3 completed, 1 active not recruiting, 1 recruiting. 5 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 3, Active not recruiting 1, Recruiting 1 |
| Phase 1 | 1 | Active not recruiting 1 |
Follow Brainstem Glioma: new trials by email Literature Review of Brainstem Glioma trials Research Report on Brainstem Glioma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG). BCB-276 - Diffuse Intrinsic Pontine Glioma, DIPG | Phase 2 | Recruiting | BrainChild Bio, Inc | 75 | 2026-09-04 | 2026-10-28 |
| A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas Mebendazole, Vincristine, Carboplatin - Pilomyxoid Astrocytoma, Pilocytic Astrocytoma | Phase 1 / Phase 2 | Active not recruiting | Julie Krystal | 10 | 2013-10-22 | 2026-08-06 |
| Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma Valproic acid, Bevacizumab, Radiation therapy - Glial Cell Tumors, Malignant Gliomas | Phase 2 | Completed | Baylor College of Medicine | 38 | 2009-09-01 | 2021-07-21 |
| A Study of Capecitabine (Xeloda®) and Concomitant Radiation Therapy in Children With Newly Diagnosed Brainstem Gliomas Capecitabine, Radiation therapy - Brainstem Glioma | Phase 2 | Completed | Hoffmann-La Roche | 45 | 2007-05-01 | 2014-02-06 |
| ANGIOCOMB Antiangiogenic Therapy for Pediatric Patients With Diffuse Brain Stem and Thalamic Tumors Thalidomide, etoposide, celecoxib - Brainstem Glioma | Phase 2 | Completed | Helsinki University Central Hospital | 50 | 2005-01-01 | 2014-05-08 |
Diffuse Intrinsic Pontine Glioma (3) · Astrocytoma (2) · Brain Neoplasms (2) · Glioblastoma (2) · Glioma (2) · Gliosarcoma (2) · Central Nervous System Neoplasms (1) · Neoplasms (1) · Neoplasms, Neuroepithelial (1) · Optic Nerve Glioma (1)
Brain Diseases (3) · Brain Stem Neoplasms (3) · Central Nervous System Diseases (3) · Infratentorial Neoplasms (3) · Neoplasms by Histologic Type (3) · Neoplasms by Site (3) · Neoplasms, Germ Cell and Embryonal (3) · Neoplasms, Glandular and Epithelial (3) · Neoplasms, Nerve Tissue (3) · Nervous System Diseases (3) · Nervous System Neoplasms (3) · Neuroectodermal Tumors (3) · Central Nervous System Neoplasms (2) · Neoplasms (2) · Neoplasms, Neuroepithelial (2)
Bevacizumab (2) · Radiotherapy (2) · Capecitabine (1) · Carboplatin (1) · Celecoxib (1) · Etoposide (1) · Irinotecan (1) · Mebendazole (1) · Temozolomide (1) · Thalidomide (1) · Valproic Acid (1) · Vincristine (1)
Baylor College of Medicine (1) · BrainChild Bio, Inc (1) · Helsinki University Central Hospital (1) · Hoffmann-La Roche (1) · Julie Krystal (1)
United States (4) · Finland (1)
Cori Abikoff, MD (1) · Jack Su, MD (1) · Julie Krystal, MD (1) · Sanna-Maria Kivivuori, md (1)