7 completed, 3 terminated, 3 unknown. 13 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 13 | Completed 7, Terminated 3, Unknown 3 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
Follow Diabetic Foot Ulcers: new trials by email Literature Review of Diabetic Foot Ulcers trials Research Report on Diabetic Foot Ulcers
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Platelet-Rich Plasma-Fibrin Glue in Combination With Vitamin E and C for Treatment of Non-healing Diabetic Foot Ulcers PRP-Fibrin Glue, Vitamin E and C, Placebo - Diabetic Foot Ulcers, Diabetic Wound | Phase 2 / Phase 3 | Unknown | Mashhad University of Medical Sciences | 24 | 2019-08-28 | 2020-03-20 |
| A Study of Granexin Gel in the Treatment of Diabetic Foot Ulcer Granexin gel, Vehicle gel - Diabetic Foot Ulcers | Phase 3 | Terminated | Xequel Bio, Inc. | 124 | 2018-11-21 | 2020-05-29 |
| Efficacy of the Combination of Isosorbide Dinitrate Spray and Chitosan in Diabetic Foot Ulcers Chitosan, Isosorbide dinitrate, Placebo - Diabetic Foot Ulcers | Phase 3 | Completed | University of Guadalajara | 68 | 2015-06-01 | 2021-01-12 |
| Clinical Efficacy of Platelet Gel From Cord Blood for the Treatment of Diabetic Foot Ulcers Allogeneic cord blood platelet gel-CBPG, Standard Local Medications-SLM - Diabetic Foot Ulcers | Phase 3 | Completed | Centro Nazionale Sangue | 50 | 2015-01-01 | 2017-07-21 |
| Effect of Topic Pirfenidone in Diabetic Ulcers Pirfenidone, Debridement - Diabetic Foot Ulcers | Phase 3 | Completed | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | 36 | 2013-10-01 | 2016-02-15 |
| Phase 3 Study Evaluating Efficacy and Safety of DSC127 Compared With Vehicle and With Standard-of-care in Diabetic Foot Ulcers DSC127, placebo vehicle gel, Standard of Care gel, Aquasite - Diabetic Foot Ulcers | Phase 3 | Terminated | Integra LifeSciences Corporation | 396 | 2013-04-01 | 2017-12-12 |
| A Comparison of the dermaPACE® (Pulsed Acoustic Cellular Expression) Device in Conjunction With Standard of Care Versus Standard of Care Alone in the Treatment of Diabetic Foot Ulcers Electrohydraulic-generated shock wave, Sham device plus standard of care - Diabetic Foot Ulcers | Phase 3 | Unknown | SANUWAVE, Inc. | 90 | 2013-03-01 | 2014-03-06 |
| Phase III Study to Evaluate Efficacy and Safety of DSC127 in Diabetic Foot Ulcers DSC127, placebo vehicle gel - Diabetic Foot Ulcers | Phase 3 | Terminated | Integra LifeSciences Corporation | 266 | 2013-02-01 | 2017-12-12 |
| Transdermal Continuous Oxygen Therapy for Diabetic Foot Ulcers Epiflo, Moist Wound Therapy - Diabetic Foot Ulcers | Phase 2 / Phase 3 | Completed | Neogenix, LLC dba Ogenix | 130 | 2009-10-01 | 2014-05-13 |
| Monochromatic Phototherapy on Diabetic Foot Ulcers Monochromatic phototherapy, Biolight®, Monochromatic phototherapy - Diabetic Foot Ulcers | Phase 3 | Unknown | Biolight AB | 107 | 2008-08-01 | 2011-06-08 |
| Effectiveness of dermaPACE™ Device and Standard Treatment Compared to Standard Treatment Alone for Diabetic Foot Ulcers acoustical pulse energy (extracorporeal shockwave), Sham - Diabetic Foot Ulcers | Phase 3 | Completed | SANUWAVE, Inc. | 206 | 2007-10-01 | 2014-04-14 |
| MSI-78 Topical Cream vs. Oral Ofloxacin in the Treatment of Infected Diabetic Ulcers ofloxacin, MSI-78 - Diabetic Foot Ulcers | Phase 3 | Completed | Abeona Therapeutics, Inc | 584 | 1994-08-01 | 2020-09-03 |
| MSI-78 Topical Cream vs. Oral Ofloxacin in the Treatment of Infected Diabetic Ulcers ofloxacin, MSI-78 - Diabetic Foot Ulcers | Phase 3 | Completed | Abeona Therapeutics, Inc | 342 | 1994-08-01 | 2020-09-03 |
Diabetic Foot (13) · Diabetes Mellitus (4) · Ulcer (4) · Diabetes Complications (1) · Wounds and Injuries (1)
Cardiovascular Diseases (13) · Diabetic Angiopathies (13) · Diabetic Neuropathies (13) · Endocrine System Diseases (13) · Foot Ulcer (13) · Leg Ulcer (13) · Skin Diseases (13) · Skin Ulcer (13) · Skin and Connective Tissue Diseases (13) · Vascular Diseases (13) · Diabetes Complications (12) · Diabetes Mellitus (9) · Glucose Metabolism Disorders (4) · Metabolic Diseases (4) · Nutritional and Metabolic Diseases (4)
Ofloxacin (2) · aclerastide (2) · pexiganan (2) · Chitosan (1) · Debridement (1) · Glutathione Transferase (1) · Isosorbide Dinitrate (1) · Polymers (1) · Vitamin E (1) · pirfenidone (1) · salicylhydroxamic acid (1)
Abeona Therapeutics, Inc (2) · Integra LifeSciences Corporation (2) · SANUWAVE, Inc. (2) · Biolight AB (1) · Centro Nazionale Sangue (1) · Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran (1) · Mashhad University of Medical Sciences (1) · Neogenix, LLC dba Ogenix (1) · University of Guadalajara (1) · Xequel Bio, Inc. (1)
United States (8) · Canada (3) · Germany (1) · Hungary (1) · India (1) · Iran (1) · Italy (1) · Mexico (1) · Poland (1) · Puerto Rico (1) · South Africa (1) · Spain (1) · Sweden (1) · United Kingdom (1)
Paul Litka, MD (2) · Alan Dunton, MD (1) · Daniel Jorgensen, MD (1) · Daryoush Hamidi Alamdari, Ph.D (1) · Francisco J Gomez-Perez, MD (1) · Jan Apelqvist, M.D., Ph.D. (1) · Leonel Garcia, PhD (1) · Maurizio Marconi, MD (1) · Simonetta Pupella, MD (1) · Vickie R Driver, MSDPM FACFAS (1)
PMID 18990064, PMID 18601587, PMID 19064169, PMID 19128245, PMID 19152653, PMID 19170984, PMID 19424751, PMID 20873963, PMID 23736928, PMID 2403699, PMID 33646060, PMID 3753059