4 enrolling by invitation. 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Enrolling by invitation 4 |
Follow Frontotemporal Lobar Degeneration: new trials by email Literature Review of Frontotemporal Lobar Degeneration trials Research Report on Frontotemporal Lobar Degeneration
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Alzheimer's Tau Platform: Regimen A - AADvac1 AADvac1, Donanemab - Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease | Phase 2 | Enrolling by invitation | Paul S. Aisen | 450 | 2026-11-03 | 2026-10-26 |
| The Progressive Supranuclear Palsy Clinical Trial Platform - Regimen B: LM11A-31 LM11A-31, Matching Placebo - PSP - Progressive Supranuclear Palsy | Phase 2 | Enrolling by invitation | Adam Boxer | 147 | 2026-07-29 | 2026-08-12 |
| The Progressive Supranuclear Palsy Clinical Trial Platform - Regimen A: AADvac1 AADvac1, Matching Placebo - PSP - Progressive Supranuclear Palsy | Phase 2 | Enrolling by invitation | Adam Boxer | 146 | 2026-07-29 | 2026-08-13 |
| Tau PET Imaging in the Northern Manhattan Study of Metabolism and Mind. 18F-MK6240 injection - Diabetes Mellitus, Type 2, Pre-diabetes | Phase 2 | Enrolling by invitation | Columbia University | 600 | 2018-07-24 | 2025-05-06 |
Frontotemporal Dementia (2) · Pick Disease of the Brain (2) · Supranuclear Palsy, Progressive (2) · Alzheimer Disease (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Glucose Intolerance (1) · Hyperglycemia (1)
Brain Diseases (4) · Central Nervous System Diseases (4) · Dementia (4) · Mental Disorders (4) · Nervous System Diseases (4) · Neurocognitive Disorders (4) · Metabolic Diseases (3) · Neurodegenerative Diseases (3) · Nutritional and Metabolic Diseases (3) · Tauopathies (3) · Basal Ganglia Diseases (2) · Cranial Nerve Diseases (2) · Eye Diseases (2) · Frontotemporal Dementia (2)
AADvac1 (2) · LM11A-31 (1) · MK-6240 (1) · donanemab (1)
Adam Boxer (2) · Columbia University (1) · Paul S. Aisen (1)
United States (4)
Adam Boxer, MD, PhD (3) · Anne-Marie Wills, MD (2) · Irene Litvan, MD (2) · Julio Rojas-Martinez, MD, PhD (2) · Jose A. Luchsinger, MD (1) · Keith Johnson, MD (1)
R01AG085029 (2), R01AG050440 (1), R01AG055299 (1), R01AG078457 (1), RF1AG051556 (1)