7 completed, 5 unknown, 3 terminated, 1 not yet recruiting. 9 Not applicable, 2 Phase 2, 2 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Completed 6, Unknown 2, Withdrawn 1 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
| Phase 3 | 2 | Terminated 2 |
| Phase 4 | 1 | Unknown 1 |
Follow Constipation-predominant Irritable Bowel Syndrome: new trials by email Literature Review of Constipation-predominant Irritable Bowel Syndrome trials Research Report on Constipation-predominant Irritable Bowel Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Soluble and Osmotic Fibre (SOLOS) Diet for Constipation Diet - Constipation, Constipation - Functional | Not yet recruiting | Singapore Institute of Technology | 180 | 2026-02-02 | 2026-02-06 | |
| To Study the Effect of Short-chain Fructooligosaccharides in Women With Irritable Bowel Syndrome Short Chain Fructooligosaccharides, Corn Starch - Irritable Bowel Syndrome, Diarrhea- Irritable Bowel Syndrome | Not applicable | Unknown | Universidad Autonoma de Chihuahua | 40 | 2024-12-02 | 2024-02-05 |
| MOWOOT Device Treatment for Adults With Chronic Constipation Intermittent Colonic Exoperistalsis with MOWOOT device, Standard of care with Trans-Anal Irrigation - Constipation - Functional, Constipation-predominant Irritable Bowel Syndrome | Not applicable | Completed | usMIMA S.L. | 86 | 2024-04-25 | 2026-06-03 |
| A Chinese Herbal Medicine for IBS-C CDD-2105, Placebo - Constipation-predominant Irritable Bowel Syndrome | Phase 2 | Unknown | Hong Kong Baptist University | 78 | 2024-03-25 | 2024-03-21 |
| Anorectal Manometry of Patients With Constipation Predominant IBS Constipation-predominant Irritable Bowel Syndrome | Unknown | Assiut University | 102 | 2023-07-01 | 2023-06-27 | |
| Laser Acupuncture on Irritable Bowel Syndrome in Females laser acupuncture - Constipation-predominant Irritable Bowel Syndrome | Not applicable | Unknown | Cairo University | 50 | 2023-03-01 | 2024-01-17 |
| The Impact of Aerobic Interval and Inspiratory Muscle Training On Patient Reported Outcome Scores In Individuals With Chronic Constipation Standard Physical Therapy Care, Aerobic and Inspiratory Muscle Training - Constipation, Constipation by Outlet Obstruction | Not applicable | Withdrawn | University of Miami | 2022-05-26 | 2023-05-12 | |
| Safety and Efficacy of Non-alcoholic Beverage Based on Kombucha in Patients With Constipations kombucha-based beverage - Irritable Bowel Syndrome With Constipation, Constipation-predominant Irritable Bowel Syndrome | Not applicable | Completed | Vasily Isakov | 40 | 2021-11-01 | 2023-09-06 |
| Efficacy of Linaclotide in Patients With Overlapping Functional Gastrointestinal Disorders Linaclotide, Lactulose, Omeprazol - Functional Dyspepsia, Constipation-predominant Irritable Bowel Syndrome | Phase 4 | Unknown | RenJi Hospital | 78 | 2021-01-01 | 2021-12-13 |
| Effect of taVNS on Abdominal Pain and Other Symptoms in Constipation-predominant Irritable Bowel Syndrome taVNS, sham-taVNS - Constipation-predominant Irritable Bowel Syndrome, Abdominal Pain | Not applicable | Completed | Tongji University | 42 | 2020-03-01 | 2022-05-31 |
| Assessment of Responsiveness to Treatment by Experience Sampling Method Constipation-predominant Irritable Bowel Syndrome | Terminated | Maastricht University Medical Center | 16 | 2018-01-01 | 2022-05-25 | |
| Effect of Saccharomyces Cerevisiae on the Improvement of Gastro-intestinal Disorders Associated to IBS With C Phenotype Saccharomyces cerevisiae CNCM I-3856, Placebo - Constipation-predominant Irritable Bowel Syndrome | Not applicable | Completed | Lesaffre International | 456 | 2017-03-20 | 2019-05-21 |
| Effect of Lubiprostone on Small Bowel Contractions in Female Patients With Constipation Irritable Bowel Syndrome (C-IBS) Lubiprostone, Placebo - Constipation-predominant Irritable Bowel Syndrome | Not applicable | Completed | Cedars-Sinai Medical Center | 4 | 2010-03-01 | 2011-12-12 |
| Neomycin and Rifaximin Plus Neomycin in Treating Methane Positive Constipation Predominant Irritable Bowel Syndrome Neomycin, Placebo, Rifaximin - Constipation-predominant Irritable Bowel Syndrome | Not applicable | Completed | Mark Pimentel, MD | 37 | 2009-08-01 | 2015-08-10 |
| Cheno Effect on Transit in Health and IBS-C Sodium chenodeoxycholate (NaCDC), Placebo - Constipation-predominant Irritable Bowel Syndrome | Phase 2 | Completed | Mayo Clinic | 36 | 2009-04-01 | 2012-07-02 |
| Randomized Trial of Mosapride Versus Placebo in the Treatment of Constipation-Predominant Irritable Bowel Syndrome Mosapride Citrate, Placebo - Constipation-Predominant Irritable Bowel Syndrome | Phase 3 | Terminated | American University of Beirut Medical Center | 41 | 2008-09-01 | 2013-04-09 |
| Long-Term Safety of Renzapride in Women With Constipation-Predominant Irritable Bowel Syndrome (IBS-C) Renzapride - Constipation-Predominant Irritable Bowel Syndrome | Phase 3 | Terminated | Alizyme | 939 | 2006-04-01 | 2008-07-08 |
Constipation (8) · Irritable Bowel Syndrome (3) · Abdominal Pain (2) · Ichthyosis Bullosa of Siemens (1)
Pathological Conditions, Signs and Symptoms (9) · Signs and Symptoms (9) · Signs and Symptoms, Digestive (9) · Colonic Diseases (3) · Colonic Diseases, Functional (3) · Digestive System Diseases (3) · Gastrointestinal Diseases (3) · Intestinal Diseases (3) · Neurologic Manifestations (2) · Pain (2) · Congenital Abnormalities (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Genetic Diseases, Inborn (1) · Ichthyosis (1) · Infant, Newborn, Diseases (1)
Chenodeoxycholic Acid (1) · Diet (1) · Inulin (1) · Lactulose (1) · Lubiprostone (1) · Neomycin (1) · Omeprazole (1) · Prebiotics (1) · Rifaximin (1) · Starch (1) · Vitamins (1) · itopride (1) · linaclotide (1) · mosapride (1) · renzapride (1)
Alizyme (1) · American University of Beirut Medical Center (1) · Assiut University (1) · Cairo University (1) · Cedars-Sinai Medical Center (1) · Hong Kong Baptist University (1) · Lesaffre International (1) · Maastricht University Medical Center (1) · Mark Pimentel, MD (1) · Mayo Clinic (1) · RenJi Hospital (1) · Singapore Institute of Technology (1) · Tongji University (1) · Universidad Autonoma de Chihuahua (1) · University of Miami (1)
United States (5) · China (2) · Egypt (1) · France (1) · Lebanon (1) · Netherlands (1) · Russia (1) · Singapore (1) · United Kingdom (1)
Ad AM Masclee, MD, PhD (1) · Ala' I. Sharara, MD (1) · Anthony Lembo, MD (1) · Bridgette J Wilson, Dr (1) · Edy E Soffer, MD (1) · Immaculada Herrero, PhD (1) · Lawrence Cahalin (1) · Mark Pimentel, MD, FRCP(C) (1) · Michael L. Camilleri, M.D. (1) · Nabil M. Mansour, MD (1) · Shengliang Chen (1)
PMID 20691689, PMID 25734736, PMID 27557052, PMID 34138761, PMID 35979259, PMID 36394933, PMID 38149073, PMID 40079184
1RC1DK086182 (1), R01DK054681 (1), R01DK079866 (1), UL1RR024150 (1)