5 recruiting. 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Recruiting 5 |
Follow Chronic Cough: new trials by email Literature Review of Chronic Cough trials Research Report on Chronic Cough
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mechanisms of Change in Behavioral Cough Suppression Therapy for Refractory Chronic Cough BCS+inactive, BCS+active - Chronic Cough (CC), Refractory Chronic Cough | Phase 2 | Recruiting | University of Montana | 135 | 2026-08-13 | 2026-08-18 |
| A Study to Investigate the Efficacy and Safety of SC0032, a Magnesium Salt Oral Spray, in Adults With Refractory or Unexplained Chronic Cough SC0032, Placebo - Refractory Chronic Cough and Unexplained Chronic Cough | Phase 2 | Recruiting | Sensory Cloud, Inc. | 60 | 2026-07-13 | 2026-10-14 |
| The Effect of Nalbuphine Extended-Release (NAL ER) on Cough in Participants With Refractory Chronic Cough (RCC) NAL ER, Placebo - Refractory Chronic Cough | Phase 2 | Recruiting | Trevi Therapeutics | 100 | 2026-06-22 | 2026-10-13 |
| Efficacy of Two Doses of Duloxetine & Amitriptyline in Interstitial Lung Disease-related Cough Amitriptyline 25 MG, Amitriptyline 50 MG, Duloxetine 30 MG - Interstitial Lung Disease | Phase 2 | Recruiting | Mayo Clinic | 25 | 2021-11-01 | 2026-01-21 |
| Efficacy of Two Doses of Duloxetine and Amitriptyline in Subjects With Refractory Chronic Cough Duloxetine 30 MG, Duloxetine 60 MG, Amitriptyline 25 MG - Refractory Chronic Cough | Phase 2 | Recruiting | Mayo Clinic | 50 | 2021-11-01 | 2026-01-21 |
Cough (2) · Asthma (1) · Fibrosis (1) · Gastroesophageal Reflux (1) · Lung Diseases, Interstitial (1) · Pulmonary Fibrosis (1) · cough hypersensitivity syndrome (1) · upper airway cough syndrome (1)
Pathological Conditions, Signs and Symptoms (5) · Respiration Disorders (5) · Respiratory Tract Diseases (5) · Signs and Symptoms (5) · Signs and Symptoms, Respiratory (5) · Cough (3) · Lung Diseases (2) · Bronchial Diseases (1) · Deglutition Disorders (1) · Digestive System Diseases (1) · Esophageal Diseases (1) · Esophageal Motility Disorders (1) · Gastrointestinal Diseases (1) · Hypersensitivity (1) · Hypersensitivity, Immediate (1)
Amitriptyline (2) · Duloxetine Hydrochloride (2) · Nalbuphine (1)
Mayo Clinic (2) · Sensory Cloud, Inc. (1) · Trevi Therapeutics (1) · University of Montana (1)
United States (3) · Canada (1) · United Kingdom (1)
Vivek N Iyer, MD (2) · Amanda Gillespie, PhD (1) · Laurie J Slovarp, PhD (1)