4 not yet recruiting, 1 active not recruiting, 1 completed. 6 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Not yet recruiting 4, Active not recruiting 1, Completed 1 |
| Phase 1 | 1 | Not yet recruiting 1 |
| Phase 3 | 1 | Not yet recruiting 1 |
Follow Brain Metastases From Solid Tumors: new trials by email Literature Review of Brain Metastases From Solid Tumors trials Research Report on Brain Metastases From Solid Tumors
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 1/2 Study Evaluating the Safety, PK/PD, and Clinical Activity of Oral JBI-778 in Patients With Brain Metastases, Leptomeningeal Disease, or Recurrent High Grade Glioma JBI-778 - Brain Metastases From Solid Tumors, Leptomeningeal Disease | Phase 1 / Phase 2 | Not yet recruiting | Jubilant Therapeutics Inc. | 113 | 2028-04-01 | 2026-08-07 |
| The METAMAX Study: MT027 Allogeneic CAR-T for Brain Metastases From Advanced Solid Tumors Intracerebroventricular injection of MT027 UCAR-T Cell targeting B7H3 - Brain Metastases From Solid Tumors | Phase 2 | Not yet recruiting | T-MAXIMUM Pharmaceutical Inc | 40 | 2027-12-30 | 2026-10-27 |
| Comparison of the Therapeutic Effects of Methylprednisolone and Dexamethasone on Peritumoral Edema During Radiotherapy for Brain Metastases: Methylprednisolone (Corticosteroid), Dexamethasone - Brain Metastases From Solid Tumors | Phase 2 / Phase 3 | Not yet recruiting | The Second Affiliated Hospital of Hainan Medical University | 400 | 2026-04-15 | 2026-04-21 |
| SMART Trial: Cognitive Sparing Brain Radiotherapy for Multiple Brain Metastases SRS, CS-WBRT, HA-WBRT - Brain Metastases From Solid Tumors | Phase 2 | Not yet recruiting | National Taiwan University Hospital | 90 | 2026-04-01 | 2026-04-13 |
| Phase 2b Imaging Study of RAD101 in Participants With Suspected Recurrent Brain Metastases RAD101 (18F-FPIA) - Brain Metastases From Solid Tumors | Phase 2 | Active not recruiting | Radiopharm Theranostics, Ltd | 30 | 2024-12-13 | 2026-08-12 |
| 131I-L19SIP Radioimmunotherapy (RIT) in Combination With External Beam Radiation in Patients With Multiple Brain Metastases From Solid Tumors 131I-L19SIP Radioimmunotherapy (RIT) in Combination With Whole Brain Radiation Therapy (WBRT) - Brain Metastases From Solid Tumors | Phase 2 | Completed | Philogen S.p.A. | 32 | 2009-10-01 | 2014-02-25 |
Brain Neoplasms (4) · Glioblastoma (1) · Glioma (1) · Meningeal Neoplasms (1)
Brain Diseases (4) · Central Nervous System Diseases (4) · Central Nervous System Neoplasms (4) · Neoplasms (4) · Neoplasms by Site (4) · Nervous System Diseases (4) · Nervous System Neoplasms (4) · Astrocytoma (1) · Neoplasms by Histologic Type (1) · Neoplasms, Germ Cell and Embryonal (1) · Neoplasms, Glandular and Epithelial (1) · Neoplasms, Nerve Tissue (1) · Neoplasms, Neuroepithelial (1) · Neuroectodermal Tumors (1)
Adrenal Cortex Hormones (1) · Dexamethasone (1) · Methylprednisolone (1) · Ritonavir (1)
Jubilant Therapeutics Inc. (1) · National Taiwan University Hospital (1) · Philogen S.p.A. (1) · Radiopharm Theranostics, Ltd (1) · T-MAXIMUM Pharmaceutical Inc (1) · The Second Affiliated Hospital of Hainan Medical University (1)
United States (2) · China (1) · Italy (1) · Taiwan (1) · United Kingdom (1)
Dimitris Voliotis, MD (1) · Paul Mullholand, Dr (1) · Secondo Lastoria, Dr (1)
2009 (1)