8 completed, 1 unknown. 9 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 9 | Completed 8, Unknown 1 |
Follow Adrenal Cortex Diseases: new trials by email Literature Review of Adrenal Cortex Diseases trials Research Report on Adrenal Cortex Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Adjuvant Chemotherapy vs. Observation/Mitotane After Primary Surgical Resection of Localized Adrenocortical CarcInoma Cisplatin plus Etoposide, Observation or Mitotane - Adrenocortical Carcinoma | Phase 3 | Completed | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | 40 | 2018-07-20 | 2024-08-01 |
| SPARTACUS: Subtyping Primary Aldosteronism: a Randomized Trial Comparing Adrenal Vein Sampling and Computed Tomography Scan. Ct-scan or adrenal vein sampling - Hyperaldosteronism | Phase 3 | Completed | Radboud University Medical Center | 200 | 2010-07-01 | 2015-07-16 |
| A Study of OSI-906 in Patients With Locally Advanced or Metastatic Adrenocortical Carcinoma OSI-906, Placebo - Adrenocortical Carcinoma | Phase 3 | Completed | Astellas Pharma Inc | 139 | 2009-12-01 | 2024-11-20 |
| An Extension Study of CORLUX in the Treatment of Endogenous Cushing's Syndrome mifepristone - Cushing's Syndrome | Phase 3 | Completed | Corcept Therapeutics | 30 | 2009-07-01 | 2014-04-02 |
| Efficacy of Adjuvant Mitotane Treatment (ADIUVO) MITOTANE - Adrenocortical Carcinoma | Phase 3 | Unknown | University of Turin, Italy | 200 | 2008-04-01 | 2017-05-08 |
| A Study of the Efficacy and Safety of CORLUX in the Treatment of Endogenous Cushing's Syndrome mifepristone - Cushing's Syndrome | Phase 3 | Completed | Corcept Therapeutics | 50 | 2007-12-01 | 2013-08-22 |
| Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Fentanyl sublingual spray, Placebo - Cancer | Phase 3 | Completed | INSYS Therapeutics Inc | 130 | 2007-10-01 | 2014-03-05 |
| Cisplatin-Based Chemotherapy and/or Surgery in Treating Young Patients With Adrenocortical Tumor Cisplatin, Conventional Surgery, Doxorubicin Hydrochloride - Stage I Adrenal Cortical Carcinoma AJCC v7, Stage II Adrenal Cortical Carcinoma AJCC v7 | Phase 3 | Completed | Children's Oncology Group | 78 | 2007-05-03 | 2024-02-28 |
| Trial in Locally Advanced and Metastatic Adrenocortical Carcinoma Treatment (FIRM-ACT) Etoposide, Doxorubicin, Cisplatin - Carcinoma, Adrenal Cortical | Phase 3 | Completed | Collaborative Group for Adrenocortical Carcinoma Treatment | 304 | 2004-06-01 | 2016-09-21 |
Adrenocortical Carcinoma (6) · ACTH Syndrome, Ectopic (2) · Adrenal Cortex Neoplasms (2) · Choristoma (2) · Cushing Syndrome (2) · Hirsutism (2) · Pituitary ACTH Hypersecretion (2) · Pituitary Diseases (2) · Adrenocortical Adenoma (1) · Anus Neoplasms (1) · Appendiceal Neoplasms (1) · Astrocytoma (1) · Bile Duct Neoplasms (1) · Blast Crisis (1) · Brain Neoplasms (1)
Adrenal Gland Diseases (9) · Adrenal Gland Neoplasms (9) · Endocrine Gland Neoplasms (9) · Endocrine System Diseases (9) · Neoplasms by Site (9) · Neoplasms (8) · Adrenal Cortex Neoplasms (7) · Adenocarcinoma (6) · Carcinoma (6) · Neoplasms by Histologic Type (6) · Neoplasms, Glandular and Epithelial (6) · Adrenocortical Hyperfunction (3) · Brain Diseases (3) · Central Nervous System Diseases (3)
Mitotane (4) · Cisplatin (3) · Etoposide (3) · Corlux (2) · Doxorubicin (2) · Mifepristone (2) · 1,2-diaminocyclohexaneplatinum II citrate (1) · 3-(8-amino-1-(2-phenylquinolin-7-yl)imidazo(1,5-a)pyrazin-3-yl)-1-methylcyclobutanol (1) · Chemotherapy, Adjuvant (1) · Dichlorodiphenyldichloroethane (1) · Ethane (1) · Fentanyl (1) · Filgrastim (1) · Granulocyte Colony-Stimulating Factor (1) · Observation (1)
Corcept Therapeutics (2) · Astellas Pharma Inc (1) · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (1) · Children's Oncology Group (1) · Collaborative Group for Adrenocortical Carcinoma Treatment (1) · INSYS Therapeutics Inc (1) · Radboud University Medical Center (1) · University of Turin, Italy (1)
United States (7) · Italy (4) · Netherlands (4) · Australia (3) · Canada (3) · France (3) · Germany (3) · United Kingdom (2) · Austria (1) · Brazil (1) · Poland (1) · Sweden (1)
Alfredo Berruti, MD (2) · Martin Fassnacht, MD (2) · Britt Skogseid, MD (1) · Carlos Rodriguez-Galindo (1) · Coleman Gross (1) · Coleman Gross, MD (1) · Eric Baudin, MD (1) · Harm Haak, MD (1) · Jacob Deinum, Dr. (1) · Larry Dillaha, MD (1) · Massimo Terzolo, MD (1)
PMID 22551107, PMID 25013998, PMID 26507877, PMID 11762335, PMID 15867769, PMID 16680602, PMID 17554118, PMID 18506026, PMID 19494162, PMID 19851811, PMID 20580485, PMID 21470991, PMID 22466348, PMID 22480131, PMID 22997446, PMID 23150683, PMID 23704714, PMID 23970019, PMID 23970725, PMID 25559399, PMID 25795408, PMID 27020837, PMID 27325147, PMID 29099925, PMID 34675114, PMID 37619579, PMID 9716042, PMID 9827725
2009 (1), U10CA098543 (1), U10CA180886 (1)