10 completed, 2 recruiting, 1 unknown. 13 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 13 | Completed 10, Recruiting 2, Unknown 1 |
| Phase 2 | 3 | Completed 2, Recruiting 1 |
Follow Arteriovenous Malformations: new trials by email Literature Review of Arteriovenous Malformations trials Research Report on Arteriovenous Malformations
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Anti-angiogenic Therapy With IV Bevacizumab in Patients With Symptomatic Cerebral Arteriovenous Malformations Bevacizumab, Placebo - Cerebral AV Malformation | Phase 2 / Phase 3 | Recruiting | Fondation Ophtalmologique Adolphe de Rothschild | 54 | 2026-01-16 | 2026-01-22 |
| Effects of Topical Lidocaine and Benzocaine on Pain Level and Injection Satisfaction Lidocaine Spray: Each ml contained 10 mg lidocaine and ethanol. Applied to the local site to provide anesthesia, Benzocaine spray, Placebo group (control arm) - Pain, Satisfaction | Phase 3 | Completed | TC Erciyes University | 60 | 2024-04-01 | 2025-12-01 |
| Randomised Clinical Trial Comparing Drug-coated Balloon to Plain Balloon for All Peripheral AVF Stenosis Angioplasty of all peripheral AVF stenosis - Arteriovenous Fistula, Arteriovenous Fistula Stenosis | Phase 3 | Recruiting | Singapore General Hospital | 94 | 2024-01-04 | 2024-08-14 |
| A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery Sirolimus - Complication of Renal Dialysis, End Stage Renal Disease | Phase 3 | Completed | Vascular Therapies, Inc. | 136 | 2022-08-26 | 2026-10-06 |
| Trial to Evaluate the Sirolimus-Eluting Collagen Implant on AV Fistula Outcomes Sirolimus, AV Fistula Surgery, Sirolimus-eluting Collagen Implant (SeCI) - Complication of Renal Dialysis, End Stage Renal Disease | Phase 3 | Completed | Vascular Therapies, Inc. | 269 | 2015-11-01 | 2025-10-09 |
| A Study of Vonapanitase (PRT-201) Administered Immediately After Radiocephalic Arteriovenous Fistula(AVF) Creation in Patients With Chronic Kidney Disease (CKD) (PATENCY-2) Vonapanitase, Placebo - Chronic Kidney Disease | Phase 3 | Completed | Proteon Therapeutics | 696 | 2015-08-01 | 2019-08-13 |
| Study Comparing Lutonix AV Drug Coated Balloon vs Standard Balloon for Treatment of Dysfunctional AV Fistulae Lutonix DCB, Standard Balloon Angioplasty Catheter, Percutaneous Transluminal Angiography - Arteriovenous Fistula | Phase 3 | Completed | C. R. Bard | 285 | 2015-06-01 | 2020-05-06 |
| A Study of PRT-201 Administered Immediately After Radiocephalic Arteriovenous Fistula(AVF) Creation in Patients With Chronic Kidney Disease (CKD) (PATENCY-1) PRT-201, Placebo - Chronic Kidney Disease | Phase 3 | Completed | Proteon Therapeutics | 349 | 2014-07-01 | 2019-07-09 |
| Functional Magnetic Resonance Imagine(fMRI)Navigation in Intracranial Arteriovenous Malformation Surgery fMRI Navigation AVM resection, conventional resection - Intracranial Arteriovenous Malformations | Phase 3 | Unknown | Beijing Tiantan Hospital | 600 | 2013-01-01 | 2013-03-04 |
| A Multicenter, Open-label Study for E7040 in Japanese Subjects With Hypervascular Tumor and Subjects With Arteriovenous Malformation E7040 - Hypervascular Tumor and Arteriovenous Malformation | Phase 3 | Completed | Eisai Co., Ltd. | 28 | 2012-08-01 | 2016-02-22 |
| Safety and Efficacy Study of the Venous Window Needle Guide to Access Arteriovenous (AV)Fistulae Venous Window Needle Guide - End Stage Renal Disease, AV Fistula | Phase 2 / Phase 3 | Completed | Vital Access Corp. | 54 | 2011-12-01 | 2016-06-03 |
| A Randomized Trial of Unruptured Brain AVMs Interventional therapy, Medical management - Arteriovenous Malformations, Cerebral | Phase 3 | Completed | Columbia University | 226 | 2006-10-01 | 2015-06-04 |
| A Safety Study of AQUAVAN® (Fospropofol Disodium) Injection for Sedation During Minor Surgical Procedures. AQUAVAN® (fospropofol disodium) Injection - Procedural Sedation | Phase 2 / Phase 3 | Completed | Eisai Inc. | 123 | 2006-05-01 | 2012-06-20 |
Arteriovenous Fistula (9) · Intracranial Arteriovenous Malformations (3) · Kidney Failure, Chronic (3) · Renal Insufficiency, Chronic (3) · Bunion (1) · Dilatation, Pathologic (1) · Intracranial Hemorrhages (1) · Pain (1) · Personal Satisfaction (1) · Renal Insufficiency (1) · Stroke (1)
Cardiovascular Abnormalities (13) · Cardiovascular Diseases (13) · Congenital Abnormalities (13) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (13) · Vascular Diseases (13) · Vascular Malformations (13) · Pathological Conditions, Signs and Symptoms (10) · Fistula (9) · Pathological Conditions, Anatomical (9) · Vascular Fistula (9) · Pathologic Processes (6) · Chronic Disease (5) · Disease Attributes (5) · Female Urogenital Diseases (5)
Sirolimus (2) · cholesterol-binding protein (2) · Bevacizumab (1) · Injections (1) · Lidocaine (1) · Practice Management, Medical (1) · fospropofol (1)
Proteon Therapeutics (2) · Vascular Therapies, Inc. (2) · Beijing Tiantan Hospital (1) · C. R. Bard (1) · Columbia University (1) · Eisai Co., Ltd. (1) · Eisai Inc. (1) · Fondation Ophtalmologique Adolphe de Rothschild (1) · Singapore General Hospital (1) · TC Erciyes University (1) · Vital Access Corp. (1)
United States (8) · Canada (2) · France (2) · United Kingdom (2) · Australia (1) · Austria (1) · Brazil (1) · China (1) · Finland (1) · Germany (1) · Italy (1) · Japan (1) · Netherlands (1) · Singapore (1) · South Korea (1)
Sriram Iyer, MD (2) · Alan J. Moskowitz, MD (1) · Christian Stapf, MD (1) · Claudia S. Moy, PhD (1) · Eric Vicaut, MD (1) · J.P. Mohr, MS, MD (1) · James B Jones, MD, PharmD (1) · Mark Crawford, BA (1) · Michael Parides, PhD (1) · Scott Trerotola, MD (1) · Shin Maeda (1) · Shuo Wang, MD (1)
PMID 36567000, PMID 38825327, PMID 17962585, PMID 19953376, PMID 24268105, PMID 24833247, PMID 25341453, PMID 27367242, PMID 28878048, PMID 29547081, PMID 30042225, PMID 30683197, PMID 31379715, PMID 32562682, PMID 33482699
U01NS051483 (1), U01NS051566 (1)