25 completed, 4 unknown, 3 terminated, 2 recruiting. 21 Not applicable, 7 Phase 2, 3 Phase 3, 3 Phase 4, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 21 | Completed 18, Unknown 2, Recruiting 1 |
| Phase 2 | 7 | Completed 4, Terminated 3 |
| Phase 3 | 3 | Completed 2, Recruiting 1 |
| Phase 4 | 3 | Unknown 2, Completed 1 |
| Early Phase 1 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Emotion-focused Therapy (EFT) on Mood Awareness and Emotional Reactivity in Bipolar Patients Awareness and Emotional Reactivity Emotion Focused Therapy application, scale form - Therapy, Directly Observed | Not applicable | Completed | Muğla Sıtkı Koçman University | 50 | 2025-05-21 | 2026-04-22 |
| Functional Electrostimulation on the Upper Lip in Multiple Sclerosis Fesia Grasp, GLOBUS ELITE - Electrode Site Reaction, Therapy | Not applicable | Unknown | Universidad de Burgos | 30 | 2025-01-20 | 2024-10-15 |
| Project ASTHMA - Aligning With Schools To Help Manage Asthma and Improve Outcomes APP assessment and management of asthma - Asthma in Children, Directly Observed Therapy | Not applicable | Recruiting | State University of New York at Buffalo | 400 | 2024-09-27 | 2026-06-25 |
| Motor Function Efficacy of Pharmacological Treatments Targeting Energy Metabolism, in Parkinson's Patients Terazosin - Parkinson Disease, Gait Analysis | Phase 4 | Unknown | I.R.C.C.S. Fondazione Santa Lucia | 50 | 2023-12-01 | 2023-09-22 |
| Improvement of Motor Imaginative Ability Through Functional Electrical Stimulation FESIA GRASP, VIRTUAL REHAB, GLOBUS ELITE - Electrode Site Reaction, Therapy, Directly Observed | Early Phase 1 | Completed | Universidad de Burgos | 81 | 2023-10-01 | 2024-02-28 |
| Acceptance and Commitment Therapy and Test Anxiety ACCEPTANCE AND COMMITMENT THERAPY-BASED PSYCOEDUCATION - Therapy, Directly Observed | Not applicable | Unknown | Artvin Coruh University | 60 | 2022-12-01 | 2023-01-05 |
| Nocardia Cell Wall Skeleton for the Treatment of Diabetic Foot Ulcer Wounds Nocardia rubra Cell Wall Skeleton, Silver ions dressing - Diabetic Foot Ulcer, Therapy, Directly Observed | Phase 4 | Unknown | The Affiliated Hospital of Xuzhou Medical University | 116 | 2022-05-20 | 2022-05-10 |
| Video-observed Therapy for Active Tuberculosis: a Feasibility Study Video-observed therapy (vDOT) - Tuberculosis Active | Not applicable | Completed | Ligue Pulmonaire Genevoise | 51 | 2021-11-26 | 2025-09-08 |
| Supporting Treatment Outcomes Among PWID Low intensity HCV treatment adherence support, Medium intensity HCV treatment adherence support, High intensity HCV treatment adherence support - Hepatitis C, HIV Coinfection | Not applicable | Completed | Johns Hopkins University | 3000 | 2021-01-21 | 2025-04-08 |
| Electronic Pillbox-enabled SAT Versus DOT for TB Medication Adherence and Treatment Outcomes MERM-observed self-administered therapy - Tuberculosis | Not applicable | Completed | Addis Ababa University | 114 | 2020-06-01 | 2022-07-12 |
| Trial of Adherence App for Buprenorphine Treatment (TAAB) Study Video-based DOT Application - Opioid-Related Disorders | Not applicable | Completed | University of Washington | 78 | 2019-02-15 | 2021-10-06 |
| A Trial of Directly Observed and Long-term Varenicline Long-Term Varenicline, Short-Term Varenicline, Directly Observed Therapy - Tobacco Use Disorder, Opioid-use Disorder | Phase 4 | Completed | Albert Einstein College of Medicine | 243 | 2018-10-25 | 2024-08-30 |
| Role of Pegylated Interferon in Combination With DAAs to Cure Hepatitis C As Soon As Possible - Hepatitis C [ASAP-C] Sofosbuvir, Daclatasvir, Pegylated Interferon alfa-2a - Hepatitis C, Chronic | Phase 2 / Phase 3 | Completed | Johns Hopkins Bloomberg School of Public Health | 150 | 2018-02-02 | 2021-05-18 |
| Smartphone Based aDOT Treatment With Fixed-Dose Elbasvir and Grazoprevir in PWIDs AiCure, AiCure with gamification - Hepatitis C, Medication Adherence | Not applicable | Completed | Albert Einstein College of Medicine | 11 | 2017-11-14 | 2021-09-14 |
| An Evaluation of Traditional Directly Observed Therapy (DOT) and Electronic DOT for TB Treatment Electronic DOT, In-person DOT - Tuberculosis, Drug-resistant Tuberculosis | Not applicable | Completed | Centers for Disease Control and Prevention | 216 | 2017-07-19 | 2026-07-02 |
| Patient-Centered Models of HCV Care for People Who Inject Drugs Patient Navigation, modified Directly Observed Therapy - Hepatitis C, Medication Adherence | Not applicable | Completed | Prisma Health-Upstate | 755 | 2016-09-15 | 2024-09-26 |
| Using Artificial Intelligence To Monitor Medication Adherence in Opioid Replacement Therapy AiCure monitoring and intervention - Opiate Addiction, Medication Non-adherence | Not applicable | Completed | AiCure | 9 | 2016-08-01 | 2017-09-12 |
| VDOT for Monitoring Adherence to LTBI Treatment Video Directly Observed Therapy, In-Person DOT - Tuberculosis, Latent Tuberculosis Infection | Not applicable | Completed | University of California, San Diego | 129 | 2016-03-08 | 2021-02-05 |
| Cytoreductive Prostatectomy Combined With Triple or Dual Systemic Therapy in mHSPC Patients Cytoreductive prostatectomy or brachytherapy, ADT+second-generation antiandrogens ± chemotherapy - Metastatic Prostate Cancer, Therapy, Directly Observed | Phase 3 | Recruiting | The First Affiliated Hospital with Nanjing Medical University | 200 | 2016-01-01 | 2024-04-05 |
| Emtricitabine/Tenofovir Alafenamide as Salvage ART FTC/TAF - HIV | Phase 2 | Terminated | National Institute of Allergy and Infectious Diseases (NIAID) | 1 | 2015-09-16 | 2017-11-14 |
Showing 20 of 34. Sign in to see all of them.
HIV Infections (8) · Tuberculosis (7) · Patient Compliance (6) · Hepatitis C, Chronic (5) · Medication Adherence (5) · Behavior, Addictive (4) · Hepatitis C (4) · Liver Diseases (3) · Opioid-Related Disorders (3) · Acquired Immunodeficiency Syndrome (2) · Reinfection (2) · Asthma (1) · Bipolar Disorder (1) · Depression (1)
Behavior (34) · Health Behavior (34) · Patient Acceptance of Health Care (34) · Treatment Adherence and Compliance (33) · Medication Adherence (29) · Patient Compliance (28) · Infections (19) · Blood-Borne Infections (14) · Communicable Diseases (14) · RNA Virus Infections (14) · Virus Diseases (13) · Immune System Diseases (11) · Genital Diseases (10) · Urogenital Diseases (10) · Immunologic Deficiency Syndromes (9)
Emtricitabine (2) · Sofosbuvir (2) · peginterferon alfa-2a (2) · Brachytherapy (1) · Control Groups (1) · Didanosine (1) · Drug Therapy (1) · Emotion-Focused Therapy (1) · Fluoxetine (1) · Food (1) · Lamivudine (1) · Lisosan G (1) · Lopinavir (1) · Methods (1) · Patient Navigation (1)
National Institute of Allergy and Infectious Diseases (NIAID) (4) · AiCure (2) · Albert Einstein College of Medicine (2) · Johns Hopkins Bloomberg School of Public Health (2) · Johns Hopkins University (2) · Prisma Health-Upstate (2) · Universidad de Burgos (2) · Addis Ababa University (1) · Artvin Coruh University (1) · Centers for Disease Control and Prevention (1) · Hospital de Clinicas de Porto Alegre (1) · I.R.C.C.S. Fondazione Santa Lucia (1) · Ligue Pulmonaire Genevoise (1) · Massachusetts General Hospital (1) · Menzies School of Health Research (1)
United States (16) · India (3) · South Africa (3) · Turkey (Türkiye) (2) · Armenia (1) · Australia (1) · Brazil (1) · China (1) · Ethiopia (1) · France (1) · Puerto Rico (1) · Spain (1) · Switzerland (1)
Adam Hanina, MBA (1) · Adam Hanina, MBA, MPhil (1) · Aditya Gaur, MD (1) · Alain Litwin, MD (1) · Alain Litwin, MD, MPH (1) · Alice Pau, Pharm.D. (1) · Antonella Peppe, MD, PhD (1) · Charles Flexner, MD (1) · Daniel Labovitz, MD (1) · David R. Bangsberg, MD, MPH (1) · Donna Mildvan, MD (1) · Frederick L Altice, M.D. (1) · Garland Gudger, MD, MPH (1) · Gerald H Friedland (1)
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R01DA026727 (2), D43TW009127 (1), R01AI055359 (1), R01AI145555 (1), R01DA013805 (1), R01DA034086 (1), R01DA042813 (1), R01MD018384 (1), R01MH063011 (1), R44DA044053 (1)