3 not yet recruiting, 2 completed, 2 recruiting. 2 Not applicable, 2 Phase 2, 1 Early Phase 1, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Not yet recruiting 2 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 4 | 1 | Not yet recruiting 1 |
Follow cough hypersensitivity syndrome: new trials by email Literature Review of cough hypersensitivity syndrome trials Research Report on cough hypersensitivity syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A 2x2 Factorial, Randomized, Open-label Trial to Evaluate Neuromodulators and Cough Control Therapy in Patients With Refractory or Unexplained Chronic Cough Morphine Sulphate, Morphine Sulphate + Cough Control Therapy, Pregabalin - Cough, Refractory Chronic Cough | Phase 4 | Not yet recruiting | McMaster University | 124 | 2026-09-30 | 2026-10-19 |
| Effects of Energy Versus Mechanical Surgical Devices on Postoperative Cough Energy Device Vagus Nerve Transection, Mechanical Vagus Nerve Transection - Postoperative Cough, Cough Hypersensitivity Syndrome | Not applicable | Not yet recruiting | Tongji Hospital | 248 | 2026-09-01 | 2026-05-07 |
| Mechanisms of Change in Behavioral Cough Suppression Therapy for Refractory Chronic Cough BCS+inactive, BCS+active - Chronic Cough (CC), Refractory Chronic Cough | Phase 2 | Recruiting | University of Montana | 135 | 2026-08-13 | 2026-08-18 |
| Feasibility, Acceptability, and Safety Trial of Brief, Breath Control-Focused Acceptance and Commitment Therapy in Adults With Chronic Cough Acceptance and Commitment Therapy (ACT) - Chronic Cough | Not applicable | Not yet recruiting | University of North Carolina, Chapel Hill | 30 | 2026-08-01 | 2026-05-06 |
| The Safety, Feasibility, and Repeatability of Inhaled ATP Cough Challenges Adenosine 5'-triphosphate - Chronic Cough (CC), Asthma | Phase 1 | Recruiting | McMaster University | 33 | 2025-08-05 | 2025-08-29 |
| Influence on Cough and Airway Symptoms by Oral Capsaicin Capsicum Oleoresin, Placebos - Cough | Phase 2 | Completed | Vastra Gotaland Region | 55 | 2019-06-01 | 2026-09-01 |
| Cough Desensitization Therapy for Cough Hypersensitivity Syndrome Supra-threshold and progressive doses of diluted capsaicin via a Koko Digidoser nebulizer, Sub-threshold doses of diluted capsiacin via a KoKo Digidoser nebulizer - Cough | Early Phase 1 | Completed | University of Montana | 19 | 2019-05-01 | 2024-03-04 |
Chronic Cough (6) · Cough (4) · Asthma (1)
Pathological Conditions, Signs and Symptoms (7) · Respiration Disorders (7) · Respiratory Tract Diseases (7) · Signs and Symptoms (7) · Signs and Symptoms, Respiratory (7) · Cough (3) · Bronchial Diseases (1) · Hypersensitivity (1) · Hypersensitivity, Immediate (1) · Immune System Diseases (1) · Lung Diseases (1) · Lung Diseases, Obstructive (1) · Respiratory Hypersensitivity (1)
Acceptance and Commitment Therapy (1) · Adenosine Triphosphate (1) · Capsaicin (1) · Morphine (1) · Pregabalin (1) · oleoresins (1)
McMaster University (2) · University of Montana (2) · Tongji Hospital (1) · University of North Carolina, Chapel Hill (1) · Vastra Gotaland Region (1)
United States (3) · Canada (2) · China (1) · Sweden (1)
Laurie J Slovarp, PhD (2) · Amanda Gillespie, PhD (1) · Carolyn Novaleski, Ph.D., CCC-SLP (1) · Eva Millqvist, MD, PhD (1) · Imran Satia, MD PhD (1) · Peng Shu (1)
2016 (1), K23HL169934 (1)