Facial Nerve Diseases: Clinical Trials

126 completed, 57 unknown, 36 recruiting, 27 not yet recruiting. 151 Not applicable, 25 Phase 2, 17 Phase 1, 17 Phase 4, 13 Phase 3.

By phase and status

Phase	Trials	Status
Not applicable	151	Completed 65, Unknown 31, Not yet recruiting 18, Recruiting 16, Active not recruiting 8, Terminated 8, Enrolling by invitation 3, Suspended 1, Withdrawn 1
Phase 2	25	Completed 10, Recruiting 4, Terminated 4, Unknown 4, Withdrawn 2, Active not recruiting 1
Phase 1	17	Completed 5, Recruiting 5, Unknown 4, Terminated 2, Withdrawn 1
Phase 4	17	Completed 10, Unknown 3, Withdrawn 2, Active not recruiting 1, Recruiting 1
Phase 3	13	Withdrawn 4, Completed 3, Unknown 3, Active not recruiting 1, Not yet recruiting 1, Terminated 1
Early Phase 1	7	Unknown 3, Recruiting 2, Completed 1, Withdrawn 1

Follow Facial Nerve Diseases: new trials by email Literature Review of Facial Nerve Diseases trials Research Report on Facial Nerve Diseases

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Focused Versus Multi-Target Trigger Point Injection for Chronic Myofascial Neck Pain Lidocaine 1% Trigger Point Injection - Myofacial Pain Syndrome, Chronic Neck Pain	Not applicable	Not yet recruiting	Mardin Artuklu University	100	2027-04-01	2026-10-20
Evaluation of the Effect of Adding Sodium Bicarbonate to Lidocaine in the Treatment of Myofascial Pain Syndrome Lidocaine 2 %, Lidocaine + Sodium Bicarbonate - Myofacial Pain, Myofacial Pain Syndrome	Not applicable	Recruiting	Cairo University	30	2026-11-01	2026-10-21
RP-008 in Combination With Daily Oral Varenicline for the Treatment of Trigeminal Neuralgia RP-008, Varenicline tartrate - Trigeminal Neuralgia	Phase 1 / Phase 2	Recruiting	Kriya Therapeutics, Inc.	24	2026-09-10	2026-10-23
Safety-zone Approach and Facial Nerve Preservation in Transbuccal-accessed Fixation of Mandibular Fractures Landmarking Safety-zone - Facial Nerve Injuries, Mandibular Fractures	Not applicable	Recruiting	Delta University for Science and Technology	16	2026-09-05	2026-09-09
Study on the Optimal Waveform Patterns of Electroacupuncture Targeted Intervention for Bell's Palsy Based on Surface Electromyography Characteristics electroacupuncture waveform - Bell's Palsy	Not applicable	Not yet recruiting	The Third Affiliated hospital of Zhejiang Chinese Medical University	100	2026-09-01	2026-09-02
Electroacupuncture With Two Pulse Patterns for Bell's Palsy Using Surface Electromyography Evaluation sham EA, Electroacupunture(continuous pulse pattern), Electroacupuncture(intermittent pulse pattern) - Bell Palsy	Not applicable	Not yet recruiting	The First Affiliated Hospital of Zhejiang Chinese Medical University	111	2026-09-01	2026-09-02
Clinical Efficacy and Peripheral Ultrasound Mechanism of Trigger Point Bloodletting Therapy for Primary Trigeminal Neuralgia Trigger Point Bloodletting Therapy, Carbamazepine - Trigeminal Neuralgia (TN)	Not applicable	Not yet recruiting	Beijing Hospital of Traditional Chinese Medicine	60	2026-08-31	2026-08-06
Efficacy and Safety of Oral Antiviral Therapy for Idiopathic Trigeminal Neuralgia Intervention：Drug: Carbamazepine, Intervention：Drug: Carbamazepine + Acyclovir, Intervention：Drug: Carbamazepine + Celecoxib - Idiopathic Trigeminal Neuralgia	Not applicable	Not yet recruiting	Beijing Tiantan Hospital	165	2026-08-31	2026-06-29
Management of Arachnoid Nerve Tethering in Trigeminal Neuralagia Arachnoid nerve detethering - Trigeminal Neuralgia	Not applicable	Not yet recruiting	Assiut University	23	2026-08-31	2026-09-10
Turkish Validation of the Synkinesis Assessment Questionnaire (SAQ) Synkinesis Assessment Questionnaire (SAQ) - Facial Paralysis, Facial Palsy		Enrolling by invitation	Barış CELBEK	49	2026-08-15	2026-08-10
Treatment for "Asymmetric Crying Facies" Botulinium toxin type A injection - Hemifacial Microsomia, Facial Nerve Paralysis	Not applicable	Recruiting	Xiaolei Jin	60	2026-08-07	2026-09-28
A Real-Time Magnetic Device Prototype for Temporary Management of Paralytic Lagophthalmos Magnetic device prototype - Paralytic Lagophthalmos	Not applicable	Suspended	E-DA Hospital	12	2026-08-01	2025-08-14
Dry Needling and Low-Level Laser Microcurrent Electrical Stimulation for Myofascial Pain Syndrome Dry Needle, Low-Level Laser Microcurrent Electrical Stimulation, Sham Dry Needle - Myofacial Pain Syndrome	Not applicable	Recruiting	Udayana University	80	2026-07-30	2026-08-10
Effect of Low Energy Extracorporeal Shockwave on Patients With Bell's Palsy Low energy extracorporeal shockwave therapy, Selective physical therapy program - Bell Palsy	Not applicable	Not yet recruiting	Cairo University	42	2026-06-25	2026-06-22
Validation of Artificial Intelligence-Based Facial Paralysis Assessment in Patients With Bell's Palsy Sunnybrook Facial Grading System (FGS), AI-Based Facial Assessment - Bell's Palsy, Facial Nerve Paralysis		Not yet recruiting	Cairo University	63	2026-06-01	2026-05-07
High-intensity Laser Therapy Versus Low Level Laser Therapy in the Treatment of Trigeminal Neuralgia 1064 nm Nd-YAG Laser, 940 nm Diode laser - Trigeminal Neuralgia	Not applicable	Not yet recruiting	Alexandria University	38	2026-05-15	2026-05-15
Relationship Between Facial Palsy and Psychological Distress Facial Palsy		Not yet recruiting	Cairo University	85	2026-04-15	2026-04-09
Identification of Possible Trigeminal Neuralgia Completion of the IDTN Questionnaire - Trigeminal Neuralgia (TN), Orofacial Pain		Not yet recruiting	University College, London	250	2026-04-01	2026-03-23
Resting-State fMRI Study of Functional Connectivity After Gamma Knife Radiosurgery in Trigeminal Neuralgia Resting-State Functional MRI - Trigeminal Neuralgia	Not applicable	Not yet recruiting	Assistance Publique Hopitaux De Marseille	28	2026-04-01	2026-01-21
Surgeons' Prediction of Dental Surgery Complications and the Influence of Patient Characteristics: Development of an AI Model Postoperative Infections, Mandibular Nerve Injuries		Not yet recruiting	University of Copenhagen	3000	2026-04-01	2026-03-10

Showing 20 of 286. Sign in to see all of them.

Narrower conditions

Trigeminal Neuralgia (136)  ·  Bell Palsy (83)  ·  Facial Neuralgia (28)  ·  Facial Paralysis (28)  ·  Facial Pain (19)  ·  Neuralgia (14)  ·  Mandibular Nerve Injuries (10)  ·  Pain (10)  ·  Facial Nerve Injuries (9)  ·  Cluster Headache (8)  ·  Facial Asymmetry (6)  ·  Myofascial Pain Syndromes (6)  ·  Trigeminal Nerve Diseases (6)  ·  Facial Hemiatrophy (5)

Broader conditions

Mouth Diseases (286)  ·  Nervous System Diseases (286)  ·  Stomatognathic Diseases (285)  ·  Cranial Nerve Diseases (284)  ·  Facial Neuralgia (154)  ·  Trigeminal Nerve Diseases (150)  ·  Pathological Conditions, Signs and Symptoms (90)  ·  Infections (86)  ·  DNA Virus Infections (85)  ·  Herpesviridae Infections (85)  ·  Virus Diseases (85)  ·  Signs and Symptoms (84)  ·  Neurologic Manifestations (83)  ·  Pain (34)

Interventions

Botulinum Toxins, Type A (10)  ·  Lidocaine (8)  ·  Low-Level Light Therapy (8)  ·  Carbamazepine (7)  ·  Muscle Stretching Exercises (5)  ·  Oxcarbazepine (5)  ·  Prednisolone (5)  ·  Sodium Chloride (5)  ·  vixotrigine (5)  ·  Acupuncture Therapy (4)  ·  Electroacupuncture (4)  ·  Pulsed Radiofrequency Treatment (4)  ·  Radiosurgery (4)  ·  Electric Stimulation (3)  ·  Exercise (3)

Sponsors

Beijing Tiantan Hospital (9)  ·  Riphah International University (9)  ·  Assiut University (7)  ·  Cairo University (7)  ·  Biogen (6)  ·  Danish Headache Center (6)  ·  Stanford University (6)  ·  Beijing Tongren Hospital (4)  ·  University Health Network, Toronto (4)  ·  University of Lahore (4)  ·  University of Minnesota (4)  ·  Alexandria University (3)  ·  Chang Gung Memorial Hospital (3)  ·  Diskapi Teaching and Research Hospital (3)  ·  Neurotrigger Ltd (3)

Countries

United States (54)  ·  China (34)  ·  Turkey (Türkiye) (25)  ·  Egypt (23)  ·  Pakistan (23)  ·  Canada (11)  ·  United Kingdom (11)  ·  Italy (7)  ·  Denmark (6)  ·  France (6)  ·  Taiwan (6)  ·  Israel (4)  ·  Belgium (3)  ·  Germany (3)  ·  India (3)

Top investigators

Clara Choi (3)  ·  Fang Luo, M.D. (3)  ·  Scott Soltys (3)  ·  Ahmed A Bessar, MD, PhD (2)  ·  Dr Aruba Saeed, PHD* (2)  ·  Erling A Tronvik, PhD, MD (2)  ·  Mojgan Hodaie, MD, MSc (2)  ·  Wei Wang, doctor (2)  ·  Abdelmoez Mohamed El-Sharkawy, Associate professor (1)  ·  Abdelrady S Ibrahim, M.D. (1)  ·  Abdul Karim Khalil, PHD (1)  ·  Adam Sivitz, MD (1)  ·  Adham Yehia Zakaria, Lecturer (1)  ·  Ahmed A Hashem, PhD (1)

Results publications

PMID 1527657, PMID 10503856, PMID 10630935, PMID 10916328, PMID 12140424, PMID 12544040, PMID 12621288, PMID 14762747, PMID 15225944, PMID 15346360, PMID 15464564, PMID 15620776, PMID 15793381, PMID 16192853, PMID 16436823, PMID 16480503, PMID 16565685, PMID 17096156, PMID 17113444, PMID 17258129, PMID 17448850, PMID 18077952, PMID 18088730, PMID 18164488, PMID 18368417, PMID 18849193, PMID 18981841, PMID 19039051, PMID 19146143, PMID 19231779, PMID 20006669, PMID 20083736, PMID 20093325, PMID 20227216, PMID 20419329, PMID 20461515, PMID 20492571, PMID 20521077, PMID 20663600, PMID 21116663, PMID 21119445, PMID 21422774, PMID 21435214, PMID 21621166, PMID 21693007, PMID 21778851, PMID 2212022, PMID 22151211, PMID 22440318, PMID 22652942

NIH funding

2016 (3), 2017 (2), 2014 (1), 2015 (1), K23NS050485 (1)