4 completed, 2 recruiting, 1 active not recruiting, 1 unknown. 3 Phase 2, 2 Phase 1, 1 Early Phase 1, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Recruiting 2, Completed 1 |
| Phase 1 | 2 | Recruiting 1, Withdrawn 1 |
| Early Phase 1 | 1 | Active not recruiting 1 |
| Not applicable | 1 | Completed 1 |
Follow Carcinomatosis: new trials by email Literature Review of Carcinomatosis trials Research Report on Carcinomatosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dual Administration Of Intraperitoneal And Intravenous TROP2-Directed CAR-NK With TGF-Beta Receptor 2 (TGFBR2) Knock Out (KO) Therapy For Colorectal Cancer-Related Peritoneal Carcinomatosis: A Phase 1/2 Trial ("Chip-CRC Trial") Cyclophosphamide, Fludarabine, Cetuximab - Colorectal Cancer, Peritoneal Metastases | Phase 1 / Phase 2 | Recruiting | M.D. Anderson Cancer Center | 28 | 2026-04-20 | 2026-10-05 |
| Study of VG2025 Delivered Intraperitoneally in Patients With Advanced Solid Tumors With Carcinomatosis VG2025 - Advanced Solid Tumor, Carcinomatosis | Phase 1 | Withdrawn | M.D. Anderson Cancer Center | 2024-09-30 | 2025-02-17 | |
| A Phase II Study of Perioperative Paclitaxel in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive Cytology Paclitaxel, Dexamethasone, Diphenhydramine - Gastric Adenocarcinoma, Carcinomatosis | Phase 2 | Recruiting | M.D. Anderson Cancer Center | 30 | 2023-09-08 | 2026-05-22 |
| Psychological, Psychophysical and Epigenetic Determinants of Chronic Pain After Cytoreductive - Hyperthermic Intraoperative Chemotherapy Biospecimen Collection, Pain Assessment, Questionnaire Administration - Appendix Carcinoma, Carcinomatosis | Completed | M.D. Anderson Cancer Center | 24 | 2021-08-10 | 2024-02-13 | |
| Perioperative Coagulopathy in Patients Undergoing Cytoreductive Surgery and HIPEC Intraperitoneal Chemotherapy (HIPEC) ROTEM parameters, platelet function assay (PFA-100), von Willebrand and Factor XIII - Coagulation Disorder, Carcinomatosis | Completed | Hospitales Universitarios Virgen del Rocío | 46 | 2020-03-27 | 2021-03-09 | |
| Adavosertib Before Surgery in Treating Patients With Advanced High Grade Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Adavosertib, Laboratory Biomarker Analysis - Advanced Fallopian Tube Carcinoma, Advanced Ovarian Carcinoma | Early Phase 1 | Active not recruiting | M.D. Anderson Cancer Center | 38 | 2016-02-04 | 2026-10-06 |
| Immunologic Profile of Peritoneal Cancer HIPEC - Carcinomatosis | Unknown | MercyOne Des Moines Medical Center | 60 | 2016-01-01 | 2020-09-23 | |
| B-type Natriuretic Peptide in the Diagnosis of Heart Failure Related Ascites BNP, SAAG, ascites total protein, echocardiography - Heart Failure, Liver Cirrhosis | Not applicable | Completed | University of Sao Paulo | 278 | 2010-06-01 | 2012-12-20 |
| Octreotide Compared to Placebo in Patients With Inoperable Bowel Obstruction Due to Peritoneal Carcinomatosis Octreotide LAR, Octreotide (Immediate release), methylprednisolone - Peritoneal Neoplasms, Intestinal Obstruction | Phase 2 | Completed | Novartis Pharmaceuticals | 64 | 2005-09-01 | 2011-09-23 |
Carcinoma (9) · Colorectal Neoplasms (2) · Appendiceal Neoplasms (1) · Ascites (1) · Colorectal Cancer, Hereditary Nonpolyposis, Type 6 (1) · Fallopian Tube Neoplasms (1) · Heart Failure (1) · Hemostatic Disorders (1) · Intestinal Obstruction (1) · Liver Cirrhosis (1) · Peritoneal Neoplasms (1) · Stomach Neoplasms (1)
Neoplasms (9) · Neoplasms by Histologic Type (9) · Neoplasms, Glandular and Epithelial (9) · Digestive System Diseases (4) · Neoplasms by Site (4) · Digestive System Neoplasms (3) · Gastrointestinal Diseases (3) · Intestinal Diseases (3) · Cardiovascular Diseases (2) · Colonic Diseases (2) · Gastrointestinal Neoplasms (2) · Intestinal Neoplasms (2) · Rectal Diseases (2) · Abdominal Neoplasms (1) · Adnexal Diseases (1)
Calcium Dobesilate (1) · Cetuximab (1) · Cyclophosphamide (1) · Dexamethasone (1) · Diphenhydramine (1) · Famotidine (1) · Hyperthermic Intraperitoneal Chemotherapy (1) · Methylprednisolone (1) · Octreotide (1) · Paclitaxel (1) · adavosertib (1) · fludarabine (1) · fludarabine phosphate (1)
M.D. Anderson Cancer Center (5) · Hospitales Universitarios Virgen del Rocío (1) · MercyOne Des Moines Medical Center (1) · Novartis Pharmaceuticals (1) · University of Sao Paulo (1)
United States (6) · Brazil (1) · France (1) · Spain (1)
Alberto Q. Farias, MD, PhD (1) · Brian Badgwell, MD (1) · Jan Franko, MD, PhD (1) · Juan P Cata (1) · Paula M Smith, MD (1) · Shannon N Westin (1) · Siqing Fu, MD,PHD (1)