7 completed, 5 recruiting, 3 not yet recruiting, 1 terminated. 7 Phase 1, 5 Not applicable, 4 Phase 2, 2 Early Phase 1.
Follow Cannabis Intoxication: new trials by email Literature Review of Cannabis Intoxication trials Research Report on Cannabis Intoxication
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Cannabidiol (CBD) on a Fixed Dose of Delta-9-tetrahydrocannabinol (THC) 0mg THC + 0mg CBD Brownie, 10mg THC + 0mg CBD Brownie, 10mg THC + 10mg CBD Brownie - Cannabis Intoxication | Phase 1 | Not yet recruiting | Johns Hopkins University | 70 | 2027-02-01 | 2026-10-15 |
| Effects of Various Cannabis Strains on Perceptual, Subjective and Objective Use Outcomes Cannabis, 0 mg THC (placebo) - Cannabis Intoxication | Phase 1 | Recruiting | Johns Hopkins University | 70 | 2026-09-15 | 2026-09-18 |
| Neuroimaging of Adolescent Cannabis Use Treatment Contingency Management, Elastic Net Regression - Cannabis Use, Cannabis Dependence | Not applicable | Recruiting | Indiana University | 80 | 2026-06-15 | 2026-06-22 |
| Pregnenolone as a Treatment for Cannabis Intoxication Cannabis, Pregnenolone 250 mg, Pregnenolone 500 mg - Cannabis Intoxication | Phase 2 | Recruiting | Johns Hopkins University | 20 | 2026-04-24 | 2026-09-29 |
| Exploring The Effect Of Cannabidiol On Cannabis Tolerance Using A Novel Vaporiser Device In Heavy Users (Stage 1) delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) - Cannabis Intoxication | Not applicable | Not yet recruiting | King's College London | 10 | 2026-03-01 | 2026-03-13 |
| THC + CBD and Memory Study High THC/No CBD Marihuana, High THC/High CBD Marihuana, No THC/No CBD Marihuana - Marijuana Use, Cannabis Use | Early Phase 1 | Not yet recruiting | Hartford Hospital | 9 | 2025-12-01 | 2025-03-17 |
| Study of an Oral Fluid Testing Approach Biologic testing for THC - Cannabis Use, Cannabis Intoxication | Recruiting | Boston Children's Hospital | 200 | 2025-10-27 | 2026-10-22 | |
| The Efficacy of a Smart Phone-based Test on Measuring Pupillary Light Reflex Alterations Following Cannabis Use Healthy in Adults Tetrahydrocannabinol (10 mg), Tetrahydrocannabinol (25 mg), Pupillary Light Reflex (PLR) Test - Cannabis Intoxication, Drug Effects | Not applicable | Completed | Sobereye Inc. | 20 | 2025-05-27 | 2026-10-06 |
| Vaporized Cannabis Administration and Co-Administration of Alcohol on Impairment Cannabis, Alcohol, Placebo Cannabis - Cannabis Intoxication, Alcohol Intoxication | Phase 1 | Recruiting | Johns Hopkins University | 90 | 2024-09-26 | 2026-09-08 |
| Cannabis Impairment Detection Device Study Cannabis Impairment Test - Cannabis Intoxication | Not applicable | Completed | Gaize | 362 | 2022-09-08 | 2025-08-17 |
| Effects of Cannabis/Alcohol on Driving Performance and Field Sobriety Tests Cannabis, Alcohol - Driving Impaired, Alcohol Intoxication | Phase 1 / Phase 2 | Withdrawn | University of California, San Diego | 2022-08-01 | 2023-09-07 | |
| The Impact of Oral Cannabis Administration and Co-Administration of Alcohol on Impairment Cannabis, Alcohol - Cannabis Intoxication, Alcohol Intoxication | Phase 1 | Completed | Johns Hopkins University | 70 | 2022-02-17 | 2026-08-03 |
| Eye Movement Tracking to Detect Impairment Due to Acute Cannabis Intoxication EyeBOX - Impairment, Cannabis Intoxication | Completed | Oculogica, Inc. | 225 | 2021-02-01 | 2021-09-13 | |
| Evaluation of an Eye Tracking Sensor to Detect Cannabis Impairment Virtual Reality Eye Tracking after smoking Cannabis - HTC Vive Pro-Eye, Cannabis cigarette - 4.0% THC - Cannabis Intoxication | Early Phase 1 | Terminated | Battelle Memorial Institute | 3 | 2020-02-03 | 2021-10-01 |
| Detection of Cannabis Impairment With an Eye Tracker Cannabis Sativa - Cannabis Intoxication | Phase 1 / Phase 2 | Completed | Centre for Addiction and Mental Health | 10 | 2019-08-15 | 2019-12-12 |
| Do Adolescents and Adults Differ in Their Acute Response to Cannabis? Cannabis with delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), Cannabis with THC without CBD, Placebo cannabis - Cannabis, Cannabis Intoxication | Not applicable | Completed | University College, London | 48 | 2019-03-11 | 2021-09-29 |
| The Impact and Detection of Driving Impairments Associated With Acute Cannabis Smoking Cannabis - Cannabis Intoxication | Phase 1 / Phase 2 | Completed | University of California, San Diego | 199 | 2017-02-24 | 2022-01-04 |
Marijuana Abuse (11) · Alcoholic Intoxication (3) · Driving Under the Influence (2) · Marijuana Use (2) · Behavior, Addictive (1) · Marijuana Smoking (1) · Memory Disorders (1) · Substance-Related Disorders (1)
Chemically-Induced Disorders (13) · Mental Disorders (13) · Substance-Related Disorders (12) · Behavior (4) · Alcohol-Related Disorders (3) · Criminal Behavior (2) · Dangerous Behavior (2) · Compulsive Behavior (1) · Impulsive Behavior (1) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1) · Neurologic Manifestations (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1) · Smoking (1)
Dronabinol (9) · nabiximols (9) · Ethanol (3) · Cannabidiol (2) · Pregnenolone (1)
Johns Hopkins University (5) · University of California, San Diego (2) · Battelle Memorial Institute (1) · Boston Children's Hospital (1) · Centre for Addiction and Mental Health (1) · Gaize (1) · Hartford Hospital (1) · Indiana University (1) · King's College London (1) · Oculogica, Inc. (1) · Sobereye Inc. (1) · University College, London (1)
United States (10) · Canada (3) · United Kingdom (2)
Carlos A Zamarripa, PhD (2) · Tory Spindle, PhD (2) · Alecia Dager, PhD (1) · Bernard Le Foll, MD PhD (1) · David Crowley, MD (1) · David Wolinsky, MD (1) · Godfrey Pearlson, MD (1) · Ken Fichtler (1) · Lydia A. Shrier, MD, MPH (1) · Michael Stevens, PhD (1) · Rosina Samadani, Ph.D. (1) · Thomas D Marcotte, PhD (1)
PMID 31527291, PMID 34173005, PMID 15094417, PMID 17063973, PMID 17916224, PMID 21049267, PMID 26144593, PMID 26257143, PMID 30615854, PMID 34185831, PMID 34432541, PMID 35032682, PMID 35080588, PMID 36642667, PMID 36750134, PMID 37531115, PMID 38416223, PMID 42065887
R01DA052295 (2), K23DA063832 (1), R01DA059584 (1), R01DA064583 (1), R21DA063854 (1)