9 completed, 9 recruiting, 5 unknown, 3 active not recruiting. 10 Not applicable, 5 Phase 1, 5 Phase 2, 3 Phase 3.
Follow Cancer Metastatic: new trials by email Literature Review of Cancer Metastatic trials Research Report on Cancer Metastatic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Trastuzumab Deruxtecan + Stereotactic Radiosurgery (SRS) in HER2+ Breast Cancer Brain Metastases Trastuzumab Deruxtecan, Stereotactic Radiosurgery - Breast Cancer, HER2-positive Breast Cancer | Phase 1 | Not yet recruiting | Baptist Health South Florida | 20 | 2027-01-01 | 2026-10-01 |
| Safety, Tolerability, and Preliminary Antitumor Activity of Cationic Peptide-IL22BP mRNA in Advanced Solid Tumors CP-IL22BP mRNA intratumorally injection - mRNA Vaccine, Solid Tumor Cancer | Phase 1 | Recruiting | West China Hospital | 18 | 2026-07-13 | 2026-07-14 |
| Symptom Management and Survivorship Plus Coaching for Advanced Cancer Survivors and Their Caregivers Symptom Management and Survivorship Handbook + Coaching, Symptom Management and Survivorship Handbook - Cancer Metastatic, Symptoms and Signs | Not applicable | Recruiting | University of Arizona | 200 | 2026-05-06 | 2026-07-20 |
| Stereotactic Body Radiotherapy vs Conventional Palliative Radiotherapy for Painful Non-Spine Bone Metastases Standard Conventional Radiotherapy, Stereotactic Body Radiotherapy - Cancer Metastatic | Phase 3 | Recruiting | Canadian Cancer Trials Group | 230 | 2025-03-07 | 2026-10-16 |
| Telerehabilitation in Oncology Patients Therapeutic Exercise and Education - Cancer Metastatic, Cancer | Not applicable | Completed | University of Malaga | 30 | 2023-10-01 | 2026-04-08 |
| Effects of Dexmedetomidine/Lidocaine/Intrathecal Morphine on Cancer Metastasis Biomarker After Colorectal Surgery Lidocaine IV, Dexmedetomidine IV, intrathecal morphine - Colorectal Cancer, Anesthesia | Not applicable | Completed | Samsung Medical Center | 114 | 2023-04-12 | 2025-04-02 |
| Evaluation of an Automated System to Culture Metastatic Patient Circulating Tumor Cells in Embryonated Chicken Eggs (in Ovo Culture) Patient sampling. - Cancer Metastatic, Prostate Cancer | Not applicable | Completed | Hospices Civils de Lyon | 101 | 2023-02-14 | 2025-11-20 |
| The Italian Registry of Malnutrition in Oncology Cohort observational - Cancer, Cancer Metastatic | Recruiting | Fondazione IRCCS Policlinico San Matteo di Pavia | 1500 | 2022-10-25 | 2024-04-03 | |
| Web-based Support for Family Caregivers of Patients With Advanced Cancer Narstaende.se - Family, End of Life | Not applicable | Active not recruiting | Ersta Sköndal University College | 204 | 2022-09-01 | 2025-08-08 |
| The BurnAlong Pilot Study for Adolescent and Young Adult Cancer Survivors Virtual group based physical activity (BurnAlong) and Social Media Discussion Board - Cancer, Cancer Metastatic | Not applicable | Completed | Cedars-Sinai Medical Center | 8 | 2022-07-25 | 2025-02-26 |
| Determine Safety & Recommended Phase 2 Dosing of Zeaxanthin Alone or in Combination w/Pembrolizumab in Patients With Metastatic Cancer Zeaxanthin, Zeaxanthin Plus Pembrolizumab - Cancer Metastatic, Metastatic Solid Tumor | Phase 1 | Recruiting | Valley Health System | 72 | 2022-04-17 | 2026-06-05 |
| Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1) nab-sirolimus - Tumor, Tumor, Solid | Phase 2 | Completed | Aadi Bioscience, Inc. | 128 | 2022-03-10 | 2026-09-28 |
| Intratumoral CAN1012(Selective TLR7 Agonist) in Subjects With Solid Tumors CAN1012 - Solid Tumor, Cancer Metastatic | Phase 1 | Unknown | CanWell Pharma Inc. | 36 | 2022-01-20 | 2023-12-22 |
| UNC Childhood, Adolescent, and Young Adult Cancer Cohort Pediatric Cancer, Cancer | Recruiting | UNC Lineberger Comprehensive Cancer Center | 500 | 2021-12-17 | 2026-05-12 | |
| IlluminOss Photodynamic Bone Stabilization System for the Treatment of Impending and Actual Pelvis Fractures IlluminOss pelvic implant for oncologic indication, IlluminOss pelvic implant for geriatric trauma indication - Cancer Metastatic, Trauma | Recruiting | Massachusetts General Hospital | 100 | 2021-11-18 | 2026-01-16 | |
| Real Word European Registry of NTRK Fusions and Other Rare Actionable Fusions (TRacKING) Data collection and quality of life questionnaire - Cancer, Cancer Metastatic | Unknown | Centre Leon Berard | 500 | 2021-06-22 | 2021-08-02 | |
| Study of AK112 in the Treatment of Advanced Gynecological Tumors AK112 - Gynecologic Cancer, Cancer Metastatic | Phase 2 | Completed | Akeso | 53 | 2021-04-09 | 2025-02-28 |
| Improving Public Cancer Care by Implementing Precision Medicine in Norway Atezolizumab - Cancer Metastatic | Phase 2 | Recruiting | Oslo University Hospital | 3000 | 2021-04-01 | 2024-02-29 |
| Low-Level Laser Effects on Orthodontic Tooth Movement of Periodontally Compromised Patients. Biolase ;Low Level Laser - Periodontal Diseases, Cancer Metastatic | Not applicable | Unknown | Faculty of Dental Medicine for Girls | 20 | 2021-04-01 | 2023-02-24 |
| Lay Coach-Led Early Palliative Care for Underserved Advanced Cancer Caregivers: The Project ENABLE Cornerstone RCT ENABLE Cornerstone - Cancer Metastatic, Family Members | Phase 3 | Active not recruiting | University of Alabama at Birmingham | 387 | 2021-01-07 | 2026-07-28 |
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Neoplasm Metastasis (28) · Neoplasms (13) · Breast Neoplasms (5) · Colorectal Neoplasms (4) · Lung Neoplasms (3) · Prostatic Neoplasms (3) · Brain Neoplasms (2) · Death (2) · Glioblastoma (2) · Head and Neck Neoplasms (2) · Leukemia (2) · Lymphoma (2) · Multiple Myeloma (2) · Ovarian Neoplasms (2) · Pancreatic Neoplasms (2)
Neoplastic Processes (28) · Pathologic Processes (28) · Pathological Conditions, Signs and Symptoms (28) · Neoplasms (15) · Neoplasms by Site (8) · Breast Diseases (5) · Digestive System Diseases (5) · Digestive System Neoplasms (5) · Gastrointestinal Diseases (5) · Skin Diseases (5) · Skin and Connective Tissue Diseases (5) · Colonic Diseases (4) · Endocrine Gland Neoplasms (4) · Endocrine System Diseases (4) · Gastrointestinal Neoplasms (4)
Radiosurgery (2) · abemaciclib (2) · pembrolizumab (2) · Anastrozole (1) · Bevacizumab (1) · Capecitabine (1) · Data Collection (1) · Dexmedetomidine (1) · Educational Status (1) · Exercise Therapy (1) · HhAntag691 (1) · LY3214996 (1) · Letrozole (1) · Lidocaine (1) · Morphine (1)
Aadi Bioscience, Inc. (1) · Akeso (1) · Anita Turk (1) · Assistance Publique - Hôpitaux de Paris (1) · Baptist Health South Florida (1) · CanWell Pharma Inc. (1) · Canadian Cancer Trials Group (1) · Care Partners (1) · Cedars-Sinai Medical Center (1) · Centre Leon Berard (1) · Ersta Sköndal University College (1) · Faculty of Dental Medicine for Girls (1) · Fondazione IRCCS Policlinico San Matteo di Pavia (1) · Gillian Gresham (1) · Hospices Civils de Lyon (1)
United States (14) · France (4) · China (2) · Italy (2) · South Korea (2) · Spain (2) · United Kingdom (2) · Austria (1) · Canada (1) · Czechia (1) · Denmark (1) · Egypt (1) · Germany (1) · Netherlands (1) · Norway (1)
Andrew Smitherman, MD (1) · Anita Turk, MD (1) · Arjun Sahgal (1) · Beihua Kong, MD (1) · Celina H Shirazipour, Ph.D. (1) · Gillian Gresham, PhD (1) · Manmeet Ahluwalia (1) · Mihye Park, MD, PhD (1) · Mohsena A Abdelrazek, Lecturer (1) · Philip Friedlander, MD (1) · Qi Zhou, MD (1) · Susan M Perkins, PhD (1) · Susan Whiteway, LtCol USAF, MD (1)
PMID 30229370, PMID 35568909, PMID 35655285, PMID 36997247, PMID 40219770, PMID 42228944, PMID 42334850, PMID 42624933, PMID 42786668
2018 (1), 2019 (1), R01CA235632 (1), R37CA252868 (1)