5 not yet recruiting, 2 recruiting, 1 active not recruiting, 1 completed. 6 Phase 2, 3 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Not yet recruiting 4, Active not recruiting 1, Completed 1 |
| Phase 1 | 3 | Recruiting 2, Not yet recruiting 1 |
| Phase 3 | 1 | Not yet recruiting 1 |
Follow Brain Metastases From Solid Tumors: new trials by email Literature Review of Brain Metastases From Solid Tumors trials Research Report on Brain Metastases From Solid Tumors
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 1/2 Study Evaluating the Safety, PK/PD, and Clinical Activity of Oral JBI-778 in Patients With Brain Metastases, Leptomeningeal Disease, or Recurrent High Grade Glioma JBI-778 - Brain Metastases From Solid Tumors, Leptomeningeal Disease | Phase 1 / Phase 2 | Not yet recruiting | Jubilant Therapeutics Inc. | 113 | 2028-04-01 | 2026-08-07 |
| The METAMAX Study: MT027 Allogeneic CAR-T for Brain Metastases From Advanced Solid Tumors Intracerebroventricular injection of MT027 UCAR-T Cell targeting B7H3 - Brain Metastases From Solid Tumors | Phase 2 | Not yet recruiting | T-MAXIMUM Pharmaceutical Inc | 40 | 2027-12-30 | 2026-10-27 |
| Evaluating Biomarkers of Cognitive Dysfunction in Patients With Cancer Blood sample, Brain magnetic resonance imaging (MRI), Brain Health Assessment - Brain Tumor Adult, Brain Metastases From Solid Tumors | Not yet recruiting | University of California, San Francisco | 40 | 2026-12-15 | 2026-10-29 | |
| Comparison of the Therapeutic Effects of Methylprednisolone and Dexamethasone on Peritumoral Edema During Radiotherapy for Brain Metastases: Methylprednisolone (Corticosteroid), Dexamethasone - Brain Metastases From Solid Tumors | Phase 2 / Phase 3 | Not yet recruiting | The Second Affiliated Hospital of Hainan Medical University | 400 | 2026-04-15 | 2026-04-21 |
| SMART Trial: Cognitive Sparing Brain Radiotherapy for Multiple Brain Metastases SRS, CS-WBRT, HA-WBRT - Brain Metastases From Solid Tumors | Phase 2 | Not yet recruiting | National Taiwan University Hospital | 90 | 2026-04-01 | 2026-04-13 |
| Phase 2b Imaging Study of RAD101 in Participants With Suspected Recurrent Brain Metastases RAD101 (18F-FPIA) - Brain Metastases From Solid Tumors | Phase 2 | Active not recruiting | Radiopharm Theranostics, Ltd | 30 | 2024-12-13 | 2026-08-12 |
| A Phase 1/1b Study of IAM1363 in HER2 Cancers IAM1363 - HER2 Mutation-Related Tumors, HER2 | Phase 1 | Recruiting | Iambic Therapeutics, Inc | 383 | 2024-03-25 | 2026-09-09 |
| A First-In-Human, Phase 1 Study Evaluating Oral TACC3 PPI Inhibitor, AO-252, in Advanced Solid Tumors With or Without Brain Metastases AO-252 - Solid Tumor Malignancies, Brain Metastases From Solid Tumors | Phase 1 | Recruiting | A2A Pharmaceuticals Inc. | 86 | 2023-11-02 | 2026-08-17 |
| 131I-L19SIP Radioimmunotherapy (RIT) in Combination With External Beam Radiation in Patients With Multiple Brain Metastases From Solid Tumors 131I-L19SIP Radioimmunotherapy (RIT) in Combination With Whole Brain Radiation Therapy (WBRT) - Brain Metastases From Solid Tumors | Phase 2 | Completed | Philogen S.p.A. | 32 | 2009-10-01 | 2014-02-25 |
Brain Neoplasms (7) · Breast Neoplasms (1) · Carcinoma, Non-Small-Cell Lung (1) · Glioblastoma (1) · Glioma (1) · Meningeal Neoplasms (1) · Neoplasms (1) · Stomach Neoplasms (1)
Brain Diseases (7) · Central Nervous System Diseases (7) · Central Nervous System Neoplasms (7) · Neoplasms by Site (7) · Nervous System Diseases (7) · Nervous System Neoplasms (7) · Neoplasms (6) · Astrocytoma (1) · Breast Diseases (1) · Bronchial Neoplasms (1) · Carcinoma, Bronchogenic (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Gastrointestinal Diseases (1) · Gastrointestinal Neoplasms (1)
Adrenal Cortex Hormones (1) · Blood Specimen Collection (1) · Dexamethasone (1) · Methylprednisolone (1) · Quality of Life (1) · Ritonavir (1) · Surveys and Questionnaires (1)
A2A Pharmaceuticals Inc. (1) · Iambic Therapeutics, Inc (1) · Jubilant Therapeutics Inc. (1) · National Taiwan University Hospital (1) · Philogen S.p.A. (1) · Radiopharm Theranostics, Ltd (1) · T-MAXIMUM Pharmaceutical Inc (1) · The Second Affiliated Hospital of Hainan Medical University (1) · University of California, San Francisco (1)
United States (5) · Italy (2) · United Kingdom (2) · China (1) · France (1) · Ireland (1) · Netherlands (1) · South Korea (1) · Spain (1) · Taiwan (1)
Dimitris Voliotis, MD (1) · Jean Nakamura, MD (1) · Paul Mullholand, Dr (1) · Secondo Lastoria, Dr (1)
2009 (1)