5 recruiting, 2 not yet recruiting. 7 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Recruiting 5, Not yet recruiting 2 |
| Phase 2 | 3 | Not yet recruiting 2, Recruiting 1 |
Follow Alzheimer s Disease: new trials by email Literature Review of Alzheimer s Disease trials Research Report on Alzheimer s Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| LiO-AD: Lithium Orotate in Alzheimers Disease Feasibility, Biomarker Engagement, and Clinical Response Lithium orotate, Matched Placebo (Capsules) - Alzheimer s Disease | Phase 1 / Phase 2 | Not yet recruiting | Johns Hopkins University | 40 | 2026-12-01 | 2026-10-07 |
| PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI) 18F-PF974, 18F-florbetaben - Alzheimer s Disease, Mild Cognitive Impairment | Phase 1 | Recruiting | National Institute of Mental Health (NIMH) | 90 | 2026-11-04 | 2026-10-30 |
| An Open Label Dose Escalation Study of VY1706 in Participants With Early Alzheimer's Disease VY1706 Low dose, VY1706 Mid dose, VY1706 High Dose - Alzheimer s Disease | Phase 1 | Recruiting | Voyager Therapeutics | 18 | 2026-09-03 | 2026-10-29 |
| A Study of the Metabolic Reconstruction Oral Biologics (Gut-X-001) Medication in People With Alzheimer's Disease (ESCAPE-AD) Gut-X-001 + Placebo capsule, Gut-X-001, Placebo - Alzheimer s Disease | Phase 1 / Phase 2 | Not yet recruiting | Beijing Tiantan Hospital | 120 | 2026-08-01 | 2026-06-11 |
| Low-Dose Radiotherapy for Alzheimer's Disease Low Dose Radiation Therapy - Alzheimer Dementia, Dementia | Phase 1 / Phase 2 | Recruiting | Evan Thomas | 50 | 2026-07-15 | 2026-07-09 |
| SAD Study of CGB3002 in Healthy Participants CGB3002 0.08 mg/kg, CGB3002 0.4 mg/kg, CGB3002 1.2 mg/kg - Alzheimer s Disease | Phase 1 | Recruiting | ChainGen Biopharma Ltd | 46 | 2026-06-30 | 2026-07-08 |
| Alzheimer's Disease and Faecal Microbiota Transplantation -a Pilot Study Biological: Preprocessed thawed donor FMT - Alzheimer s Disease, Faecal Microbiota Transplantation (FMT) | Phase 1 | Recruiting | University Hospital of North Norway | 10 | 2026-05-01 | 2026-04-22 |
Alzheimer Disease (2) · Dementia (2) · Cognitive Dysfunction (1)
Mental Disorders (3) · Neurocognitive Disorders (3) · Brain Diseases (2) · Central Nervous System Diseases (2) · Nervous System Diseases (2) · Neurodegenerative Diseases (2) · Tauopathies (2) · Cognition Disorders (1)
4-(N-methylamino)-4'-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)stilbene (1) · Biological Assay (1) · Capsules (1) · Radiotherapy (1) · lithium orotate (1)
Beijing Tiantan Hospital (1) · ChainGen Biopharma Ltd (1) · Evan Thomas (1) · Johns Hopkins University (1) · National Institute of Mental Health (NIMH) (1) · University Hospital of North Norway (1) · Voyager Therapeutics (1)
United States (3) · Australia (1) · Norway (1)
Christopher Morrow, MD, MHS (1) · Evan Thomas, MD, PhD (1) · Mona Dixon Gundersen, MBChB, PhD (1) · Paul A Parcon, M.D. (1) · Zhizheng Zhang, M.D. (1)