9 completed, 5 not yet recruiting, 5 recruiting, 1 active not recruiting. 11 Not applicable, 9 Phase 4, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 7, Recruiting 3, Active not recruiting 1 |
| Phase 4 | 9 | Not yet recruiting 5, Completed 2, Recruiting 2 |
| Phase 1 | 1 | Withdrawn 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaporative Dry Eye acoltremon 0.003%. - Dry Eye, Evaporative Dry Eye | Phase 4 | Not yet recruiting | Southern College of Optometry | 41 | 2026-10-26 | 2026-10-28 |
| Contact Lens-Wearing Dry Eye Subjects Who Are Treated With Acoltremon 0.003% acoltremon 0.003% - Dry Eye, Contact Lens Discomfort | Phase 4 | Not yet recruiting | Eye Research Associates, LLC | 50 | 2026-10-10 | 2026-10-08 |
| Switching From Preserved Glaucoma Therapy to Preservative-Free ZOLYMBUS preservative free ZOLYMBUS™ 0.01%. - Eye Drops Self-instillation, Glaucoma | Phase 4 | Not yet recruiting | Southern College of Optometry | 40 | 2026-10-05 | 2026-09-28 |
| Evaluating Altius Tinted Contact Lenses as an Option Managing for Post-Concussion Visual Syndrome ALTIUS® daily disposable performance-tinted contact lenses - Post Concussion Symptoms | Not applicable | Completed | Southern College of Optometry | 10 | 2026-05-27 | 2026-10-13 |
| P1 Toric Vs. Max 1day , silicone hydrogel (lehfilcon A) soft contact lens (CL) with SMARTSURFACE Technology and UV protection - Eye, Astigmatism | Not applicable | Active not recruiting | Southern College of Optometry | 32 | 2026-05-27 | 2026-11-04 |
| Clinical Performance of Verofilcon A Toric Contact Lenses Total 30 multi foric contact lenses - Contact Lenses, Presbyopia | Not applicable | Recruiting | Southern College of Optometry | 32 | 2026-04-01 | 2026-05-14 |
| Effects of Acute Sugar Intake on Choroidal Thickness Oral glucose - Choroid | Not applicable | Recruiting | Southern College of Optometry | 47 | 2026-01-01 | 2026-01-29 |
| Switching From Xiidra to TRYPTYR acoltremon 0.003% - Dry Eye, Dry Eyes Chronic | Phase 4 | Not yet recruiting | Southern College of Optometry | 100 | 2025-12-15 | 2025-12-05 |
| Switching From Restasis to TRYPTYR acoltremon 0.003% - Dry Eye, Eye Diseases | Phase 4 | Not yet recruiting | Southern College of Optometry | 100 | 2025-12-01 | 2025-12-05 |
| Impact of TRYPTYR on a Patient's Quality of Life and Ability to Perform Work Acoltremon - Dry Eye, Eye Diseases | Phase 4 | Recruiting | Southern College of Optometry | 40 | 2025-11-01 | 2025-12-05 |
| Quality of Life in Presbyopic Patients Who Are Treated With Qlosi pilocarpine HCL ophthalmic solution - Presbyopia, Glasses | Phase 4 | Recruiting | Southern College of Optometry | 36 | 2025-07-18 | 2025-08-12 |
| Comparison of Two Contact Lens Designs Stenfilcon A contact lens designs with and without Digital Boost technology that incorporate a 0.3D add power into the lens - Computer Vision Syndrome, Accommodation | Not applicable | Completed | Southern College of Optometry | 30 | 2025-05-22 | 2026-03-25 |
| Acuvue Oaysis Contact Lens Wearers Being Refit Into P7 Contact Lenses Precision 7 contact lenses - Contact Lens Comfort | Not applicable | Recruiting | Southern College of Optometry | 40 | 2025-04-15 | 2025-11-26 |
| How Does DT1 Sphere Perform in Current and Successful Acuvue MAX Wearers? Dailies total 1 contact lenses - Contact Lens Comfort and Successful Refitting | Not applicable | Completed | Southern College of Optometry | 36 | 2024-07-15 | 2025-08-12 |
| Treating Lid Wiper Epitheliopathy Preservative Free eye drop - Dry Eye, Visual Acuity | Phase 4 | Completed | Southern College of Optometry | 52 | 2024-05-27 | 2025-02-25 |
| Higher Order Aberration and Relationship With Soft Contact Lens Modulus OVITZ xwave aberrometer - Corneal Wavefront Aberration | Unknown | Southern College of Optometry | 100 | 2024-05-20 | 2024-05-22 | |
| Total30 For Contact Lens Dropouts T30 Contact lenses - Dry Eye, Contact Lens Complication | Not applicable | Completed | Southern College of Optometry | 60 | 2024-04-23 | 2025-12-03 |
| T30 for Astigmatism in Digital Device Users Total30 for Astigmatism Contact Lenses - Contact Lens Complication, Astigmatism | Not applicable | Completed | Southern College of Optometry | 48 | 2024-03-15 | 2025-02-24 |
| Delaying the Onset of Nearsightedness Until Treatment Study Atropine Ophthalmic - Myopia | Phase 1 | Withdrawn | Ohio State University | 2024-01-01 | 2024-04-16 | |
| Total30 for Astigmatism Contact Lenses TOTAL30 for Astigmatism Contact Lenses - Contact Lens Complication, Astigmatism | Not applicable | Completed | Southern College of Optometry | 48 | 2023-10-15 | 2025-02-24 |
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Dry Eye Syndromes (10) · Astigmatism (3) · Eye Diseases (3) · Presbyopia (2) · Refractive Errors (2) · Corneal Wavefront Aberration (1) · Glaucoma (1) · Myopia (1) · Post-Concussion Syndrome (1)
Contact Lenses, Hydrophilic (1) · Glucose (1) · Orthoptics (1)
United States (16)
Angela Chen, OD, MS (1) · Chris Lievens (1) · Jeffrey J Walline, OD PhD (1)