313 completed. 313 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 313 | Completed 313 |
Follow Asthma: new trials by email Literature Review of Asthma trials Research Report on Asthma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| IV DEXAMETHASONE VS. METHYLPREDNISOLONE IN CHILDREN WITH SEVERE ASTHMA EXACERBATION Intravenous Dexamethasone, Intravenous Methylprednisolone - Status Asthmaticus, Asthma (Diagnosis) | Phase 4 | Completed | Istanbul Medeniyet University | 129 | 2025-09-01 | 2026-07-28 |
| Establish FeNO Cut-off Value for Predicting Budesonide-formoterol Response in Chronic Cough Suggestive of CVA Patients. Budesonide-Formoterol treatment - Cough-Variant Asthma | Phase 4 | Completed | AstraZeneca | 1000 | 2024-10-18 | 2025-09-18 |
| Study to Investigate Changes in Airway Inflammation, Symptoms, and Rescue Therapy Utilization With AIRSUPRA Compared to Albuterol as Needed in Adults With Mild Asthma Albuterol/Budesonide, Albuterol - Mild Asthma | Phase 4 | Completed | AstraZeneca | 101 | 2024-09-11 | 2026-02-27 |
| Evaluation of Time-Sensitive Nebulization Mode Converter Cross-over Nebulization Modes Comparison System - Aerosol Therapy, Asthma | Phase 4 | Completed | Beni-Suef University | 36 | 2024-09-01 | 2026-06-08 |
| A Pilot Study of Mirabegron and Montelukast in Cirrhotic Patients Mirabegron 100 mg, Mirabegron 50mg, mirabegron 25 mg - Cirrhosis, Asthma | Phase 4 | Completed | Kafrelsheikh University | 78 | 2024-07-01 | 2026-04-16 |
| BenRalizumab Effect on Airway Remodeling in Severe asTHma Benralizumab 30 mg/ml - Asthma; Eosinophilic, Airway Remodeling | Phase 4 | Completed | Aristotle University Of Thessaloniki | 36 | 2024-03-01 | 2026-10-28 |
| Bioequivalence Study of Methacholine for Inhalation (pharmacodynamics) Test preparation：Methylcholine chloroacetate for inhalation, Reference preparation：Methylcholine chloroacetate for inhalation（Provocholine） - Asthma | Phase 4 | Completed | China-Japan Friendship Hospital | 40 | 2024-02-24 | 2024-12-10 |
| Individualizing Treatment for Asthma in Primary Care Asthma Symptom Monitoring online tools, Inhaled Steroids, Azithromycin Pill - Asthma, Bronchial Diseases | Phase 4 | Completed | DARTNet Institute | 103 | 2024-02-01 | 2025-04-20 |
| Reversibility of Methacholine Induced Bronchoconstriction salbutamol aqueous solution, salbutamol pressurized metered dose inhaler, placebo - Asthma | Phase 4 | Completed | University of Saskatchewan | 16 | 2024-01-12 | 2026-05-04 |
| A Comparative Study of Adding Ipratropium to Salbutamol for the Treatment of Asthma Attack in Children Salbutamol (Ventolin®), salbutamol + ipratropium bromide nebules - Asthma Exacerbation, Children | Phase 4 | Completed | Children's Hospital and Institute of Child Health, Multan | 60 | 2024-01-01 | 2025-04-09 |
| ICS+LABA Vs. ICS+LABA+Omalizumab: Impact on Asthma Control and Gene Expression Foster BDP/Formoterol, Omalizimab - Asthma Patients | Phase 4 | Completed | Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation | 26 | 2023-01-01 | 2025-03-11 |
| BURAN: Benralizumab on Airway Dynamics in Severe Eosinophilic Asthma Using Functional Respiratory Imaging Benralizumab - Asthma | Phase 4 | Completed | AstraZeneca | 45 | 2022-10-11 | 2025-03-25 |
| CARE FOR ALL：an Evaluation of an Asthma QIP QIP intervention - Asthma | Phase 4 | Completed | AstraZeneca | 1500 | 2022-07-29 | 2026-01-02 |
| Periostin-guided Withdrawal of Inhaled Corticosteroids in Patients With Non-eosinophilic Asthma Tapering of inhaled corticosteroid (ICS) treatment - Asthma | Phase 4 | Completed | Hvidovre University Hospital | 20 | 2022-06-01 | 2025-03-17 |
| Effectiveness and Safety Study of Tezepelumab in Adults & Adolescent Participants With Severe Asthma in the United States Tezepelumab - Asthma | Phase 4 | Completed | AstraZeneca | 286 | 2022-04-29 | 2026-07-16 |
| Sensory-Mechanical Responses to Eucapneic Voluntary Hyperventilation and Mannitol Methacholine (MCh) Challenge Testing, Eucapneic Voluntary Hyperventilation (EVH), Mannitol Inhalation Kit - Asthma, Cough | Phase 4 | Completed | Dr. Diane Lougheed | 45 | 2022-03-01 | 2026-08-12 |
| Effects of Interleukin (IL)- 4R-alpha Inhibition on Respiratory Microbiome and Immunologic Correlates in Severe Asthma Dupilumab - Asthma | Phase 4 | Completed | University of Michigan | 15 | 2022-02-22 | 2024-10-23 |
| Mepolizumab for the Treatment of Chronic Cough With Eosinophilic Airways Diseases Mepolizumab, Normal Saline - Chronic Cough, Eosinophilic Bronchitis | Phase 4 | Completed | McMaster University | 46 | 2021-12-14 | 2025-09-16 |
| Regular Use Tiotropium and Tolerance to Bronchoprotection in Mild Asthma Tiotropium Bromide, Matching placebo - Asthma | Phase 4 | Completed | University of Saskatchewan | 12 | 2021-12-13 | 2022-05-23 |
| Use of Buventol Easyhaler and Bufomix Easyhaler in Methacoline Challenge Testing Buventol® Easyhaler® 200 µg/inhalation dmDPI, Bufomix® Easyhaler® 160/4.5 µg/inhalation dmDPI, Ventoline® Evohaler® 100 µg/inhalation pMDI - Asthma | Phase 4 | Completed | Orion Corporation, Orion Pharma | 180 | 2021-11-11 | 2023-09-05 |
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Pulmonary Disease, Chronic Obstructive (18) · Rhinitis, Allergic (13) · Pulmonary Eosinophilia (8) · Respiratory Hypersensitivity (8) · Emergencies (7) · Asthma, Exercise-Induced (5) · Respiratory Sounds (5) · Lymphoma, Follicular (4) · Motor Activity (4) · Airway Remodeling (3) · Pneumonia (3) · Sinusitis (3) · Status Asthmaticus (3) · Asthma, Aspirin-Induced (2)
Hypersensitivity, Immediate (313) · Bronchial Diseases (311) · Hypersensitivity (311) · Immune System Diseases (311) · Respiratory Tract Diseases (311) · Lung Diseases, Obstructive (308) · Lung Diseases (307) · Respiratory Hypersensitivity (305) · Pathological Conditions, Signs and Symptoms (41) · Pathologic Processes (30) · Disease Attributes (25) · Otorhinolaryngologic Diseases (20) · Nose Diseases (19) · Chronic Disease (18) · Infections (16)
montelukast (42) · Fluticasone (39) · Albuterol (36) · Budesonide (27) · Fluticasone-Salmeterol Drug Combination (27) · Omalizumab (19) · Salmeterol Xinafoate (15) · Beclomethasone (11) · Mometasone Furoate (9) · Formoterol Fumarate (8) · Ipratropium (8) · Budesonide, Formoterol Fumarate Drug Combination (7) · Prednisolone (7) · ciclesonide (7) · Duration of Therapy (6)
GlaxoSmithKline (47) · AstraZeneca (21) · Organon and Co (17) · University of Saskatchewan (11) · University of Dundee (10) · Centre of Chinese Medicine, Georgia (8) · Imperial College London (6) · Novartis (6) · Boehringer Ingelheim (5) · Medical University of Lodz (5) · Kecioren Education and Training Hospital (4) · Teva Branded Pharmaceutical Products R&D, Inc. (4) · University of Florida (4) · University of Texas Southwestern Medical Center (4) · Children's Hospital of Philadelphia (3)
United States (104) · Canada (41) · United Kingdom (40) · Germany (27) · Italy (19) · Spain (19) · Netherlands (18) · Belgium (15) · Denmark (15) · France (15) · Poland (14) · Sweden (12) · Argentina (8) · China (8) · Finland (8)
Don Cockcroft, MD (6) · Manana Tchaia, MD (6) · Merab Lomia, MD, PhD (6) · Brian Lipworth, MD (4) · Leslie Hendeles, PharmD (4) · Tamara Tchelidze, MD (4) · C H Razi, MD (3) · Donald W Cockcroft, MD (3) · Francine M. Ducharme, MD, MSc (3) · Iwona Stelmach, MD, PhD, Prof (3)
PMID 20167147, PMID 32298853, PMID 33369570, PMID 36472162, PMID 37347518, PMID 37536444, PMID 37952772, PMID 12045120, PMID 12612294, PMID 15922813, PMID 16597501, PMID 16687712, PMID 17046300, PMID 17075269, PMID 17507702, PMID 17610727, PMID 17629923, PMID 17766511, PMID 18583517, PMID 18990678, PMID 19127072, PMID 19134016, PMID 19164187, PMID 19291931, PMID 19467341, PMID 19496252, PMID 19557208, PMID 19632710, PMID 19663124, PMID 19696440, PMID 19804441, PMID 19910613, PMID 20298399, PMID 20429821, PMID 20509942, PMID 20595145, PMID 20622031, PMID 20801010, PMID 20802165, PMID 20851928, PMID 21037369, PMID 21240480, PMID 21410369, PMID 21435854, PMID 21586508, PMID 21636667, PMID 21799027, PMID 21890336, PMID 21933100, PMID 22077869
2019 (4), 2015 (3), 2014 (2), 2016 (2), 2017 (2), 2005 (1), 2018 (1), P50HL056385 (1), R01HL114899 (1), R18HL092862 (1), U01HL080450 (1)