4 completed, 3 terminated. 7 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 4, Terminated 3 |
| Phase 3 | 1 | Completed 1 |
Follow Directly Observed Therapy: new trials by email Literature Review of Directly Observed Therapy trials Research Report on Directly Observed Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Role of Pegylated Interferon in Combination With DAAs to Cure Hepatitis C As Soon As Possible - Hepatitis C [ASAP-C] Sofosbuvir, Daclatasvir, Pegylated Interferon alfa-2a - Hepatitis C, Chronic | Phase 2 / Phase 3 | Completed | Johns Hopkins Bloomberg School of Public Health | 150 | 2018-02-02 | 2021-05-18 |
| Emtricitabine/Tenofovir Alafenamide as Salvage ART FTC/TAF - HIV | Phase 2 | Terminated | National Institute of Allergy and Infectious Diseases (NIAID) | 1 | 2015-09-16 | 2017-11-14 |
| Directly Observed Therapy for HCV in Chennai, India Sofosbuvir, Pegylated Interferon alfa-2a, Ribavirin - Hepatitis C, Chronic | Phase 2 | Completed | Johns Hopkins Bloomberg School of Public Health | 50 | 2015-09-01 | 2021-04-15 |
| Helping HIV Infected Patients in South Africa Adhere to Drug Regimens Directly Observed Therapy - HIV Infections | Phase 2 | Terminated | Johns Hopkins University | 274 | 2005-02-01 | 2015-03-27 |
| APAD2: Effects of Rehabilitation Programme in Adapted Physical Activity (APA) Among Type 2 Diabetics Rehabilitation programme in Adapted Physical Activity (APA), Therapeutic education primarily focused on dietary - NIDDM | Phase 2 | Terminated | University Hospital, Grenoble | 10 | 2004-11-01 | 2013-06-19 |
| Antidepressant Medication Plus Directly Observed Therapy for Improving Adherence to Antiretroviral Therapy Directly Observed Therapy (DOT), Fluoxetine - HIV Infections, Depression | Phase 2 | Completed | Massachusetts General Hospital | 150 | 2001-01-01 | 2013-11-15 |
| A Study to Compare Anti-HIV Drugs Given Twice a Day or Once a Day, With or Without Direct Observation lopinavir/ritonavir, emtricitabine, stavudine - HIV Infections | Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 402 | 2021-11-01 |
HIV Infections (3) · Hepatitis C, Chronic (2) · Acquired Immunodeficiency Syndrome (1) · Depression (1) · Diabetes Mellitus, Type 2 (1) · Motor Activity (1)
Behavior (7) · Health Behavior (7) · Medication Adherence (7) · Patient Acceptance of Health Care (7) · Patient Compliance (7) · Treatment Adherence and Compliance (7) · Blood-Borne Infections (5) · Communicable Diseases (5) · Infections (5) · RNA Virus Infections (5) · Virus Diseases (5) · Genital Diseases (3) · Immune System Diseases (3) · Immunologic Deficiency Syndromes (3) · Lentivirus Infections (3)
Emtricitabine (2) · Sofosbuvir (2) · peginterferon alfa-2a (2) · Fluoxetine (1) · Lopinavir (1) · Ribavirin (1) · Stavudine (1) · Tenofovir (1) · daclatasvir (1) · tenofovir alafenamide (1)
Johns Hopkins Bloomberg School of Public Health (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · Johns Hopkins University (1) · Massachusetts General Hospital (1) · University Hospital, Grenoble (1)
United States (3) · India (2) · South Africa (2) · France (1) · Puerto Rico (1)
Alice Pau, Pharm.D. (1) · Charles Flexner, MD (1) · David R. Bangsberg, MD, MPH (1) · Donna Mildvan, MD (1) · Richard E Chaisson, MD (1) · Shruti Mehta, PhD, MPH (1) · Sunil S Solomon, MBBS, PhD, MPH (1)
PMID 11852377, PMID 12037511, PMID 12448827, PMID 12746623, PMID 12846028, PMID 19597072, PMID 20192725, PMID 20453627, PMID 27590273, PMID 28719029
R01DA026727 (2), R01AI055359 (1), R01MH063011 (1)