6 completed, 4 recruiting, 4 unknown, 2 not yet recruiting. 9 Not applicable, 3 Phase 4, 1 Phase 1, 1 Phase 2, 1 Phase 3.
Follow Asthma Exacerbation: new trials by email Literature Review of Asthma Exacerbation trials Research Report on Asthma Exacerbation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Development and Validation of the Indian Asthma Care Bundle for Reducing Readmission and Improving Post-hospitalisation Care After Discharge From Hospital Due to an Acute Asthma Exacerbation Indian Asthma Care Bundle (I-ACB) - Asthma Exacerbation, Asthma (Diagnosis) | Not applicable | Not yet recruiting | Ahmedabad University | 260 | 2026-12-01 | 2026-09-11 |
| Efficacy of High-Dose Continuous Intravenous Magnesium Sulfate Infusion vs Standard Intravenous Magnesium Sulfate Therapy in Status Asthmaticus in the ED ้High-dose Magnesium sulphate, standard-dose Magnesium Sulfate - Asthma Exacerbation, Emergency Department | Not applicable | Not yet recruiting | Thammasat University | 72 | 2026-11-01 | 2026-08-31 |
| Combination of High-flow Nasal Oxygen (Optiflow) and Vibrating Membrane Nebuliser (Aerogen) in the Pre-hospital Setting - Before/After Study Vibrating membrane nebulizer and high-intensity nasal oxygen, nebulizer mask and oxygen therapy of 6 to 9 liters per minute - Hypercapnia, Asthma Exacerbation | Withdrawn | Centre Hospitalier Sud Francilien | 2026-10-01 | 2026-08-28 | ||
| Pollution Intervention to Impact Kids Asthma Study EPA-AQI, Commerical-AQI, Education and plan - Childhood Asthma, Asthma Control | Not applicable | Recruiting | University of Pittsburgh | 351 | 2026-02-24 | 2026-02-27 |
| RIG 101 Trial in Healthy Adults and Adults With Asthma RIG-101, Placebo - Healthy Adult Participants, Asthma Exacerbation | Phase 1 / Phase 2 | Recruiting | RIGImmune Inc. | 82 | 2026-02-09 | 2026-09-09 |
| 45th Multicenter Airway Research Collaboration Airsupra - Asthma Acute, Asthma Exacerbation | Phase 4 | Recruiting | Massachusetts General Hospital | 1860 | 2025-11-07 | 2026-04-17 |
| Evaluation of the Medentum Diagnostik Platform for Pediatric ENT Conditions and Asthma Diagnostik home-based platform: multisensor device, software application, and artificial-intelligence algorithms that predict diagnosis of AOM and strep pharyngitis, Diagnostik home-based platform: multisensor device, software application, and artificial-intelligence algorithms that predict diagnosis of wheeze/asthma exacerbation, Routine Asthma Management (in-person and telehealth visits)- Control Group - Acute Otitis Media (AOM), Strep Pharyngitis | Not applicable | Recruiting | Medentum Innovations | 84 | 2025-10-01 | 2026-03-30 |
| Continuous Versus Intermittent Nebulization Therapy in Acute Asthma Exacerbation at Emergency Department continuous nebulization, Intermittent nebulization - Asthma Exacerbation, Emergency Department | Not applicable | Unknown | Thammasat University | 40 | 2024-04-01 | 2024-03-04 |
| A Comparative Study of Adding Ipratropium to Salbutamol for the Treatment of Asthma Attack in Children Salbutamol (Ventolin®), salbutamol + ipratropium bromide nebules - Asthma Exacerbation, Children | Phase 4 | Completed | Children's Hospital and Institute of Child Health, Multan | 60 | 2024-01-01 | 2025-04-09 |
| A Study Evaluating the Use of ResAppDx v2.0 as an Aid to Diagnose Respiratory Disease in Adolescent and Adult Patients in an Emergency Department ResAppDx v.20 - Asthma Exacerbation, COPD Exacerbation | Completed | ResApp Health Limited | 171 | 2024-01-01 | 2024-03-04 | |
| Application of Telehealth Technology in Asthma Management CANATEXTS - Asthma Exacerbation, Quality of Life | Not applicable | Unknown | University of British Columbia | 620 | 2023-03-01 | 2022-08-02 |
| Diagnosing Respiratory Disease in Children Using Cough Sounds 2 Recordings of Infants and Children's Cough Sounds - Pneumonia, Bronchiolitis | Completed | ResApp Health Limited | 1470 | 2018-01-05 | 2018-11-08 | |
| Asthma Research in Children and Adolescents Inhaled Corticosteroids (ICs), Fixed-Dose Combination of Inhaled Corticosteroids and Long- Acting Beta-agonist (ICs/LABA), Other treatments - Persistent Asthma, Asthma in Children | Active not recruiting | Parc de Salut Mar | 525 | 2017-07-26 | 2025-07-31 | |
| Effectiveness of the Aeroneb in Acute Severe Asthma Aeroneb nebulizer, Small volume jet nebulizer - Asthma Exacerbation | Not applicable | Completed | Tufts Medical Center | 31 | 2015-08-01 | 2023-05-19 |
| Study of Preventive Treatment With Symbicort or Budicort Turbohaler in Childhood Asthma Return to School Epidemic Budesonide turbuhaler, Budesonide+Formoterol turbuhaler - Asthma Exacerbation | Not applicable | Unknown | Meir Medical Center | 225 | 2010-09-01 | 2012-03-19 |
| Pilot Study of How Children With Asthma Exacerbations Metabolize Prednisone Prednisolone and prednisone - Asthma Exacerbation | Completed | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 20 | 2009-09-09 | 2017-08-28 | |
| Asthma Exacerbation and Helium-3 MRI Helium-3 - Asthma Exacerbation | Not applicable | Withdrawn | University of Massachusetts, Worcester | 2009-01-01 | 2012-09-20 | |
| Treatment of Acute Asthma in ER With Combination of Systemic Steroids and Inhaled Steroids inhalation of corticosteroids - Asthma Exacerbation | Phase 4 | Unknown | Soroka University Medical Center | 120 | 2007-01-01 | 2006-11-28 |
| Reduction in Clinical Variance Using Targeted Design Changes in Computerized Provider Order Entry Order (CPOE) Sets Evidence Based Intervention to order set - Asthma Exacerbation | Phase 3 | Completed | Brian Jacobs | 458 | 2004-09-01 | 2015-05-21 |
Asthma (9) · Emergencies (3) · Pneumonia (2) · Bronchiolitis (1) · Cough (1) · Croup (1) · Disease (1) · Dyspnea (1) · Hypercapnia (1) · Medication Adherence (1) · Otitis Media (1) · Pulmonary Disease, Chronic Obstructive (1) · Respiration Disorders (1) · Risk Reduction Behavior (1)
Respiratory Tract Diseases (12) · Lung Diseases (11) · Bronchial Diseases (10) · Lung Diseases, Obstructive (10) · Hypersensitivity (9) · Hypersensitivity, Immediate (9) · Immune System Diseases (9) · Respiratory Hypersensitivity (9) · Pathological Conditions, Signs and Symptoms (7) · Pathologic Processes (5) · Disease Attributes (4) · Behavior (2) · Infections (2) · Otorhinolaryngologic Diseases (2) · Respiratory Tract Infections (2)
Albuterol (1) · Educational Status (1) · Helium-3 (1) · Ipratropium (1) · Magnesium Sulfate (1) · Prednisolone (1) · Prednisone (1)
ResApp Health Limited (2) · Thammasat University (2) · Ahmedabad University (1) · Brian Jacobs (1) · Centre Hospitalier Sud Francilien (1) · Children's Hospital and Institute of Child Health, Multan (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · Massachusetts General Hospital (1) · Medentum Innovations (1) · Meir Medical Center (1) · Parc de Salut Mar (1) · RIGImmune Inc. (1) · Soroka University Medical Center (1) · Tufts Medical Center (1) · University of British Columbia (1)
United States (7) · Canada (2) · Israel (2) · United Kingdom (2) · France (1) · India (1) · Pakistan (1) · Spain (1)
Avner He Cohen, Dr (1) · Chris Carlsten, M.D. (1) · Dov Heimer, M.D (1) · Dr. Muhammad Aslam Sheikh, FCPS (1) · Franziska Rosser, MD MPH (1) · Kumpol Kornthatchapong (1) · Michael Rieder, MD, Ph.D, FRCPC (1) · Mitchell S Albert, Ph.D. (1) · Montse Ferrer Fores, MD,PhD (1) · Nicholas S Hill, MD (1) · Peter P Moschovis, MD, MPH (1) · Subhabrata Moitra, PhD (1)
PMID 10334138, PMID 10785582, PMID 14713908, PMID 1549827, PMID 17654487, PMID 19070357, PMID 19767070, PMID 23244616, PMID 24565623, PMID 25439365, PMID 25869584, PMID 25948889, PMID 26123420, PMID 27056585, PMID 29150201, PMID 29970764, PMID 29970770, PMID 30219316, PMID 31208388, PMID 31613151, PMID 31772002, PMID 34265445, PMID 34593626, PMID 37087095, PMID 37333684, PMID 37886027, PMID 40216760, PMID 40229553, PMID 40236314, PMID 40295741, PMID 40562420, PMID 40707071, PMID 9431328
R01ES036965 (1)