592 completed. 592 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 592 | Completed 592 |
Follow Autoimmune Diseases: new trials by email Literature Review of Autoimmune Diseases trials Research Report on Autoimmune Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Randomized Transition to Gla-300 in Pediatric Type 1 Diabetes: CGM-Derived Outcomes Insulin glargine U-300 - Type 1 Diabetes Mellitus | Phase 4 | Completed | Marmara University | 71 | 2025-05-01 | 2026-10-13 |
| Efficacy of Tofacitinib on Skin Thickening in Diffuse Cutaneous Systemic Sclerosis: A Comparative Study With Methotrexate Tofacitinib, Methotrexate - Scleroderma, Systemic | Phase 4 | Completed | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 34 | 2024-12-21 | 2026-03-16 |
| A Study to Assess Adults With CIDP Transitioning From IVIg to Efgartigimod PH20 SC Efgartigimod PH20 SC - Chronic Inflammatory Demyelinating Polyneuropathy | Phase 4 | Completed | argenx | 23 | 2024-12-10 | 2026-04-06 |
| A Study of Filgotinib in Korean Participants With Rheumatoid Arthritis Filgotinib Maleate - Rheumatoid Arthritis | Phase 4 | Completed | Eisai Korea Inc. | 118 | 2024-10-22 | 2026-05-11 |
| Evaluating the Efficacy and Quality of Life Impact of Transitioning to Advanced Hybrid Closed-Loop Insulin Pump Therapy in Romanian Children With Type 1 Diabetes Mellitus Switching to the Medtronic 780G insulin pump - Diabetes Mellitus, Type 1 | Phase 4 | Completed | ELIAS Emergency University Hospital | 30 | 2024-03-11 | 2026-09-29 |
| Comparative Study of Leflunomide Plus Methotrexate Versus Methotrexate Monotherapy in Refractory Polyarticular Juvenile Idiopathic Arthritis Patients Leflunomide plus Methotrexate, Methotrexate Monotherapy - Juvenile Idiopathic Arthritis, Polyarticular Juvenile Idiopathic Arthritis | Phase 4 | Completed | Bangladesh Medical University | 50 | 2024-03-01 | 2026-02-23 |
| Efficacy and Safety of add-on Dapsone Versus add-on Methotrexate in Patients With Bullous Pemphigoid Prednisolone, Dapsone, Methotrexate - Bullous Pemphigoid | Phase 4 | Completed | All India Institute of Medical Sciences, Bhubaneswar | 62 | 2023-08-01 | 2025-08-14 |
| Teplizumab in Pediatric Stage 2 Type 1 Diabetes teplizumab - Diabetes Mellitus, Type 1 | Phase 4 | Completed | Sanofi | 23 | 2023-07-25 | 2026-09-29 |
| INHALE-3: Afrezza® Combined With Insulin Degludec Versus Usual Care in Adults With Type 1 Diabetes Afrezza, insulin degludec, Rapid-acting Insulin Analog - Diabetes Mellitus, Type 1 | Phase 4 | Completed | Mannkind Corporation | 141 | 2023-07-07 | 2024-08-09 |
| Comparative Efficacy of a Two Daily Mixed Insulin Injection Versus a Basal-bolus Scheme With Human Insulin premix insulin human isophane suspension and insulin human, Humulin N plus Humulin R - Type 1 Diabetes | Phase 4 | Completed | Université NAZI BONI | 22 | 2023-06-15 | 2024-12-12 |
| A Study of Dimethyl Fumarate (DMF) in Relapsing Forms of Multiple Sclerosis (RMS) Participants in China Dimethyl fumarate - Multiple Sclerosis | Phase 4 | Completed | Biogen | 60 | 2023-06-09 | 2025-05-16 |
| Nasal Spray Study in Sjogren's Dry Eye Disease Varenicline Nasal Spray - Sjogren's Syndrome, Dry Eye | Phase 4 | Completed | University of Pennsylvania | 39 | 2023-05-01 | 2024-11-05 |
| Human Versus Analogue Insulin for Youth With Type 1 Diabetes in Low-Resource Settings Insulin Glargine, NPH or premixed 70/30 (human insulin) - Diabetes Mellitus, Type 1, Type 1 Diabetes | Phase 4 | Completed | Jing Luo | 400 | 2023-03-15 | 2025-09-10 |
| A Randomized Trial Comparing Optimized rhTPO Treatment With Eltrombopag Treatment in Pre-treated ITP Pts rhTPO, Eltrombopag - Previously Treated Primary Immune Thrombocytopenia | Phase 4 | Completed | Institute of Hematology & Blood Diseases Hospital, China | 157 | 2022-11-22 | 2025-04-24 |
| Ketone Monitoring in T1D: Effect of SGLT2i During Usual Care and With Insulin Deficiency SGLT2 inhibitor, Biosense Breath Ketone Analyzer - Diabetes Mellitus, Type 1 | Phase 4 | Completed | Washington University School of Medicine | 21 | 2022-10-14 | 2025-02-21 |
| SGLT2 Inhibitors Between Reno Protective Effects and Impact on Bone and Mineral Disease Among Lupus Nephritis Patients Dapagliflozin tablet, placebo - SGLT2 INHIBITORS, Lupus Nephritis | Phase 4 | Completed | Mansoura University | 100 | 2022-10-08 | 2024-10-15 |
| Efficacy and Safety of Baricitinib for the Treatment of Moderate to Severe Rheumatoid Arthritis Baricitinib 4 MG Oral Tablet, Baricitinib 2 MG - Rheumatoid Arthritis | Phase 4 | Completed | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 94 | 2022-10-01 | 2023-11-18 |
| Cardio Renal Effects of SGLT2 Inhibitors Among Lupus Nephritis Patients dapagliflozin, placebo - SLE, Lupus Nephritis | Phase 4 | Completed | Mansoura University | 84 | 2022-10-01 | 2025-04-16 |
| Impact of Introducing Basaglar Insulin to the Treatment Regimen of Youth With Diabetes in Pakistan biosimilar insulin glargine - Type 1 Diabetes | Phase 4 | Completed | Life for a Child Program, Diabetes Australia | 296 | 2022-06-09 | 2025-07-30 |
| Evaluating the Impact of Introducing Basaglar, a Long-acting Analog Insulin, on Clinical and Quality of Life Outcomes in Youth with Diabetes in Bangladesh biosimilar insulin glargine - Type I Diabetes | Phase 4 | Completed | Life for a Child Program, Diabetes Australia | 202 | 2022-06-01 | 2024-11-07 |
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Arthritis, Rheumatoid (191) · Diabetes Mellitus, Type 1 (140) · Multiple Sclerosis (103) · Multiple Sclerosis, Relapsing-Remitting (45) · Diabetes Mellitus (42) · Lupus Erythematosus, Systemic (27) · Arthritis, Juvenile (14) · Diabetes Mellitus, Type 2 (13) · Insulin Resistance (13) · Glomerulonephritis, IGA (12) · Proteinuria (12) · Graves Disease (11) · Hypoglycemia (11) · Purpura, Thrombocytopenic, Idiopathic (11)
Immune System Diseases (591) · Skin and Connective Tissue Diseases (256) · Connective Tissue Diseases (243) · Musculoskeletal Diseases (217) · Joint Diseases (211) · Rheumatic Diseases (210) · Arthritis (203) · Endocrine System Diseases (165) · Nutritional and Metabolic Diseases (150) · Nervous System Diseases (149) · Metabolic Diseases (148) · Glucose Metabolism Disorders (143) · Autoimmune Diseases of the Nervous System (137) · Demyelinating Diseases (134)
Methotrexate (60) · Etanercept (34) · Adalimumab (32) · Insulin Aspart (28) · tocilizumab (27) · Insulin Glargine (24) · Rituximab (24) · Interferon beta-1a (23) · Prednisone (19) · Methylprednisolone (18) · Insulin (16) · Insulin Lispro (16) · Fingolimod Hydrochloride (15) · Abatacept (14) · insulin glulisine (14)
Hoffmann-La Roche (28) · Biogen (24) · Sanofi (20) · Novartis Pharmaceuticals (18) · Amgen (15) · Novo Nordisk A/S (11) · University of Colorado, Denver (9) · Pfizer (8) · Merck KGaA, Darmstadt, Germany (7) · Assistance Publique - Hôpitaux de Paris (6) · Medical University of Warsaw (6) · Steno Diabetes Center Copenhagen (6) · University of Sao Paulo General Hospital (6) · Wyeth is now a wholly owned subsidiary of Pfizer (6) · Astellas Pharma Inc (5)
United States (189) · France (65) · United Kingdom (55) · Germany (52) · Canada (43) · Spain (41) · China (40) · Italy (39) · Denmark (33) · Sweden (31) · Netherlands (30) · Belgium (28) · Poland (28) · Austria (25) · Czechia (25)
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