4 completed, 3 unknown, 1 active not recruiting, 1 recruiting. 11 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 11 | Completed 4, Unknown 3, Active not recruiting 1, Recruiting 1, Terminated 1, Withdrawn 1 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
Follow Facial Injuries: new trials by email Literature Review of Facial Injuries trials Research Report on Facial Injuries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pilot Study of ELK-003 Eye Drops for Treating Ocular Manifestations of Epidermolysis Bullosa ELK-003 (Standarized Amniotic Fluid Secretome Eye Drops) - Junctional Epidermolysis Bullosa, Epidermolysis Bullosa (EB) | Phase 1 | Active not recruiting | Fundación DEBRA Chile, Niños Piel de Cristal | 20 | 2024-05-07 | 2025-12-31 |
| Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Corneal Scars CSB-001 Ophthalmic Solution 0.1% - Corneal Scar | Phase 1 | Recruiting | Claris Biotherapeutics, Inc. | 20 | 2024-02-05 | 2026-04-07 |
| Evaluation of EpiBone-CMF for Mandibular Ramus Reconstruction EB-CMF - Mandible Tumor, Mandibular Injuries | Phase 1 / Phase 2 | Unknown | Epibone, Inc. | 6 | 2021-03-31 | 2022-05-27 |
| The Evaluation of Postoperative Antibiotics in Non-Infected Mandible Fractures Antibiotic treatment (Unasyn or Cleocin), Antibiotic treatment (Augmentin or Cleocin), Control Group - Jaw Fractures, Infection | Phase 1 | Terminated | The University of Texas Health Science Center, Houston | 13 | 2020-10-01 | 2025-06-26 |
| Study of the Safety of USB005 in Healthy Volunteers USB005 (aclerastide) Ophthalmic Solution, USB005 Ophthalmic Solution Placebo - Healthy Volunteers | Phase 1 | Completed | US Biotest, Inc. | 32 | 2018-07-25 | 2019-04-04 |
| Limbus-derived Stem Cells for Prevention of Postoperative Corneal Haze Stem cells, Vehicle - Corneal Scars and Opacities | Phase 1 | Unknown | L.V. Prasad Eye Institute | 15 | 2017-08-01 | 2019-02-26 |
| Stem Cells Therapy for Corneal Blindness Ex-vivo cultivated limbal stem cell pool - Corneal Injuries, Corneal Burns | Phase 1 | Unknown | L.V. Prasad Eye Institute | 100 | 2016-08-31 | 2018-03-06 |
| Limbal Stem Cell Deficiency (LSCD) Treatment With Cultivated Stem Cell (CALEC) Graft Biopsy to collect limbal epithelial stem cells that will be cultivated into a graft, Cultivation of Limbal epithelial cells into a graft, CALEC Transplant - Limbal Stem Cell Deficiency | Phase 1 / Phase 2 | Completed | Massachusetts Eye and Ear Infirmary | 23 | 2016-08-01 | 2025-01-15 |
| Utilization of Amniotic Membrane Extract Eye Drop (AMEED) on Human Corneal Healing Amniotic Membrane Extract Eye Drop - Cornea Injury | Phase 1 / Phase 2 | Completed | Royan Institute | 20 | 2014-06-01 | 2016-04-21 |
| Proparacaine vs Placebo for Corneal Injuries Proparacaine drops 0.05%, saline drops - Corneal Abrasions | Phase 1 | Completed | London Health Sciences Centre | 43 | 2005-10-01 | 2008-02-22 |
| The Application of Fibrin Glue in Ocular Surface Diseases tissue fibrin glue application (Tisseel) - Pterygium, Corneal Ulcer | Phase 1 | Withdrawn | National Taiwan University Hospital | 30 | 2005-04-01 | 2008-05-29 |
Corneal Injuries (8) · Agnosia (1) · Congenital Abnormalities (1) · Corneal Diseases (1) · Corneal Neovascularization (1) · Corneal Opacity (1) · Corneal Perforation (1) · Corneal Ulcer (1) · Epidermolysis Bullosa (1) · Epidermolysis Bullosa Dystrophica (1) · Epidermolysis Bullosa, Junctional (1) · Eye Injuries (1) · Infections (1) · Jaw Fractures (1) · Limbal Stem Cell Deficiency (1)
Craniocerebral Trauma (11) · Nervous System Diseases (11) · Trauma, Nervous System (11) · Wounds and Injuries (11) · Eye Diseases (9) · Corneal Diseases (8) · Eye Injuries (8) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Maxillofacial Injuries (2) · Pathological Conditions, Signs and Symptoms (2) · Bone Diseases (1) · Bone Neoplasms (1) · Collagen Diseases (1) · Congenital Abnormalities (1)
Amoxicillin-Potassium Clavulanate Combination (1) · Clindamycin (1) · Control Groups (1) · Fibrin Tissue Adhesive (1) · Ophthalmic Solutions (1) · aclerastide (1) · sultamicillin (1)
L.V. Prasad Eye Institute (2) · Claris Biotherapeutics, Inc. (1) · Epibone, Inc. (1) · Fundación DEBRA Chile, Niños Piel de Cristal (1) · London Health Sciences Centre (1) · Massachusetts Eye and Ear Infirmary (1) · National Taiwan University Hospital (1) · Royan Institute (1) · The University of Texas Health Science Center, Houston (1) · US Biotest, Inc. (1)
United States (5) · India (2) · Canada (1) · Chile (1) · Taiwan (1)
Vivek Singh, MSc PhD (2) · Brian R Gastman, MD (1) · Fatemeh Doostmohammadi, MD (1) · Fung-Rong Hu, MD (1) · Hamid Gourabi, PhD (1) · Jagadesh C Reddy, MBBS MD (1) · Khosro Jadidi, MD (1) · Marzieh Ebrahimi, PhD (1) · Michael Sheety, MD (1) · Nagi Demian, DDS/MD (1) · Pratik Gogri, MBBS MS (1) · Sayan Basu, MBBS MS (1) · Sayan Basu, MBBS, MS (1) · Scott B Anderson, MD FRCPC (1) · Ula Jurkunas, MD (1)