14 completed, 3 unknown, 2 withdrawn, 1 terminated. 10 Not applicable, 3 Phase 4, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 9, Withdrawn 1 |
| Phase 4 | 3 | Completed 1, Terminated 1, Withdrawn 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Contact Lens Complication: new trials by email Literature Review of Contact Lens Complication trials Research Report on Contact Lens Complication
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Impact of Soft Contact Lenses on the Corneal Neuromediators and Optical Quality in High Myopia Prior to SMILE This study does not involve any interventions - Contact Lens Complication | Completed | yuhao shao | 80 | 2024-10-18 | 2026-10-20 | |
| Cyclosporine and Intense Pulsed Light for Dry Eye in Contact Lens Users CycloSPORINE Ophthalmic, Intense Pulsed Light, Sham Intense Pulse Light - Dry Eye, Contact Lens Complication | Phase 3 | Unknown | Université de Sherbrooke | 44 | 2024-04-25 | 2024-05-01 |
| Total30 For Contact Lens Dropouts T30 Contact lenses - Dry Eye, Contact Lens Complication | Not applicable | Completed | Southern College of Optometry | 60 | 2024-04-23 | 2025-12-03 |
| T30 for Astigmatism in Digital Device Users Total30 for Astigmatism Contact Lenses - Contact Lens Complication, Astigmatism | Not applicable | Completed | Southern College of Optometry | 48 | 2024-03-15 | 2025-02-24 |
| Total30 for Astigmatism Contact Lenses TOTAL30 for Astigmatism Contact Lenses - Contact Lens Complication, Astigmatism | Not applicable | Completed | Southern College of Optometry | 48 | 2023-10-15 | 2025-02-24 |
| Long-term Effects of SCL-wearing on Corneal Neuromediators and Postoperative Rehabilitation After SMILE Contact Lens Complication, Small Incision Lenticule Extraction | Completed | yuhao shao | 90 | 2023-06-01 | 2025-07-20 | |
| Evaluation of the Safety and Efficacy of Rigid Breathable Scleral Contact Lenses for the Correction of Ametropia Ocular Surface Disease, Irregular Astigmatism | Unknown | Tianjin Eye Hospital | 176 | 2022-11-01 | 2024-02-13 | |
| Effects of Supplementation With PUFAs and Antioxidants for Contact Lens Discomfort HydroEye® - Dry Eye, Contact Lens Complication | Phase 4 | Terminated | University of Alabama at Birmingham | 31 | 2022-09-16 | 2025-03-06 |
| Dailies Total 1 Sphere Contact Lenses DT1 Sphere Contact Lenses - Dry Eye, Contact Lens Complication | Not applicable | Completed | University of Alabama at Birmingham | 60 | 2022-05-23 | 2024-10-01 |
| Efficacy of "Aquoral Lipo" Artificial Tears in Contact Lens Wearers With Discomfort Aquoral Lipo (Esteve), Hyabak (Thea) - Contact Lens Complication | Not applicable | Completed | Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA | 41 | 2022-03-01 | 2024-10-08 |
| Total30 Sphere Contact Lenses Total30 Sphere Contact Lenses - Contact Lens Complication, Dry Eye | Not applicable | Completed | University of Alabama at Birmingham | 48 | 2022-01-03 | 2022-12-16 |
| Observational Study on the Efficacy and Tolerance of EYEBRID Lenses EyeBrid Excel hybrid lenses - Contact Lens Complication | Unknown | University Hospital, Caen | 60 | 2021-09-30 | 2021-09-08 | |
| Correlation Study of Corneal Nerve Changes and Dry Eye in Contact Lens Wearers contact lens - Contact Lens Complication, Dry Eye | Completed | Peking University Third Hospital | 60 | 2020-10-01 | 2022-06-01 | |
| Direct Application of Systane Complete to Contact Lenses Systane Complete, Sensitive Eyes Rewetting Drops - Dry Eye, Contact Lens Complication | Phase 4 | Completed | University of Alabama at Birmingham | 73 | 2019-05-28 | 2020-10-08 |
| Effects of Xiidra on Closed Eye Tear Film Leukocytes in Dry Eye Disease Lifitegrast - Ocular Discomfort, Ocular Inflammation | Phase 4 | Withdrawn | University of Alabama at Birmingham | 2019-01-01 | 2019-05-17 | |
| Treating Contact Lens Discomfort With Orthokeratology Orthokeratology - Dry Eye, Contact Lens Complication | Not applicable | Completed | University of Alabama at Birmingham | 46 | 2018-08-07 | 2020-08-17 |
| Evaluation of Contact Lens Saline Solutions With Scleral GP Contact Lens Wearers Experiencing Fogging Saline Solution Enriched, Saline Rinse Solution - Contact Lens Complication, Debris in Post Lens Tear Reservoir | Not applicable | Completed | Contamac Ltd | 36 | 2018-04-09 | 2021-01-27 |
| Soft Contacts Observation of Risk and Education (SCORE) No intervention - Contact Lens Complication, Contact Lens Acute Red Eye | Completed | Southern California College of Optometry at Marshall B. Ketchum University | 171 | 2017-12-30 | 2019-09-18 | |
| A Clinical Study Comparing the Comfort of Three Commercially Available Contact Lenses Acuvue® Oasys® Lenses (senofilcon A), 30-Day Bausch + Lomb PureVision (balafilcon A), Clariti® 1-Day (Somofilcon A) - Contact Lens Complication | Not applicable | Withdrawn | ORA, Inc. | 2014-08-01 | 2024-04-25 | |
| Myopia Control With Orthokeratology Contact Lenses in Spain Menicon Z Night, Control - Myopia, Progressive, Children, Only | Not applicable | Completed | Menicon Co., Ltd. | 69 | 2007-03-01 | 2021-03-26 |
Dry Eye Syndromes (9) · Astigmatism (3) · Refractive Errors (2) · Keratoconjunctivitis Sicca (1) · Myopia, Degenerative (1)
Eye Diseases (13) · Lacrimal Apparatus Diseases (9) · Refractive Errors (2) · Conjunctival Diseases (1) · Conjunctivitis (1) · Corneal Diseases (1) · Keratitis (1) · Keratoconjunctivitis (1) · Myopia (1)
Contact Lenses (1) · Cyclosporins (1) · Hyaluronic Acid (1) · Intense Pulsed Light Therapy (1) · Liposomes (1) · crocin (1) · hylan (1) · lifitegrast (1)
University of Alabama at Birmingham (6) · Southern College of Optometry (3) · yuhao shao (2) · Contamac Ltd (1) · Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA (1) · Menicon Co., Ltd. (1) · ORA, Inc. (1) · Peking University Third Hospital (1) · Southern California College of Optometry at Marshall B. Ketchum University (1) · Tianjin Eye Hospital (1) · University Hospital, Caen (1) · Université de Sherbrooke (1)
United States (11) · China (4) · Canada (2) · France (1) · Spain (1)
Andrew D Pucker, OD, MS, PhD (1) · Andrew D Pucker, OD, PhD (1) · Bret Andre, MS, ABOe (1) · Dawn Lam (1) · Eric Lortie-Milner, OD (1) · Kelly K Nichols, OD MPH PhD (1) · Kelly K Nichols, OD, PhD (1) · Langis Michaud, OD, MSc (1) · Patrick Boissy, PhD (1) · Yan Wang, Prof (1)
PMID 22729437, PMID 22773180, PMID 23392299, PMID 32097182, PMID 39713278, PMID 41654845