG, Sham - Glaucoma, Primary Open Angle, Ocular Hypertension | Not applicable | Terminated | EyeSonix | 25 | 2016-07-01 | 2022-04-06 |
| Longitudinal Study on Glaucoma Surgery Using XEN® Gel Stent XEN® Gel Stent implantation - Glaucoma, Glaucoma, Open-Angle | Not applicable | Unknown | Swiss Vision Network | 150 | 2015-01-01 | 2022-05-05 |
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Glaucoma, Open-Angle (27) · Ocular Hypertension (9) · Glaucoma (5) · Anxiety Disorders (1) · Blepharoptosis (1) · Cataract (1) · Depression (1) · Exfoliation Syndrome (1) · Eye Diseases (1) · Glaucoma, Angle-Closure (1) · Myopia (1) · Refractive Errors (1)
Eye Diseases (26) · Glaucoma (22) · Ocular Hypertension (18) · Behavior (1) · Behavioral Symptoms (1) · Eyelid Diseases (1) · Iris Diseases (1) · Lens Diseases (1) · Mental Disorders (1) · Uveal Diseases (1)
Brimonidine Tartrate (2) · Acceptance and Commitment Therapy (1) · Caffeine (1) · Drug Implants (1) · Latanoprost (1) · Mutagenesis, Insertional (1) · Ophthalmic Solutions (1) · Oxygen Inhalation Therapy (1) · Phacoemulsification (1) · Timolol (1) · Travoprost (1) · tafluprost (1)
Allergan (4) · Elios Vision, Inc. (2) · Zhongshan Ophthalmic Center, Sun Yat-sen University (2) · Augenabteilung Allgemeines Krankenhaus Linz (1) · Bausch & Lomb Incorporated (1) · Chong Kun Dang Pharmaceutical (1) · Duke University (1) · EyeSonix (1) · Fayoum University (1) · Food and Drug Administration (FDA) (1) · Fundación Oftalmológica Nacional (1) · Gore Ophthalmic (1) · Jeffrey L Goldberg (1) · Military Institute od Medicine National Research Institute (1) · Nanodropper, Inc. (1)
United States (9) · Canada (2) · China (2) · Germany (2) · Taiwan (2) · Austria (1) · Colombia (1) · Egypt (1) · India (1) · South Korea (1)
Damien Goldberg, MD (1) · Daniel X Hammer, Ph.D. (1) · David Wirta, MD (1) · Jeffrey L Goldberg, MD, PhD (1) · Jennifer Steger, PhD (1) · Jian Ge, M.D,Ph.D (1) · KiHo Park (1) · M. Reza Razeghinejad, MD (1) · Marjorie Carbonneau, MD, FRCS(C) (1) · Sandra Belalcazar, MD (1) · Ze Zhang, MD (1)
PMID 20552258, PMID 27633513, PMID 30095603, PMID 30615699, PMID 31453000, PMID 32341321, PMID 32551400, PMID 33168747, PMID 33760041, PMID 34605879, PMID 35174258, PMID 42710625
2016 (1), R00EY033027 (1)