22 unknown, 10 completed, 10 recruiting, 4 active not recruiting. 18 Not applicable, 4 Phase 2, 4 Phase 3, 2 Phase 4, 1 Early Phase 1.
Follow Circulating Tumor Cell: new trials by email Literature Review of Circulating Tumor Cell trials Research Report on Circulating Tumor Cell
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| CSF CTC-Capture-Guided EGFR-TKI and Bevacizumab Combination Therapy in EGFR-Mutant Advanced NSCLC Osimertinib 80 MG, Bevacizumab - Non Small Cell Lung Cancer, Circulating Tumor Cell | Early Phase 1 | Not yet recruiting | Second Affiliated Hospital of Nanchang University | 100 | 2024-08-20 | 2024-08-16 |
| Using a 3D Culture Model for Circulating Tumor Cells Combined With Molecular Bioassays in Patients With HNSCC Cancer Organoid 3D culture - Circulating Tumor Cell, HNSCC | Recruiting | Chang Gung Memorial Hospital | 88 | 2024-08-01 | 2025-01-01 | |
| A Trial to Evaluate the Effect of Applying Leukapheresis to Enrich CTCs in mPCa Patients leukapheresis - Prostate Cancer, Circulating Tumor Cell | Recruiting | RenJi Hospital | 50 | 2024-06-25 | 2026-08-11 | |
| Value of Dynamic Monitoring of Early Recurrence of Hepatocellular Carcinoma After Radical Resection Based on CTCS circulating tumor cells - Hepatocellular Carcinoma, Circulating Tumor Cell | Not yet recruiting | Zhujiang Hospital | 82 | 2024-04-01 | 2024-03-19 | |
| Liquid Biopsy (ctDNA) Guided Treatment in Localized Pancreatic Cancer: Neoadjuvant CTX vs. Upfront Surgery Neoadjuvant chemotherapy instead of upfront surgery, Upfront surgery - Pancreatic Cancer, Circulating Tumor Cell | Phase 3 | Recruiting | Elisabethinen Hospital | 100 | 2024-01-11 | 2024-04-30 |
| Liquid Biopsy for the Diagnosis of Intestinal-type Adenocarcinoma of the Ethmoid (BLADE) Liquid biopsy - Ethmoid Sinus Tumor, Adenocarcinoma | Not applicable | Unknown | University Hospital, Montpellier | 42 | 2023-12-01 | 2023-10-19 |
| Optimizing Endobronchial Ultrasound Sampling for Molecular Markers for NSCLC Endobronchial ultrasound - Lung Cancer, Non Small Cell Lung Cancer | Not applicable | Active not recruiting | Institut universitaire de cardiologie et de pneumologie de Québec, University Laval | 120 | 2023-05-01 | 2026-01-26 |
| ctDNA-guided Adjuvant Chemotherapy in Liver Metastasis of Colorectal Cancer Colorectal cancer resection combined with liver metastasis resection., FOLFOX chemotherapy regimen - Colorectal Cancer, Liver Metastases | Phase 3 | Recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 490 | 2023-02-20 | 2023-04-18 |
| Postoperation Maintenance Therapy for Resectable Liver Metastases of Colorectal Cancer Guided by ctDNA Colorectal resection surgery., FOLFOX chemotherapy regimen, Capecitabine - Colorectal Cancer, Liver Metastases | Phase 3 | Recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 346 | 2023-02-20 | 2023-04-04 |
| Analysis of Circulating DNA in Blood Samples of Glioma-affected Patients Liquid Biopsy - Glioma, Circulating Tumor Cell | Not applicable | Unknown | Corporacion Parc Tauli | 10 | 2023-01-31 | 2023-08-30 |
| CTCs in Breast Cancer After Neoadjuvant Treatment and Surgery: a Multicenter, Prospective Clinical Trial GILUPI CellCollector® - Breast Cancer, Circulating Tumor Cell | Not applicable | Recruiting | RenJi Hospital | 484 | 2022-09-14 | 2026-02-03 |
| Liquid Biopsy and Pancreas Cancer: Detection of AXL(+) CTCs (CTC-AXL-PANC) Detection of circulating tumor cells expressing Axl: CTC-AXL(+) - Pancreatic Ductal Adenocarcinoma, Metastatic Pancreatic Cancer | Not applicable | Recruiting | University Hospital, Montpellier | 63 | 2022-06-16 | 2026-06-22 |
| Impact of ctDNA in Cancer Early Detection and STAS Evaluation in Patients With GGOs cf DNA and ct DNA - Lung Cancer, Spreading of Tumor | Unknown | University of Roma La Sapienza | 80 | 2022-04-01 | 2022-11-08 | |
| Circulating Tumor DNA Based Decision for Adjuvant Treatment in Colon Cancer Stage II-III FOLFOXIRI, CAPOX - Colorectal Neoplasms Malignant, Minimal Residual Disease | Phase 2 | Active not recruiting | Fundación para la Investigación del Hospital Clínico de Valencia | 45 | 2022-01-01 | 2026-09-15 |
| Circulating Biomarkers in Patients With Anal Cancer Treated With Induction Chemotherapy Anal Cancer, Locally Advanced Squamous Cell Carcinoma | Unknown | Aarhus University Hospital | 60 | 2022-01-01 | 2022-02-10 | |
| Cetuxibab to Reduce Circulating Tumor Cells in Early Stage NSCLC Cetuximab - Lung Cancer, Surgery | Phase 2 | Withdrawn | The Netherlands Cancer Institute | 2022-01-01 | 2023-10-19 | |
| Prognostic Value of Liver Cancer CTCs Isolated by a Novel Microfluidic Platform Hepatocellular Carcinoma, Circulating Tumor Cell | Unknown | The Second Affiliated Hospital of Chongqing Medical University | 300 | 2021-12-01 | 2022-02-16 | |
| Circulating Tumor Cell Reducing No-touch Nephrectomy No-touch laparoscopic radical nephrectomy, Conventional laparoscopic radical nephrectomy, Laparoscopic total nephrectomy control arm - Renal Cell Carcinoma, Circulating Tumor Cell | Not applicable | Completed | Hospital de Santa Maria, Portugal | 44 | 2021-09-27 | 2022-11-14 |
| PD-L1 Expression on CTCs in HNSCC Patients Underwent Curative CCRT Head and Neck Squamous Cell Carcinoma, Circulating Tumor Cell | Unknown | Chang Gung Memorial Hospital | 50 | 2021-08-01 | 2021-08-18 | |
| Prospective Study for the Prognostic and Predictive Role of Circulating Tumor Cells in Patients With Oropharyngeal Squamous Cell Carcinoma: CTCO (Circulating Tumor Cells in the Oropharynx) CTC detection - Circulating Tumor Cell, Oropharyngeal Cancer | Completed | Hospices Civils de Lyon | 12 | 2021-06-23 | 2026-03-11 |
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Neoplastic Cells, Circulating (51) · Colorectal Neoplasms (9) · Lung Neoplasms (6) · Carcinoma, Hepatocellular (5) · Carcinoma, Non-Small-Cell Lung (4) · Squamous Cell Carcinoma of Head and Neck (4) · Breast Neoplasms (3) · Colonic Neoplasms (3) · Neoplasms (3) · Disease (2) · Gastrointestinal Neoplasms (2) · Pancreatic Neoplasms (2) · Prostatic Neoplasms (2) · Urinary Bladder Neoplasms (2) · Adenocarcinoma (1)
Neoplastic Processes (51) · Pathologic Processes (51) · Pathological Conditions, Signs and Symptoms (51) · Neoplasm Metastasis (50) · Neoplasms (48) · Neoplasms by Site (46) · Digestive System Diseases (24) · Digestive System Neoplasms (24) · Gastrointestinal Diseases (17) · Gastrointestinal Neoplasms (15) · Neoplasms by Histologic Type (15) · Intestinal Diseases (14) · Intestinal Neoplasms (14) · Neoplasms, Glandular and Epithelial (14) · Carcinoma (13)
Folfox protocol (2) · Liquid Biopsy (2) · Morphine (2) · Pirinitramide (2) · Adrenal Cortex Hormones (1) · Antiemetics (1) · Bevacizumab (1) · Blood Specimen Collection (1) · Capecitabine (1) · Cetuximab (1) · Cisplatin (1) · Conversion to Open Surgery (1) · Docetaxel (1) · Drug Therapy (1) · FOLFOXIRI protocol (1)
The Institute of Molecular and Translational Medicine, Czech Republic (4) · Fudan University (3) · RenJi Hospital (3) · Chang Gung Memorial Hospital (2) · Sixth Affiliated Hospital, Sun Yat-sen University (2) · The University of Hong Kong (2) · University Hospital, Montpellier (2) · AC Camargo Cancer Center (1) · Aarhus University Hospital (1) · Anhui Medical University (1) · Assistance Publique - Hôpitaux de Paris (1) · Centre Oscar Lambret (1) · Chinese University of Hong Kong (1) · Copenhagen University Hospital, Rigshospitalet (1) · Corporacion Parc Tauli (1)
China (14) · France (5) · Czechia (4) · Austria (2) · Canada (2) · Denmark (2) · Hong Kong (2) · Italy (2) · Netherlands (2) · Spain (2) · Taiwan (2) · Brazil (1) · Norway (1) · Portugal (1) · South Korea (1)
Marian Hajduch, MD PhD (2) · Andrew Z Wang, MD (1) · Chia-Hsun Hsieh, PhD (1) · Chong Zhao, M.D (1) · Egbert Smit, prof (1) · Fabrizio Romano (1) · Hu Liu, MD (1) · Jinsong Lu (1) · Ka On Lam, MBBS (1) · Karen L Wind, MD (1)
PMID 24618055, PMID 27468936, PMID 28632258, PMID 29168077, PMID 30472074, PMID 30602476, PMID 31042283, PMID 32017145, PMID 32289533, PMID 32487642, PMID 32637655, PMID 32702202, PMID 33479224, PMID 36855089, PMID 37643373, PMID 38242575