2 terminated, 1 completed, 1 unknown. 4 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 4 | Terminated 2, Completed 1, Unknown 1 |
Follow Critical Limb Ischemia (CLI): new trials by email Literature Review of Critical Limb Ischemia (CLI) trials Research Report on Critical Limb Ischemia (CLI)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy, Tolerability and Safety of Intramuscular Injections of PLX PAD for the Treatment of Subjects With Critical Limb Ischemia (CLI) With Minor Tissue Loss Who Are Unsuitable for Revascularization PLX-PAD, Placebo - Critical Limb Ischemia (CLI) | Phase 3 | Completed | Pluristem Ltd. | 213 | 2017-05-22 | 2024-08-30 |
| The Efficacy and Safety of REX-001 to Treat Ischemic Ulcers in Subjects With CLI Rutherford Category 5 and DM REX-001, Placebo - Peripheral Arterial Disease (PAD), Diabetes Mellitus (DM) | Phase 3 | Terminated | Ixaka Ltd | 49 | 2017-04-25 | 2023-03-16 |
| The Efficacy and Safety of REX-001 to Treat Ischemic Rest Pain in Subjects With CLI Rutherford Category 4 and DM REX-001, Placebo - Peripheral Arterial Disease (PAD), Diabetes Mellitus (DM) | Phase 3 | Terminated | Ixaka Ltd | 3 | 2017-04-05 | 2021-05-07 |
| Critical Limb Ischemia Rapid Delivery by SurgWerks-CLI Kit and VXP System Autologous Bone Marrow Concentrate (aBMC), Placebo Control (diluted autologous peripheral blood) - Critical Limb Ischemia (CLI) | Phase 3 | Unknown | Cesca Therapeutics, Inc. | 224 | 2017-01-01 | 2016-07-28 |
Chronic Limb-Threatening Ischemia (4) · Cardiovascular Diseases (2) · Diabetes Mellitus (2) · Diabetes Mellitus, Type 1 (2) · Diabetes Mellitus, Type 2 (2) · Peripheral Arterial Disease (2)
Arterial Occlusive Diseases (4) · Arteriosclerosis (4) · Atherosclerosis (4) · Chronic Disease (4) · Disease Attributes (4) · Ischemia (4) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Peripheral Vascular Diseases (4) · Vascular Diseases (4) · Autoimmune Diseases (2) · Cardiovascular Diseases (2) · Endocrine System Diseases (2) · Glucose Metabolism Disorders (2) · Immune System Diseases (2)
Ixaka Ltd (2) · Cesca Therapeutics, Inc. (1) · Pluristem Ltd. (1)
Czechia (3) · Hungary (3) · Germany (2) · Poland (2) · Portugal (2) · Spain (2) · United Kingdom (2) · Bulgaria (1) · Israel (1) · Netherlands (1) · North Macedonia (1) · United States (1)
Gilbert Wagener, MD (2) · Dalip Sethi, PhD (1)