23 completed, 12 unknown, 9 recruiting, 4 active not recruiting. 32 Not applicable, 6 Phase 4, 3 Phase 2, 3 Phase 3, 2 Phase 1.
Follow Genitourinary Syndrome of Menopause: new trials by email Literature Review of Genitourinary Syndrome of Menopause trials Research Report on Genitourinary Syndrome of Menopause
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Determining the Extent of the Genitourinary Syndrome of Menopause Burden in Breast Cancer Survivors Questionnaires (NRS, DASS-21, EORTC QLQ-C30, EORTC QLQ-BR42, FSFI, FSDS-R) - Genitourinary Syndrome of Menopause (GSM), Breast Cancer | Recruiting | Jessa Hospital | 264 | 2026-03-05 | 2026-05-04 | |
| Er:YAG Laser Combined With Vaginal Estriol for Genitourinary Syndrome of Menopause Topical estrogen therapy based on estriol (E3), Active Er:YAG Laser, Sham Er:YAG laser (minimal fluence) - Genitourinary Syndrome of Menopause | Not applicable | Recruiting | University of Nove de Julho | 60 | 2025-12-10 | 2026-04-23 |
| Impact of Oral Supplementation With Bioactive Collagen Peptides and Other Functional Ingredients Collagendep - Genitourinary Syndrome of Menopause | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 43 | 2025-09-01 | 2025-09-03 | |
| Effectiveness of a Telerehabilitation Program for Improving Sexual Function and Reducing Pain in Menopausal Women Pelvify: Menopause and dyspareunia treatment, Face to Face Physical Therapy Protocol, Face to Face Protocol Combined With an Asynchronous Telerehabilitation Program - Menopause, Genitourinary Syndrome of Menopause | Not applicable | Recruiting | Instituto Médico Tecnológico SL | 90 | 2025-05-05 | 2025-05-23 |
| Intravaginal Negative Pressure Medical Device for Treatment of Genitourinary Syndrome of Menopause (GSM) Sham (No Treatment) - Genitourinary Syndrome of Menopause | Not applicable | Not yet recruiting | AVeta Medical | 60 | 2025-03-03 | 2025-01-10 |
| Difference in Serum Estrogen Level Based on Methods of Vaginal Estrogen Application (fingertip Vs Applicator Use) in Post-menopausal Women application of the vaginal estrogen cream - Postmenopausal Atrophic Vaginitis, Genitourinary Syndrome of Menopause | Phase 4 | Not yet recruiting | Walter Reed National Military Medical Center | 110 | 2025-02-01 | 2025-02-05 |
| Vaginal CO2 Laser Therapy for Genitourinary Syndrome in Breast Cancer Survivors SmartXIDE2V2LR, Monalisa Touch, DEKA, Florence, Italy - Genitourinary Syndrome of Menopause | Not applicable | Recruiting | University of Aarhus | 60 | 2024-12-01 | 2024-12-05 |
| The Efficacy of Topical Vaginal Oxytocin Gel in Postmenopausal Women With Vulvovaginal Atrophy Oxytocin, Hydroxypropyl methylcellulose - Vaginal Atrophy, Genitourinary Syndrome of Menopause | Phase 3 | Unknown | Oxagon | 244 | 2024-09-01 | 2024-07-23 |
| Combination of the Vaginal Laser With a Moisturizing and Repairing Niosomal Gel in the Treatment of Genitourinary Syndrome in Oncology Patients CO2 laser - Genitourinary Syndrome of Menopause | Unknown | Hospital Universitari de Bellvitge | 30 | 2024-07-01 | 2024-07-29 | |
| Efficacy of Non-Ablative Radiofrequency on Vaginal and Sexual Health in Postmenopausal Women Non-ablative monopolar radiofrequency treatment - Genitourinary Syndrome of Menopause, Vaginal Health | Not applicable | Completed | University of Castilla-La Mancha | 62 | 2024-06-15 | 2026-08-17 |
| Efficacy of the Use of Cellular Matrix/ A-CP-HA Kit Cellular Matrix / A-CP-HA Kit, Local estrogen therapy (Blissel, estriol 50 micrograms/g vaginal gel) - Genitourinary Syndrome of Menopause | Phase 4 | Completed | Fundación Santiago Dexeus Font | 192 | 2024-05-30 | 2026-09-21 |
| Vaginal Ecosystem and Network in the United States Study Vaginal Swab Collection - Bacterial Vaginosis, Candidiasis | Enrolling by invitation | Vaginal Biome Science | 3250 | 2024-05-16 | 2025-07-01 | |
| PRP Injections for Genitourinary Syndrome of Menopause Injection of platelet-rich plasma, Injection of saline - PRP, Sexual Function Disturbances | Not applicable | Active not recruiting | Medstar Health Research Institute | 30 | 2024-03-01 | 2025-11-14 |
| Changes in the Impact of Genitourinary Syndrome of Menopause With a Novel Nonhormonal Vulvovaginal Gel Assessed by PROMs. Hormone-free vulvovaginal gel with the tested composition XCMIM20m - Vulvar Atrophy, Vulvovaginal Signs and Symptoms | Not applicable | Recruiting | Mucosa Innovations, S.L. | 80 | 2024-01-08 | 2026-03-30 |
| Effects of Pelvic Floor Muscle Training With Patient Education in Genitourinary Syndrome of Menopause Pelvic floor exercise training, Patient education - Genitourinary Syndrome of Menopause | Not applicable | Completed | Hacettepe University | 50 | 2024-01-03 | 2026-06-04 |
| Vaginal Hyaluronic Acid, Arginine and Liposome Gel Versus Vaginal Lubricant in Postmenopausal Women With Genitourinary Syndrome of Menopause Vaginal Gel, Vaginal lubricant - Menopause Related Conditions, Atrophic Vaginitis | Phase 2 / Phase 3 | Unknown | Sarawak General Hospital | 52 | 2024-01-01 | 2023-12-28 |
| Changes in Neighbouring Microbiota in Genitourinary Syndrome Vaginal Cream with Applicator - Genitourinary Syndrome of Menopause | Phase 4 | Completed | Koc University Hospital | 31 | 2023-11-10 | 2024-10-09 |
| Comparison of Vaginal Hyaluronic Acid Treatment Over Autologous Platelet Rich Plasma Treatment for Genitourinary Syndrome of Menopause Platelet Rich Plasma treatment, Vaginal Hyaluronic Acid supplement - Genitourinary Syndrome of Menopause | Not applicable | Unknown | Kanuni Sultan Suleyman Training and Research Hospital | 60 | 2023-11-01 | 2024-03-05 |
| VALOR: Vaginal Atrophy & Long-term Observation of Recovery 7-0940 - Atrophic Vaginitis, Vaginal Atrophy | Not applicable | Recruiting | Stratpharma AG | 2000 | 2023-10-30 | 2026-02-20 |
| Concomitant Treatment with Topical Hyaluronic Acid and High Concentration Oxygen Therapy (Vaginal Natural Oxygenation Device - VNOD) in the Improvement of Symptoms Related to Genitourinary Syndrome of Menopause in Women with Natural and Oncological Postmenopause: Open-Label, Single-Center, Randomize High-concentration vaginal oxygen therapy (Caress Flow) with topical hyaluronic acid, hyaluronic acid-based gel (Hydeal-D®) - Genitourinary Syndrome of Menopause | Not applicable | Recruiting | Fondazione IRCCS Policlinico San Matteo di Pavia | 80 | 2023-10-16 | 2025-03-17 |
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Breast Neoplasms (7) · Sexual Dysfunction, Physiological (5) · Dyspareunia (4) · Atrophic Vaginitis (3) · Lichen Sclerosus et Atrophicus (2) · Sexual Dysfunctions, Psychological (2) · Urinary Incontinence (2) · Urinary Tract Infections (2) · Vulvar Lichen Sclerosus (2) · Atrophy (1) · Breast Carcinoma In Situ (1) · Candidiasis (1) · Coitus (1) · Endometriosis (1) · Lichen Planus (1)
Urogenital Diseases (15) · Genital Diseases (13) · Female Urogenital Diseases (11) · Female Urogenital Diseases and Pregnancy Complications (11) · Skin Diseases (10) · Skin and Connective Tissue Diseases (10) · Genital Diseases, Female (9) · Breast Diseases (8) · Neoplasms (8) · Neoplasms by Site (8) · Male Urogenital Diseases (7) · Mental Disorders (6) · Genital Diseases, Male (4) · Sexual Dysfunction, Physiological (4) · Sexual Dysfunctions, Psychological (4)
Lasers, Gas (3) · Vaginal Creams, Foams, and Jellies (3) · Dehydroepiandrosterone (2) · Control Groups (1) · Drugs, Generic (1) · Estradiol (1) · Estriol (1) · Hypromellose Derivatives (1) · Lasers (1) · Ospemifene (1) · Oxytocin (1) · Patient Education as Topic (1) · Surveys and Questionnaires (1) · Tomography, Optical Coherence (1) · Zinc (1)
Hospital Clinic of Barcelona (3) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (2) · King's College Hospital NHS Trust (2) · Maltepe University (2) · Stratpharma AG (2) · University of California, Irvine (2) · 1st Federal Budgetary Healthcare Institution Volga District Medical Center (1) · AVeta Medical (1) · Alexandria University (1) · Angelica Lindén Hirschberg (1) · Center for Vulvovaginal Disorders (1) · Centro de Atenção ao Assoalho Pélvico (1) · Chinese University of Hong Kong (1) · Dr. Amjad Khan (1) · Egymedicalpedia (1)
United States (12) · Spain (9) · Turkey (Türkiye) (6) · Italy (4) · Belgium (3) · Egypt (3) · Brazil (2) · United Kingdom (2) · Canada (1) · Denmark (1) · France (1) · Georgia (1) · Greece (1) · Hong Kong (1) · Israel (1)
Camil Castelo-Branco (2) · Felicia Lane, MD (2) · Kimberly Capone, PhD (2) · Abdulrahman Sinno, MD (1) · Ahinoam Lev-Sagie, MD (1) · Anita H. Chen, M.D. (1) · Arzu Msc Akdemir (1) · Assem Anwar (1) · Assem Anwar, Professor (1) · Fernand Labrie, MD (1) · Immaculada Alonso Vargas (1) · Jan Shifren, MD (1) · Juan M Ocampo-Godinez, M.D., Ph.D. (1)
PMID 18598765, PMID 21244215, PMID 25734980, PMID 26597311, PMID 26731686, PMID 28650869, PMID 34327510, PMID 34717608, PMID 36763359, PMID 37417970, PMID 38031020, PMID 38251861, PMID 39470875, PMID 40966714, PMID 41665827, PMID 41903372, PMID 42276807, PMID 42801790, PMID 42858690
2023 (1), R01EB030558 (1)