4 terminated. 4 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Terminated 4 |
| Phase 1 | 2 | Terminated 2 |
Follow Frontotemporal Lobar Degeneration: new trials by email Literature Review of Frontotemporal Lobar Degeneration trials Research Report on Frontotemporal Lobar Degeneration
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nabilone for Agitation in Frontotemporal Dementia Nabilone, Placebo - Frontotemporal Dementia, Frontotemporal Dementia, Behavioral Variant | Phase 2 | Terminated | Simon Ducharme, MD | 3 | 2023-03-07 | 2026-07-28 |
| Open-label Extension (OLE) Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) and/or Frontotemporal Dementia (FTD) WVE-004 10 mg Q12W - Amyotrophic Lateral Sclerosis, Frontotemporal Dementia | Phase 1 / Phase 2 | Terminated | Wave Life Sciences USA, Inc. | 8 | 2022-12-14 | 2026-09-09 |
| A Study of PBFT02 in Participants With FTD and Mutations in the Granulin Precursor (GRN) or C9ORF72 Genes PBFT02 - Frontotemporal Dementia, FTD | Phase 1 / Phase 2 | Terminated | Passage Bio, Inc. | 30 | 2021-09-14 | 2026-10-29 |
| Intranasal Insulin in Frontotemporal Dementia (FTD) Novolin-R insulin - Frontotemporal Dementia, Behavioral Variant | Phase 2 | Terminated | HealthPartners Institute | 3 | 2019-09-09 | 2023-10-27 |
Frontotemporal Dementia (3) · Pick Disease of the Brain (3) · Amyotrophic Lateral Sclerosis (1) · Aphasia, Primary Progressive (1) · Dementia (1) · Frontotemporal Dementia With Motor Neuron Disease (1) · Insulin Resistance (1) · Psychomotor Agitation (1)
Brain Diseases (4) · Central Nervous System Diseases (4) · Mental Disorders (4) · Metabolic Diseases (4) · Nervous System Diseases (4) · Neurocognitive Disorders (4) · Nutritional and Metabolic Diseases (4) · Dementia (3) · Neurodegenerative Diseases (3) · Proteostasis Deficiencies (3) · TDP-43 Proteinopathies (3) · Aberrant Motor Behavior in Dementia (1) · Aphasia (1) · Behavior (1)
HealthPartners Institute (1) · Passage Bio, Inc. (1) · Simon Ducharme, MD (1) · Wave Life Sciences USA, Inc. (1)
Canada (2) · United States (2) · Australia (1) · Brazil (1) · Netherlands (1) · Portugal (1) · United Kingdom (1)