2 completed, 1 recruiting, 1 unknown. 4 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 2, Recruiting 1, Unknown 1 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
Follow Encephalomalacia: new trials by email Literature Review of Encephalomalacia trials Research Report on Encephalomalacia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neonatal White Matter Injury Trial (WRAP) Clemastine fumarate - White Matter Injury, Brain Injury, Fetus and Neonate | Phase 1 | Recruiting | Bridget LaMonica Ostrem, M.D., Ph.D. | 24 | 2026-07-26 | 2026-07-28 |
| A Study to Investigate the Safety and Efficacy of UC-MSCs in Pediatric Patients With Cerebral Palsy UDI-001 - Cerebral Palsy, Periventricular Leukomalacia | Phase 1 / Phase 2 | Completed | Rohto Pharmaceutical Co., Ltd. | 6 | 2021-06-02 | 2025-04-06 |
| Effects of Delayed Cord Clamp and/or Indomethacin on Preterm Infant Brain Injury Indomethacin, delay in umbilical cord clamp at birth, placebo infusion - Intraventricular Hemorrhage, Periventricular Leukomalacia | Phase 1 / Phase 2 | Completed | Hong Huang | 256 | 2014-08-01 | 2021-11-23 |
| Recombinant Erythropoietin for Neuroprotection in Very Preterm Infants recombinant human erythropoietin (rhEpo), Normal saline - Infant, Premature, Leukomalacia, Periventricular | Phase 1 / Phase 2 | Unknown | China Medical University Hospital | 100 | 2009-08-01 | 2009-05-29 |
Leukomalacia, Periventricular (4) · Brain Injuries (2) · Premature Birth (2) · Cerebral Palsy (1) · Retinopathy of Prematurity (1)
Brain Diseases (4) · Cardiovascular Diseases (4) · Central Nervous System Diseases (4) · Cerebrovascular Disorders (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Infant, Newborn, Diseases (4) · Infant, Premature, Diseases (4) · Nervous System Diseases (4) · Vascular Diseases (4) · Craniocerebral Trauma (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Obstetric Labor Complications (2) · Obstetric Labor, Premature (2) · Pregnancy Complications (2)
Clemastine (1) · Indomethacin (1) · Saline Solution (1)
Bridget LaMonica Ostrem, M.D., Ph.D. (1) · China Medical University Hospital (1) · Hong Huang (1) · Rohto Pharmaceutical Co., Ltd. (1)
United States (2) · Japan (1) · Taiwan (1)
Bai-Horng Su, MD, PhD (1) · Bridget Ostrem, MD, PhD (1) · Hong Huang, MD-PhD (1) · John Bauer, PhD (1) · Sumito Okawa (1) · Vicki Whitehead, RN (1)
1DP2NS148743-01 (1), R01HD070792 (1)