12 recruiting. 12 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 12 | Recruiting 12 |
| Phase 1 | 2 | Recruiting 2 |
Follow Atrophy: new trials by email Literature Review of Atrophy trials Research Report on Atrophy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Study of TJ0113 Capsule in the Treatment of Patients With Sarcopenia TJ0113, Placebo - Sarcopenia | Phase 2 | Recruiting | Hangzhou PhecdaMed Co., Ltd. | 204 | 2026-06-12 | 2026-08-05 |
| CALM-AF-AI: Counteracting Age-related Loss of Muscle With AAV-Follistatin Combined With Angiogenesis-Inducing VEGF Plasmid Gene Therapy AAV9-Follistatin gene therapy, VEGF Plasmid - Age-related Muscle Decline | Phase 1 / Phase 2 | Recruiting | Unlimited Biotechnology LLC | 12 | 2026-06-01 | 2026-07-13 |
| A Study of PLH-2301 in Subjects With Sarcopenia PLH-2301, Placebo - Sarcopenia in Elderly | Phase 2 | Recruiting | Pluto Inc. | 168 | 2026-05-08 | 2026-05-12 |
| Clinical Trial of CG-BM1 Allogeneic Human Bone Marrow Mesenchymal Stem Cell Injection in the Treatment of Sarcopenia CG-BM1- 5.0 × 10^7 cells, CG-BM1-1.0 × 10^8 cells - Sarcopenia | Phase 1 / Phase 2 | Recruiting | GuangZhou Cellgenes Biotechnology Co., Ltd. | 30 | 2026-04-30 | 2026-10-14 |
| Effects of Tirzepatide on Muscle and Vascular Health in Obese Older Adults Tirzepatide - Obesity Prevention, Sarcopenia in Elderly | Phase 2 | Recruiting | The University of Texas Health Science Center at San Antonio | 20 | 2026-04-01 | 2026-04-15 |
| Subdermal Implant-bioabsorbable Oxandrolone Pellet For Rehabilitation Following Anterior Cruciate Ligament (ACL) Surgical Reconstruction Oxandrolone, Placebo - Anterior Cruciate Ligament (ACL) Reconstruction | Phase 2 | Recruiting | Science Valley Research Institute | 96 | 2025-11-28 | 2026-08-25 |
| A Study of AMC6156 in People With Sarcopenia AMC6156 0.1mg, AMC6156 0.3mg, AMC6156 1.0mg - Sarcopenia in Elderly, Sarcopenia | Phase 2 | Recruiting | Animuscure Inc. | 80 | 2025-07-01 | 2026-08-03 |
| A Study of the Effect of (S)-Pindolol Benzoate (ACM-001.1) on Lean Body Mass (LBM) in Obese Patents During (PROACT 1), and Post-semaglutide Therapy (PROACT 2) (S)-pindolol benzoate, Semaglutide, Placebo to (S)-pindolol benzoate - Obesity, Muscle Loss | Phase 2 | Recruiting | Actimed Therapeutics Ltd | 120 | 2025-06-23 | 2026-02-17 |
| Essential Amino Acid Supplementation for Femoral Fragility Fractures Essential Amino Acid Supplementation - Femoral Fracture, Fragility Fracture | Phase 2 | Recruiting | Michael C Willey | 60 | 2024-06-17 | 2026-10-07 |
| Study of the Effectiveness of Treatment of Sarcopenia With the Use of a Medicinal Product (Nandrolone), Comprehensive Physiotherapy and Diet Nandrolone Decanoate, Physiotherapy Intervention, Nutritional Intervention - Sarcopenia | Phase 2 | Recruiting | National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland | 168 | 2023-08-10 | 2026-04-08 |
| Influence of β-hydroxy β-methyl Butyrate (HMB)Supplementation on Post-operative Muscle Mass and Function in Female Athletes CaHMB (Dietary supplement, not Drug), CaLa - Atrophy | Phase 2 | Recruiting | University of Kansas Medical Center | 30 | 2023-05-29 | 2026-03-02 |
| Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors Nicotinamide Riboside, Placebo, Exercise Intervention - Lymphoblastic Leukemia, Cancer Survivors | Phase 2 | Recruiting | Children's Hospital of Philadelphia | 80 | 2023-02-23 | 2025-12-04 |
Sarcopenia (9) · Muscular Atrophy (3) · Obesity (2) · Anemia, Aplastic (1) · Femoral Fractures (1) · Frailty (1) · Leukemia, Myeloid (1) · Muscle Weakness (1) · Myelodysplastic Syndromes (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1) · Weight Loss (1)
Pathological Conditions, Anatomical (12) · Pathological Conditions, Signs and Symptoms (12) · Nervous System Diseases (11) · Neurologic Manifestations (11) · Neuromuscular Manifestations (11) · Signs and Symptoms (11) · Muscular Atrophy (8) · Body Weight (2) · Nutrition Disorders (2) · Nutritional and Metabolic Diseases (2) · Overnutrition (2) · Overweight (2) · Anemia (1) · Body Weight Changes (1)
Dietary Supplements (1) · Nandrolone Decanoate (1) · Oxandrolone (1) · Tirzepatide (1) · beta-hydroxyisovaleric acid (1) · calcium lactate (1) · nicotinamide-beta-riboside (1) · semaglutide (1)
Actimed Therapeutics Ltd (1) · Animuscure Inc. (1) · Children's Hospital of Philadelphia (1) · GuangZhou Cellgenes Biotechnology Co., Ltd. (1) · Hangzhou PhecdaMed Co., Ltd. (1) · Michael C Willey (1) · National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland (1) · Pluto Inc. (1) · Science Valley Research Institute (1) · The University of Texas Health Science Center at San Antonio (1) · University of Kansas Medical Center (1) · Unlimited Biotechnology LLC (1)
United States (4) · China (2) · South Korea (2) · Brazil (1) · Honduras (1) · Poland (1) · Serbia (1)
Eduardo Ramacciotti, MD, PhD (1) · Elena Volpi, MD, PhD (1) · Michael C Willey, MD (1) · Qin Zhang (1) · Roberto Tauchmann, MD (1) · Shreya Rao, MD, MPH (1) · Sogol Mostoufi-Moab, MD, MSCE (1) · Sun Ahe Lee (1) · Tiffany Cortes, MD (1) · Tomasz Targowski, Prof. PhD, MD (1)
R01CA254955 (1)