15 unknown, 9 completed, 6 recruiting, 2 not yet recruiting. 9 Not applicable, 6 Phase 4, 2 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Completed 4, Unknown 4, Recruiting 1 |
| Phase 4 | 6 | Recruiting 2, Unknown 2, Completed 1, Not yet recruiting 1 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
| Phase 1 | 1 | Unknown 1 |
Follow Gastric Intestinal Metaplasia: new trials by email Literature Review of Gastric Intestinal Metaplasia trials Research Report on Gastric Intestinal Metaplasia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AI-Based Risk Prediction Model for Upper Digestive Tract Cancer Gastric Cancer (GC), Premalignant Lesion | Not yet recruiting | National Taiwan University Hospital | 10000 | 2026-05-18 | 2026-05-28 | |
| REVerse Intestinal Metaplasia in the Stomach (REVISE) Pyrvinium, Placebo - Gastric Intestinal Metaplasia, Gastric Precancer | Phase 2 | Recruiting | Katherine Garman | 32 | 2025-12-15 | 2026-02-12 |
| Efficacy of an AI System in Training Endoscopists to Assess Gastric Intestinal Metaplasia Via the EGGIM Score AI-assisted EGGIM scoring, Conventional EGGIM scoring - Gastric Intestinal Metaplasia | Not applicable | Recruiting | Qilu Hospital of Shandong University | 8 | 2025-11-30 | 2026-09-08 |
| Efficacy and Safety of Berberine for Gastric Intestinal Metaplasia Berberine hydrochloride, Placebo - Gastric Intestinal Metaplasia | Phase 4 | Not yet recruiting | Xijing Hospital of Digestive Diseases | 204 | 2025-10-01 | 2025-09-04 |
| Efficacy and Safety of Weifuchun Tablet in Reversing Gastric Intestinal Metaplasia Weifuchun, Folic Acid - Gastric Intestinal Metaplasia | Phase 4 | Recruiting | Yongquan Shi | 400 | 2025-02-28 | 2026-08-06 |
| Efficacy and Safety of Ursodeoxycholic Acid in Reversing Gastric Intestinal Metaplasia Ursodeoxycholic Acid, Placebo - Gastric Intestinal Metaplasia | Phase 4 | Recruiting | Yongquan Shi | 196 | 2024-11-12 | 2025-12-05 |
| A Study Collecting Health Information to Understand and Prevent Gastric Cancer Questionnaire - Gastric Atrophy, Gastric Intestinal Metaplasia | Recruiting | Memorial Sloan Kettering Cancer Center | 3200 | 2024-04-11 | 2026-01-30 | |
| Cytosponge for Gastric Intestinal Metaplasia Cytosponge-TFF3 - Gastric Cancer, Gastric Intestinal Metaplasia | Unknown | University of Cambridge | 226 | 2023-10-16 | 2024-05-08 | |
| Automatic Evaluation of the Severity of Gastric Intestinal Metaplasia With Pathology Artificial Intelligence Diagnosis System The diagnosis of Artificial Intelligence and pathologists - Gastric Intestinal Metaplasia, Artificial Intelligence | Unknown | Shandong University | 150 | 2022-08-01 | 2023-09-06 | |
| Metformin Efficacy and Safety for Gastric Intestinal Metaplasia Metformin, Folate - Gastric Intestinal Metaplasia | Phase 4 | Completed | Xijing Hospital of Digestive Diseases | 140 | 2022-04-01 | 2024-09-23 |
| Endoscopic Grading of Intestinal Metaplasia Narrow-band imaging endoscopy - Narrow-band Imaging, Magnifying Endoscopy | Completed | Soonchunhyang University Hospital | 242 | 2022-03-01 | 2023-04-25 | |
| Diagnostic Performance Indicators in Upper GI Endoscopy:PROSPERO Study Esophageal Cancer, Gastric Cancer | Unknown | University of Cambridge | 1000 | 2021-06-01 | 2021-04-15 | |
| Validation of an Artificial Intelligence System Based on Raman Spectroscopy for Diagnosis of Gastric Premalignant Lesions and Early Gastric Cancer Raman spectroscopy based device (SPECTRA IMDx) - Gastric Dysplasia, Gastric Intestinal Metaplasia | Not applicable | Unknown | Changi General Hospital | 100 | 2021-05-01 | 2021-05-03 |
| RFA for GIM Treatment Radiofrequency ablation (RFA) - Gastric Intestinal Metaplasia, Treatment | Not applicable | Completed | King Chulalongkorn Memorial Hospital | 50 | 2020-06-01 | 2023-08-01 |
| Microbiome Analysis in Gastric Intestinal Metaplasia and in Gastric Cancer and Subtypes Correlation Gastroscopy - Gastric Intestinal Metaplasia, Gastric Cancer | Unknown | University Hospital, Ioannina | 80 | 2020-04-18 | 2020-04-28 | |
| Confocal Laser Endomicroscopy With Cresyl Violet for in Vivo Diagnosis of Gastric Intestinal Metaplasia Cresyl violet - Gastric Intestinal Metaplasia | Not applicable | Completed | Shandong University | 48 | 2018-09-16 | 2019-05-14 |
| Surveillance of Patients With Precancerous Lesions of the Stomach Upper endoscopy with biopsies, Plasma/serum sampling, Biopsies for gastric microbiota - Gastric Cancer, Gastric Intestinal Metaplasia | Recruiting | University of Latvia | 2000 | 2017-06-19 | 2018-08-21 | |
| A Comparison of pCLE Based Targeted Biopsy and WLE Based Standard Biopsy in Staging the Operative Link on Gastric Intestinal Metaplasia (OLGIM): A Randomized，Cross-over Study Patients in Group 1 will receive pCLE at first and WLE 2 months later, patients in Group 2 will receive WLE at first and pCLE 2 months later. - Gastric Intestinal Metaplasia, Confocal Laser Endomicroscopy | Phase 4 | Unknown | Shandong University | 40 | 2016-10-01 | 2016-10-12 |
| Chemoprevention of Gastric Carcinogenesis Eflornithine, Eflornithine placebo - Gastric Cancer, Gastric Intestinal Metaplasia | Phase 2 | Completed | Vanderbilt-Ingram Cancer Center | 91 | 2016-09-19 | 2026-09-02 |
| The Efficacy of Severe Whitening and Delayed Fading in Acetic Acid-enhanced Endoscopy for Diagnosing Gastric Intestinal Metaplasia acetic acid-enhanced endoscopy, Acetic Acid, endoscope - Gastric Intestinal Metaplasia | Phase 1 | Unknown | Shandong University | 100 | 2016-06-01 | 2016-06-20 |
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Stomach Neoplasms (12) · Gastritis, Atrophic (6) · Esophageal Neoplasms (2) · Barrett Esophagus (1) · Duodenal Neoplasms (1) · Polyposis, Gastric (1)
Digestive System Diseases (12) · Digestive System Neoplasms (12) · Gastrointestinal Diseases (12) · Gastrointestinal Neoplasms (12) · Neoplasms (12) · Neoplasms by Site (12) · Stomach Diseases (12) · Gastritis (6) · Gastroenteritis (6) · Esophageal Diseases (2) · Head and Neck Neoplasms (2) · Duodenal Diseases (1) · Intestinal Diseases (1) · Intestinal Neoplasms (1) · Precancerous Conditions (1)
Folic Acid (2) · Gastroscopy (2) · Acetic Acid (1) · Biopsy (1) · Blood Specimen Collection (1) · Eflornithine (1) · Endoscopes (1) · Endoscopy, Digestive System (1) · Metformin (1) · Narrow Band Imaging (1) · Radiofrequency Ablation (1) · Surveys and Questionnaires (1) · Ursodeoxycholic Acid (1) · pyrvinium (1) · weifuchun (1)
Shandong University (11) · King Chulalongkorn Memorial Hospital (4) · Changi General Hospital (2) · University of Cambridge (2) · Xijing Hospital of Digestive Diseases (2) · Yongquan Shi (2) · Katherine Garman (1) · Memorial Sloan Kettering Cancer Center (1) · National Taiwan University Hospital (1) · National University Hospital, Singapore (1) · Qilu Hospital of Shandong University (1) · Soonchunhyang University Hospital (1) · University Hospital, Ioannina (1) · University of Latvia (1) · Vanderbilt-Ingram Cancer Center (1)
China (15) · Singapore (4) · Thailand (4) · United States (2) · Australia (1) · Greece (1) · Honduras (1) · Latvia (1) · Puerto Rico (1) · South Korea (1) · United Kingdom (1)
Rapat Pittayanon, MD (2) · Rungsun Rerknimitr, Professor (2) · Yanqing Li, MD, PhD (2) · Yanqing Li, PhD. MD. (2) · Yongquan Shi, PhD (2) · Andreas Hadjicinolaou, MD PhD (1) · Andreas V Hadjinicolaou (1) · Chin Kimg Tan, MD (1) · Doug Morgan, MD (1) · George Pappas-Gogos, Dr (1) · Ines Modolell, MD (1) · Jun-Hyung Cho, M.D. (1) · Katherine Garman, MD (1) · Keith Wilson, MD (1)
PMID 23432088, PMID 40518567, PMID 41801147
R01CA190612 (1)