11 completed. 11 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 11 | Completed 11 |
| Phase 2 | 2 | Completed 2 |
Follow Adrenal Insufficiency: new trials by email Literature Review of Adrenal Insufficiency trials Research Report on Adrenal Insufficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation Thiotepa--single daily dose, Thiotepa--escalated dose - Bone Marrow Failure Syndrome, Thalassemia | Phase 1 / Phase 2 | Completed | University of Florida | 6 | 2018-06-15 | 2023-09-15 |
| A Study of Infacort® Versus Cortef® in Healthy Adult Male and Female Subjects Infacort®, Cortef® - Adrenal Insufficiency | Phase 1 | Completed | Neurocrine UK Limited | 51 | 2018-04-16 | 2026-09-14 |
| A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of OP-101 After Intravenous Administration in Healthy Volunteers OP-101 - Healthy | Phase 1 | Completed | Orpheris, Inc. | 8 | 2018-03-30 | 2018-09-17 |
| A Study of Chronocort® Versus Cortef ® in Healthy Adult Male Subjects Chronocort®, Cortef® - Adrenal Insufficiency | Phase 1 | Completed | Neurocrine UK Limited | 25 | 2018-02-19 | 2026-09-14 |
| Bioavailability of Infacort When Administered Onto Food Compared to Direct Oral Administration Infacort - Adrenal Insufficiency | Phase 1 | Completed | Neurocrine UK Limited | 19 | 2017-05-22 | 2026-09-14 |
| A Pilot Study of Vitamin D in Boys With X-linked Adrenoleukodystrophy vitamin D3 - X-linked Adrenoleukodystrophy | Phase 1 | Completed | Stanford University | 21 | 2016-11-21 | 2022-06-09 |
| Ultradian Subcutaneous Hydrocortisone Infusion in Addison Disease and Congenital Adrenal Hyperplasia Solu-Cortef, Cortef - Addison Disease, Adrenal Hyperplasia Congenital | Phase 1 / Phase 2 | Completed | Haukeland University Hospital | 8 | 2014-03-27 | 2024-06-07 |
| An Investigational Study of Hydrocortisone Hydrocortisone granules, Hydrocortisone Tablet, i.v. Hydrocortisone Injection - Adrenal Insufficiency | Phase 1 | Completed | Neurocrine UK Limited | 14 | 2013-10-01 | 2026-10-02 |
| Human Placental-Derived Stem Cell Transplantation Human Placental Derived Stem Cell - Mucopolysaccharidosis I, Mucopolysaccharidosis VI | Phase 1 | Completed | New York Medical College | 43 | 2013-04-01 | 2022-10-25 |
| A Two-part, Study to Compare the Pharmacokinetics and Dose Proportionality of up to 6 Chronocort Formulations Chronocort - Adrenal Insufficiency, Congenital Adrenal Hyperplasia | Phase 1 | Completed | Neurocrine UK Limited | 28 | 2011-02-01 | 2026-09-14 |
| An Open Label Study in Healthy Volunteers to Compare Chronocort® to Hydrocortisone Hydrocortisone, Chronocort - Congenital Adrenal Hyperplasia, Adrenal Insufficiency | Phase 1 | Completed | Neurocrine UK Limited | 30 | 2010-03-01 | 2026-09-14 |
Adrenoleukodystrophy (4) · Adrenal Hyperplasia, Congenital (3) · Anemia, Diamond-Blackfan (2) · Mucopolysaccharidosis I (2) · Addison Disease (1) · Anemia, Aplastic (1) · Anemia, Hemolytic (1) · Anemia, Sickle Cell (1) · Bone Marrow Failure Disorders (1) · Common Variable Immunodeficiency (1) · Demyelinating Diseases (1) · Fucosidosis (1) · Gaucher Disease (1) · Granulomatous Disease, Chronic (1)
Adrenal Gland Diseases (11) · Endocrine System Diseases (11) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (7) · Genetic Diseases, Inborn (7) · Metabolic Diseases (7) · Nutritional and Metabolic Diseases (7) · Metabolism, Inborn Errors (6) · Brain Diseases (4) · Brain Diseases, Metabolic (4) · Brain Diseases, Metabolic, Inborn (4) · Central Nervous System Diseases (4) · Genetic Diseases, X-Linked (4) · Hereditary Central Nervous System Demyelinating Diseases (4) · Heredodegenerative Disorders, Nervous System (4)
Hydrocortisone (5) · Cholecalciferol (1) · Dexamethasone (1) · Vitamin D (1) · hydrocortisone hemisuccinate (1)
Neurocrine UK Limited (6) · Haukeland University Hospital (1) · New York Medical College (1) · Orpheris, Inc. (1) · Stanford University (1) · University of Florida (1)
United Kingdom (4) · United States (4) · Norway (1)
A Koch (2) · Girish Sharma (2) · Biljana Horn, MD (1) · Katerina Simunkova, MD, PhD (1) · Keith Van Haren, MD (1) · Mitchell S Cairo, MD (1) · Salvatore Febbraro (1) · Stephen Huhn, MD (1)
K23NS087151 (1)