6 completed, 1 not yet recruiting, 1 recruiting, 1 unknown. 6 Not applicable, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 4, Not yet recruiting 1, Unknown 1 |
| Phase 4 | 2 | Completed 1, Recruiting 1 |
Follow Free Flap: new trials by email Literature Review of Free Flap trials Research Report on Free Flap
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparing Intraoperative Indocyanine Green Fluorescence Imaging With Standard Clinical Assessment for Flap Perfusion in Head and Neck Reconstruction (VISION Trial) Indocyanine Green, Standard clinical perfusion assessment - Head and Neck Cancer (H&N), Free Tissue Flaps | Phase 4 | Recruiting | Region Skane | 244 | 2026-09-28 | 2026-09-29 |
| Resection and Defect Repair of Oral Cancer Aided by Mixed Reality Technology Unreal Engine 5 (UE5)-based Mixed Reality (MR) Technology-assisted Resection of Oral Cancer and Defect Reconstruction, Virtual Surgical Guide Technology-assisted Resection of Oral Cancer and Defect Reconstruction - Tongue Squamous Cell Carcinoma, Mixed Reality | Not applicable | Not yet recruiting | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | 30 | 2026-04-01 | 2026-03-20 |
| Investigating the Impact of Indocyanine Green Titration on Fluorescent Intensity in Free Flap : An Exploration of Alternative Indicators Indocyanine Green Fluorescence (ICG), Temperature, Transcutaneous oxygen and carbon dioxide pressure - Free Flap, Indocyanine Green | Not applicable | Unknown | Universitas Indonesia | 63 | 2023-01-01 | 2024-03-15 |
| Non-invasive Remote Ischemic PreConditioning (RIPC) in Free Flaps for Breast Reconstruction Remote ischemic preconditiong - Ischemia-Reperfusion Injury, Free Flap | Not applicable | Completed | Ruhr University of Bochum | 49 | 2021-04-01 | 2026-03-25 |
| Platelet-Rich Fibrin in the Healing of Regional and Free Flaps Platelet Rich Fibrin (PRF) Application - Head and Neck Disorder, Free Flap | Not applicable | Completed | University of Florida | 3 | 2019-12-16 | 2020-09-30 |
| Impact of Negative Pressure Wound Therapy on Free Muscle Flaps V.A.C. UltraTM (KCI®,San Antonio, Texas, USA) - Negative-Pressure Wound Therapy, Edema | Not applicable | Completed | Ulf Dornseifer, MD | 26 | 2015-08-01 | 2023-01-25 |
| Head and Neck Quality of Life Head and Neck Cancer, Free Flap | Completed | Chang Gung Memorial Hospital | 315 | 2015-03-01 | 2025-01-03 | |
| Impact of Active Thermoregulation on the Microcirculation of Free Flaps Hilotherm Clinic® - Microcirculation, Thermoregulation | Not applicable | Completed | Ulf Dornseifer, MD | 25 | 2013-11-01 | 2015-07-07 |
| Assessment of the Effects of Pressors on Graft Blood Flow After Free Tissue Transfer Surgery Epinephrine, Norepinephrine, Dobutamine - Oral Cancer, Head and Neck Cancer | Phase 4 | Completed | Oxford University Hospitals NHS Trust | 25 | 2008-10-01 | 2011-08-16 |
Head and Neck Neoplasms (3) · Mouth Neoplasms (2) · Body Temperature Changes (1) · Edema (1) · Hypotension (1) · Ischemia (1) · Reperfusion Injury (1)
Neoplasms (4) · Neoplasms by Site (4) · Pathological Conditions, Signs and Symptoms (3) · Cardiovascular Diseases (2) · Mouth Diseases (2) · Signs and Symptoms (2) · Stomatognathic Diseases (2) · Vascular Diseases (2) · Head and Neck Neoplasms (1) · Pathologic Processes (1) · Postoperative Complications (1)
Blood Gas Monitoring, Transcutaneous (1) · Dobutamine (1) · Epinephrine (1) · Indocyanine Green (1) · Norepinephrine (1) · Prolactin-Releasing Hormone (1) · Temperature (1) · dopexamine (1)
Ulf Dornseifer, MD (2) · Chang Gung Memorial Hospital (1) · Oxford University Hospitals NHS Trust (1) · Region Skane (1) · Ruhr University of Bochum (1) · Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University (1) · Universitas Indonesia (1) · University of Florida (1)
Germany (3) · China (1) · Indonesia (1) · Sweden (1) · Taiwan (1) · United Kingdom (1) · United States (1)
Parintosa Atmodiwirjo (1) · Pooya Rajabaleyan, MD, PhD (1) · Salam Salman, MD, DDS (1) · Stephen R Watt-Smith, FDSRCS, MD (1) · Ulf Dornseifer, M.D. (1) · Ulf Dornseifer, MD (1)
PMID 22929242, PMID 40771071, PMID 41381697
2008 (1), 2025 (1)