4 not yet recruiting, 4 recruiting, 3 completed, 1 active not recruiting. 6 Not applicable, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 2, Recruiting 2, Active not recruiting 1, Enrolling by invitation 1 |
| Phase 2 | 1 | Not yet recruiting 1 |
| Phase 3 | 1 | Not yet recruiting 1 |
Follow Chronic Venous Insufficiency, CVI: new trials by email Literature Review of Chronic Venous Insufficiency, CVI trials Research Report on Chronic Venous Insufficiency, CVI
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Structured Home-Based Exercise and Education for Chronic Venous Insufficiency Structured Home-Based Exercise and Education Program, Standard Care (in control arm) - Chronic Venous Insufficiency, CVI | Not applicable | Recruiting | Abant Izzet Baysal University | 120 | 2026-08-28 | 2026-08-31 |
| Pedal Pump Clinical Trial on Edema V2 Pedal Pump, Pedal Pump Sham - Lower Extremity Edema, Lower Extremity Edema Chronic | Not applicable | Recruiting | Hillcrest | 30 | 2026-08-21 | 2026-09-09 |
| The ReCAna for Lower ExtremIty Venous OBstructions and In-StEnt Restenosis Registry Recanalization and debulking - Chronic Venous Disease, Chronic Venous Insufficiency, CVI | Not yet recruiting | Intervene, Inc. | 500 | 2026-08-01 | 2026-08-03 | |
| Clinical Investigation of Safety and Effectiveness for the enVVe® System envve system - Chronic Venous Insufficiency, CVI | Phase 2 / Phase 3 | Not yet recruiting | Hancock Jaffe Laboratiores, Inc | 220 | 2026-07-01 | 2026-05-27 |
| The Use of Immersive Virtual Reality as a Method of Treating Anxiety and Procedural Pain During Endovenous Laser Ablation (EVLA) of Lower Varicose Veins Under Tumescent Anesthesia VR (VR-Control) - Chronic Venous Insufficiency, CVI | Not applicable | Enrolling by invitation | Bydgoszcz University of Science and Technology | 100 | 2026-06-10 | 2026-06-09 |
| Efficacy and Safety of Endovenous Ablation for Relief of Knee Pain in Elderly Patients With Lower Extremity Varicose Veins: A Prospective Observational Study Endovenous Ablation for Varicose Veins - Varicose Veins of Lower Limb, Chronic Venous Insufficiency, CVI | Not yet recruiting | Chengdu University of Traditional Chinese Medicine | 50 | 2025-12-10 | 2025-11-20 | |
| Risks and Benefits of Radiofrequency Ablation for Chronic Venous Insufficiency (CEAP C3-C6) in Patients Aged 80 and Over Endovenous Radiofrequency Ablation - Chronic Venous Insufficiency, CVI, Radiofrequency Ablation | Recruiting | Chengdu University of Traditional Chinese Medicine | 50 | 2025-10-01 | 2025-11-18 | |
| Knee Pain Relief After Endovenous Treatment for Lower Limb Varicose Veins: A Prospective Observational Study Endovenous Ablation for Varicose Veins - Varicose Veins of Lower Limb, Chronic Venous Insufficiency, CVI | Not yet recruiting | Chengdu University of Traditional Chinese Medicine | 50 | 2025-10-01 | 2025-09-09 | |
| Reducing Skin Tone Inequities in Chronic Venous Insufficiency Chronic Venous Insufficiency, CVI, Chronic Venous Insufficiency C2 or Higher | Recruiting | King's College London | 51 | 2025-06-01 | 2025-09-16 | |
| Safety of the Sonablate HIFU System for the Ablation of Incompetent Veins of the Periphery High Intensity focused ultrasound - Chronic Venous Insufficiency, CVI, Venous Malformations | Not applicable | Active not recruiting | Sonablate | 30 | 2024-09-11 | 2026-02-19 |
| Respiratory Functions, Aerobic Capacity and Quality of Life in Chronic Venous Insufficiency Chronic Venous Insufficiency, CVI | Completed | Izmir Democracy University | 38 | 2023-07-05 | 2025-01-21 | |
| Adding a Combined Program of Therapeutic Exercise and Self-massage to the Conventional Approach of Compression Stockings and Preventive Measures in Chronic Venous Insufficiency. Compression Stocking, Therapeutic exercise, Self-massage - Chronic Venous Insufficiency, CVI | Not applicable | Completed | University of Valencia | 34 | 2022-03-01 | 2024-12-11 |
| Clinical Study to Assess the Safety and Efficacy of Mechanochemical Ablation With Flebogrif in Patients With Great Saphenous Vein Insufficiency FLEBOGRIF - Chronic Venous Insufficiency, CVI | Not applicable | Completed | Balton Sp.zo.o. | 200 | 2019-08-08 | 2023-06-18 |
Blindness, Cortical (13) · Osteoarthritis, Knee (2) · Bites and Stings (1) · Blue rubber bleb nevus syndrome (1) · Congenital Lipomatous Overgrowth, Vascular Malformations, and Epidermal Nevi (1) · Embolism (1) · Embolism and Thrombosis (1) · Heart Failure (1) · Klippel-Trenaunay-Weber Syndrome (1) · Thrombosis (1) · Varicose Ulcer (1) · Venous Thrombosis (1)
Blindness (13) · Eye Diseases (13) · Nervous System Diseases (13) · Neurologic Manifestations (13) · Pathological Conditions, Signs and Symptoms (13) · Sensation Disorders (13) · Signs and Symptoms (13) · Vision Disorders (13) · Cardiovascular Diseases (4) · Vascular Diseases (3) · Arthritis (2) · Joint Diseases (2) · Musculoskeletal Diseases (2) · Osteoarthritis (2) · Rheumatic Diseases (2)
Radiofrequency Ablation (2) · Exercise Therapy (1) · Standard of Care (1) · Stockings, Compression (1)
Chengdu University of Traditional Chinese Medicine (3) · Abant Izzet Baysal University (1) · Balton Sp.zo.o. (1) · Bydgoszcz University of Science and Technology (1) · Hancock Jaffe Laboratiores, Inc (1) · Hillcrest (1) · Intervene, Inc. (1) · Izmir Democracy University (1) · King's College London (1) · Sonablate (1) · University of Valencia (1)
Poland (2) · Turkey (Türkiye) (2) · United States (2) · China (1) · Spain (1) · United Kingdom (1)
Kush R Desai, MD (1) · Naiem Nassiri, MD, FSVS, RPVI (1) · Sameh Sayfo, MD, MBA (1) · Victoria J Clemett, PhD, BNurs (1) · William A Marston, MD (1)
PMID 32318673, PMID 34239634, PMID 22422794, PMID 24072751, PMID 28631699, PMID 37070890, PMID 39162334, PMID 42532411