38 completed, 2 recruiting, 1 terminated, 1 unknown. 43 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 43 | Completed 38, Recruiting 2, Terminated 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow Bioavailability: new trials by email Literature Review of Bioavailability trials Research Report on Bioavailability
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Trigonelline Monohydrate on NAD+ Metabolism, Pharmacokinetics, Safety, and Tolerability in Healthy Adults Nicotinamide Mononucleotide (NMN), Placebo, Trigonelline Monohydrate - NAD+ Metabolism, Pharmacokinetics | Phase 1 | Recruiting | dsm-firmenich Switzerland AG | 60 | 2026-11-01 | 2026-11-05 |
| A Bioequivalence Study of Advil Tablet (Mini) (Ibuprofen 200 mg) Versus Advil Tablet (Ibuprofen 200 mg) in Healthy Adult Subjects Under Fasted Conditions and Bioavailability Assessment of Advil Tablet (Mini) Under Fed Conditions Advil Tablet (Mini) (Test Product), Advil Tablet (Reference Product) - Bioequivalence, Bioavailability | Phase 1 | Completed | HALEON | 68 | 2025-12-17 | 2026-09-23 |
| Study on Sapropterin Dihydrochloride Oral Suspension in Healthy Subjects RLF-OD032, Kuvan - Bioavailability | Phase 1 | Completed | APR Applied Pharma Research s.a. | 16 | 2024-07-30 | 2025-06-12 |
| Relative Bioavailability and Effect of Food Study With an Oral Mini-tablet Formulation of Filgotinib in Healthy Subjects Filgotinib - Bioavailability | Phase 1 | Completed | Lakefront Biotherapeutics NV | 12 | 2023-09-22 | 2023-11-29 |
| Curcumin and Retinal Study Low curcumin group, High curcumin group - Bioavailability, Gut Microbiome | Phase 1 / Phase 2 | Recruiting | Texas Tech University Health Sciences Center | 60 | 2023-08-21 | 2026-01-13 |
| Bioavailability Study to Compare Liquid vs Two Solid Formulations of IP2015 IP2015 - Bioavailability | Phase 1 | Unknown | Initiator Pharma | 12 | 2023-02-16 | 2023-02-15 |
| Relative Bioavailability of Linaprazan for the Test Formulation vs. Reference Formulation Linaprazan glurate - Safety, Bioavailability | Phase 1 | Completed | Cinclus Pharma Holding AB | 67 | 2022-11-15 | 2025-04-03 |
| Bioavailability Study of EVEGYN 600 mg/1000 mg/100 mg Vaginal Ovule EVEGYN 600 mg/1000 mg/100 mg Vaginal Ovule - Bioavailability | Phase 1 | Completed | Exeltis Turkey | 18 | 2022-05-09 | 2025-02-07 |
| Relative Bioavailability Study of PF-07321332/Ritonavir Oral Powder Relative to the Commercial Tablets in Healthy Participants PF-07321332/ritonavir - Bioavailability | Phase 1 | Completed | Pfizer | 12 | 2022-03-10 | 2024-06-06 |
| Relative Bioavailability Study of 4 Different Formulations of PF-07321332 Relative to the Commercial Tablet Formulation PF-07321332/ritonavir, PF-07321332 - Bioavailability | Phase 1 | Completed | Pfizer | 12 | 2022-03-03 | 2025-06-11 |
| Atoguanil BA Study Atoguanil, Malarone - Bioavailability | Phase 1 | Completed | Medicines for Malaria Venture | 16 | 2021-11-17 | 2022-05-05 |
| Study of CT001 in Healthy Volunteers CT001, Ketamine, sufentanil - Bioavailability | Phase 1 | Completed | Cessatech A/S | 14 | 2021-03-17 | 2021-08-24 |
| A Study of TEPEZZA Subcutaneous Administration in Healthy Adults TEPEZZA, EDP - Bioavailability, Bioequivalence | Phase 1 | Completed | Amgen | 37 | 2020-09-22 | 2024-08-21 |
| A Study to Evaluate Relative Bioavailability, Proton Pump Inhibitor (PPI) (Rabeprazole) Effect, Food Effect and Particle Size Effect of New Acalabrutinib Tablet in Healthy Subjects Treatment A- Part 1, Treatment B- Part 1, Treatment C - Part 1 - Bioavailability, B-cell Lymphoid Cancer | Phase 1 | Completed | AstraZeneca | 54 | 2020-06-24 | 2021-02-03 |
| A Study of Acalabrutinib Suspension to Evaluate Relative Bioavailability and Proton-pump Inhibitor Effect in Healthy Volunteers Acalabrutinib Treatment A, Acalabrutinib Treatment B, Acalabrutinib Treatment C - Pharmacokinetics, Bioavailability | Phase 1 | Completed | AstraZeneca | 39 | 2020-05-22 | 2020-07-22 |
| A Study to Investigate Differences in the Extent and Rate of Absorption of Doxylamine/Pyridoxine From 2 Different Products Under Fasting Conditions doxylamine succinate 10 mg/pyridoxine hydrochloride 10 mg combination, Diclegis (Registered Trademark) - Bioavailability | Phase 1 | Withdrawn | Grünenthal GmbH | 2019-06-01 | 2019-07-11 | |
| Evaluating the Pharmacokinetic Parameters and Relative Bioavailability of Sorafenib (XS005) in Healthy Male Subjects Sorafenib - Period 1, XS005 Sorafenib Capsule A - Period 1, XS005 Sorafenib Tablet A - Period 1 - Pharmacokinetics, Bioavailability | Phase 1 | Completed | Xspray Pharma AB | 15 | 2018-11-16 | 2023-08-01 |
| Oxandrolone in Healthy Adults: A Relative Bioavailability Study Oxandrin - Bioavailability | Phase 1 | Completed | University of Utah | 6 | 2017-07-10 | 2018-05-03 |
| A Study to Assess the Bioavailability of Oral Sodium Oligo-mannurarate (GV-971) in Healthy Chinese Male Subjects GV-971, Placebos - Bioavailability | Phase 1 | Completed | Shanghai Greenvalley Pharmaceutical Co., Ltd. | 15 | 2016-11-01 | 2018-02-07 |
| Bioavailability and Effect of Food on DSM265 Granules in Healthy Adult Subjects DSM265 50% SDD granules, DSM265 25% SDD powder for suspension - Healthy Volunteers, Bioavailability | Phase 1 | Terminated | Medicines for Malaria Venture | 11 | 2016-05-01 | 2016-09-14 |
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COVID-19 (2) · Fasting (1) · Graves Ophthalmopathy (1) · HIV Infections (1) · Malaria (1) · Smoking Cessation (1)
Infections (4) · RNA Virus Infections (3) · Virus Diseases (3) · Behavior (2) · Coronaviridae Infections (2) · Coronavirus Infections (2) · Immune System Diseases (2) · Lung Diseases (2) · Nidovirales Infections (2) · Pneumonia (2) · Pneumonia, Viral (2) · Respiratory Tract Diseases (2) · Respiratory Tract Infections (2) · Autoimmune Diseases (1) · Blood-Borne Infections (1)
Excipients (2) · Famotidine (2) · Water (2) · mirabegron (2) · naloxegol (2) · nirmatrelvir and ritonavir drug combination (2) · DSM265 (1) · Dexlansoprazole (1) · Dronabinol (1) · GLPG0634 (1) · GV-971 (1) · Gemfibrozil (1) · Ibuprofen (1) · Ketamine (1) · Ketoconazole (1)
AstraZeneca (6) · Pfizer (4) · Labopharm Inc. (2) · Medicines for Malaria Venture (2) · Perrigo Company (2) · APR Applied Pharma Research s.a. (1) · Amgen (1) · Astellas Pharma Europe B.V. (1) · Astellas Pharma Inc (1) · Bayer (1) · Blu Caribe (1) · Cessatech A/S (1) · Cinclus Pharma Holding AB (1) · Endo USA Inc., a Keenova Therapeutics Company (1) · Exeltis Turkey (1)
United States (19) · Canada (4) · Germany (3) · United Kingdom (3) · China (1) · Denmark (1) · Netherlands (1) · Singapore (1) · Slovenia (1) · Turkey (Türkiye) (1)
Rainard Fuhr, Dr. med. (2) · Ashima Bhatia, MD (1) · Benoit Deschamps, MD (1) · Bo Fransson, MD (1) · Carlos Prendes, MD (1) · David Han, M.D. (1) · David Matthews, MD (1) · Gabriele Civiletto (1)
PMID 19774117, PMID 20051587, PMID 32757149, PMID 37231296, PMID 38918235
2015 (1)