6 completed. 6 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 6 |
| Phase 2 | 1 | Completed 1 |
Follow COPD Exacerbation: new trials by email Literature Review of COPD Exacerbation trials Research Report on COPD Exacerbation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study Comparing Efficacy, Safety and Tolerability of the Fixed Dose Triple Combination CHF 5993 With the Fixed Dose Dual Combination CHF 1535 in Subjects With COPD Beclomethasone Dipropionate, Glycopyrronium Bromide, Formoterol Fumarate - COPD, COPD Exacerbation | Phase 3 | Completed | Chiesi Farmaceutici S.p.A. | 3406 | 2022-04-27 | 2026-09-21 |
| Effectiveness of Low-Dose Theophylline for the Management of Biomass-Associated COPD Theophylline ER, Placebo oral tablet, Standard of Care Treatment - COPD, COPD Exacerbation | Phase 3 | Completed | University of Miami | 100 | 2021-02-23 | 2024-11-15 |
| Efficacy of Varenicline on Smoking Cessation at the Acute Phase of an Exacerbation of Chronic Obstructive Pulmonary Disease Varenicline, placebo - Chronic Obstructive Pulmonary Disease, COPD Exacerbation | Phase 3 | Completed | University Hospital, Brest | 83 | 2012-08-01 | 2016-02-11 |
| Oral Prednisolone in Severe Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) Prednisolone, usual care - COPD Exacerbation | Phase 3 | Completed | Fekri Abroug | 317 | 2010-04-01 | 2017-08-01 |
| TNF-alpha Antagonists for AECOPD: A Randomized, Double-Blind, Placebo-Controlled Pilot Trial Prednisone, Etanercept, levofloxacin - COPD Exacerbation | Phase 2 / Phase 3 | Completed | Ottawa Hospital Research Institute | 81 | 2008-11-01 | 2016-04-11 |
| Magnesium Sulfate Versus Ipratropuim Bromide in Acute Exacerbation of Chronic Obstructive Pulmonary Disease Ipratropium bromide, Magnesium Sulfate - COPD Exacerbation | Phase 3 | Completed | University of Monastir | 124 | 2005-01-01 | 2010-06-03 |
Pulmonary Disease, Chronic Obstructive (4) · Smoking (1) · Smoking Cessation (1)
Chronic Disease (4) · Disease Attributes (4) · Lung Diseases (4) · Lung Diseases, Obstructive (4) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Respiratory Tract Diseases (4) · Behavior (1) · Health Behavior (1)
Beclomethasone (1) · Etanercept (1) · Formoterol Fumarate (1) · Glycopyrrolate (1) · Ipratropium (1) · Levofloxacin (1) · Magnesium Sulfate (1) · Prednisolone (1) · Prednisone (1) · Theophylline (1) · Varenicline (1)
Chiesi Farmaceutici S.p.A. (1) · Fekri Abroug (1) · Ottawa Hospital Research Institute (1) · University Hospital, Brest (1) · University of Miami (1) · University of Monastir (1)
Tunisia (2) · Argentina (1) · Bulgaria (1) · Canada (1) · Czechia (1) · France (1) · Hungary (1) · Mexico (1) · Poland (1) · Puerto Rico (1) · Romania (1) · Uganda (1) · United States (1)
Fekri Abroug, MD (1) · Shawn Aaron, MD, MSc (1) · Thomas Siler, MD (1) · Trishul Siddharthan, MD (1)
PMID 23161645, PMID 31854207, PMID 33726828, PMID 34611902
2023 (1), K23HL146946 (1)