12 completed, 4 unknown, 1 active not recruiting. 6 Phase 2, 4 Phase 3, 4 Phase 4, 2 Phase 1, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 4, Unknown 2 |
| Phase 3 | 4 | Completed 3, Active not recruiting 1 |
| Phase 4 | 4 | Completed 2, Unknown 2 |
| Phase 1 | 2 | Completed 2 |
| Not applicable | 1 | Completed 1 |
Follow Miconazole: new trials by email Literature Review of Miconazole trials Research Report on Miconazole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Efficacy of Intralesional 0.5% Triamcinolone Acetonide in 0.2% Fluconazole Solution vs 0.1% Topical Mometasone Furoate With 2% Miconazole Nitrate Cream in the Treatment of Chronic Paronychia: An Intraindividual Randomized Controlled Trial. Intralesional triamcinolone acetonide and fluconazole, Topical mometasone furoate and miconazole nitrate, Elica-M® - Chronic Paronychia | Phase 3 | Active not recruiting | Cairo University | 21 | 2024-08-17 | 2025-12-31 |
| Phase III Efficacy and Safety Study of Miconazole Oil for Otomycosis Miconazole (2%) oil and mineral oil, Placebo - Otomycosis | Phase 3 | Completed | Hill Dermaceuticals, Inc. | 112 | 2023-03-02 | 2026-05-12 |
| Study Evaluating the Efficacy and Safety of Miconazole Nitrate + Domiphen Bromide Vaginal Cream in the Treatment of Subjects With Acute Vulvovaginal Candidiasis Miconazole Nitrate 2% + Domiphen Bromide Low Dose, Miconazole Nitrate 2% + Domiphen Bromide High Dose, Miconazole Nitrate 2% - Acute Vulvovaginal Candidiasis | Phase 2 | Unknown | Aesculape CRO Belgium BV | 90 | 2021-09-13 | 2022-03-14 |
| Use of Maqui Berry Extract in Treating Oral Candidiasis in Diabetes Mellitus Patients and Systemically Healthy Persons Miconazole, CandBerrol® lozenges - Oral Candidiases | Phase 4 | Unknown | University of Belgrade | 90 | 2021-05-01 | 2023-06-23 |
| Efficacy and Safety Study of Miconazole Oil Versus Vehicle on Fungal Infection of the Ear Canal (Otomycosis) miconazole 2% oil, vehicle oil - Otomycosis | Phase 2 / Phase 3 | Completed | Hill Dermaceuticals, Inc. | 382 | 2020-07-08 | 2024-01-19 |
| Systemic Uptake of Diclofenac Sodium in Combination With Miconazole as Antifungal Nail Gel When Applied Daily With Monitoring of Hepatic and Renal Enzymes, and Serum Levels of Diclofenac 12 Hours After Application, and at 3 and 6 Months Study Antifungal Nail Gel Study - Tinea Unguium, Onychomycosis | Phase 2 | Unknown | William N Handelman | 30 | 2020-05-01 | 2020-04-10 |
| Dose-Ranging Study for Miconazole Oil for Treatment of Otomycosis 7-Day Miconazole Oil (Miconazole 2%), 14-Day Miconazole Oil (Miconazole 2%), 14-Day Placebo - Oil Vehicle - Otomycosis | Phase 2 | Completed | Hill Dermaceuticals, Inc. | 65 | 2017-04-20 | 2022-10-05 |
| Efficacy of Standardized-propolis Extract (EPP-AF®) Gel Formulation as Buccal Antiseptic Propolis, Miconazole - Candidiasis, Oral, Stomatitis, Denture | Phase 3 | Completed | University of Sao Paulo | 40 | 2016-01-01 | 2016-06-30 |
| Clinical Trial Comparing Dapaconazole Versus Miconazole in Patients With Tinea Cruris Dapaconazole, Miconazole Nitrate - Tinea Cruris | Phase 2 | Completed | Galeno Desenvolvimento de Pesquisas Clínicas | 51 | 2014-01-29 | 2017-12-02 |
| DDI Potential: Dapivirine Vaginal Ring and Miconazole Nitrate dapivirine, miconazole - HIV | Phase 1 | Completed | International Partnership for Microbicides, Inc. | 36 | 2012-12-01 | 2017-09-08 |
| Clinical Trial of Hydroquinone Versus Miconazol in Melasma Miconazole, Hydroquinone - Melasma | Phase 4 | Unknown | Universidad Autonoma de San Luis Potosí | 60 | 2011-10-01 | 2014-12-02 |
| Topical Metronidazole and Miconazole Co-formulated Vaginal Suppositories for Preventing Vaginal Infections in HIV-seronegative Women Neo-Penotran® Forte (active ingredient Metronidazole & Miconazole Nitrate), Placebo - Bacterial Vaginosis, Candidiasis | Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 234 | 2011-04-01 | 2014-10-06 |
| Observational Program Neo-Penotran® Forte Metronidazole/Miconazole (Neo-Penotran Forte, BAY86-5276) - Vaginal Candidiasis, Bacterial Vaginosis | Completed | Bayer | 13024 | 2010-10-01 | 2016-07-25 | |
| An Efficacy and Safety Study of Miconazole and Hydrocortisone Cream in the Treatment of Vulvar Candidiasis Miconazole plus Hydrocortisone - Vulva; Candidiasis | Phase 4 | Completed | Janssen Pharmaceutica | 115 | 2009-01-01 | 2013-03-25 |
| Uptake of the Antifungal Miconazole and Effect on Estrogen Metabolizing Enzymes in Humans Brentan (miconazole) - Healthy | Not applicable | Completed | University of Southern Denmark | 20 | 2008-04-01 | 2008-10-17 |
| Effect of Exercise on Spread of the Miconozole Nitrate OVULE in the Vagina Miconazole nitrate, Magnetic resonance imaging, Moderate levels of exercise - Health, Vulvovaginal Candidiasis | Phase 4 | Completed | University of Pennsylvania | 12 | 2004-07-01 | 2011-08-09 |
| Effects of Miconazole on Blood Flow Miconazole, L-NMMA, Bradykinin - Healthy | Phase 1 | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 15 | 2000-02-01 | 2008-03-04 |
Candidiasis, Vulvovaginal (3) · Otomycosis (3) · Candidiasis (2) · Candidiasis, Oral (2) · Vaginosis, Bacterial (2) · Aneurysm (1) · Melanosis (1) · Onychomycosis (1) · Stomatitis, Denture (1) · Tinea (1) · Tinea Cruris (1) · Trichomonas Infections (1) · Trichomonas Vaginitis (1)
Hill Dermaceuticals, Inc. (3) · Aesculape CRO Belgium BV (1) · Bayer (1) · Cairo University (1) · Galeno Desenvolvimento de Pesquisas Clínicas (1) · International Partnership for Microbicides, Inc. (1) · Janssen Pharmaceutica (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Universidad Autonoma de San Luis Potosí (1) · University of Belgrade (1) · University of Pennsylvania (1) · University of Sao Paulo (1) · University of Southern Denmark (1) · William N Handelman (1)
United States (7) · Belgium (2) · Brazil (2) · Denmark (1) · Egypt (1) · Kazakhstan (1) · Kenya (1) · Mexico (1) · Serbia (1)
Kenneth Hodge, MD (2) · Quyen T Nguyen, MD (2) · Amalia Reyes-Herrera, M.D. (1) · Arnaldo Rivera, MD (1) · Bertha Torres-Alvarez, M.D. (1) · Brent Benscoter, MD (1) · Erica N Lia, PhD (1) · Gary Brandt, MD (1) · Gisela M Pina, DDS (1) · Habiba K Edrees, Dermatology Resident (1) · Jack Wazen, MD (1) · Jean-Paul Deslypere, MD (1) · Jeffrey Adelglass, MD (1)