8 completed, 6 recruiting, 2 active not recruiting, 2 not yet recruiting. 4 Not applicable, 3 Phase 2, 2 Phase 3, 2 Phase 4, 1 Phase 1.
Follow Acute Kidney Injury (AKI): new trials by email Literature Review of Acute Kidney Injury (AKI) trials Research Report on Acute Kidney Injury (AKI)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Precision-Medicine Diagnostic Support in Hospitalized Veterans With Acute Kidney Injury PRECISE-AKI Clinical Decision Support Tool - Acute Kidney Injury (AKI) | Not applicable | Not yet recruiting | VA Office of Research and Development | 60 | 2028-01-01 | 2025-10-16 |
| COordiNated CommuNication, Education, and Care Transitions After Acute Kidney Injury (CONNECT-AKI) AKI Discharge Summary Template, Chat-Based Educational Messaging Program - Acute Kidney Injury, Acute Kidney Injury (AKI) | Not applicable | Recruiting | Northwell Health | 160 | 2026-06-24 | 2026-10-20 |
| The Impact of Blood Pressure Variability During the Induction and Surgical Periods on Postoperative Acute Kidney Injury Acute Kidney Injury (AKI) | Active not recruiting | Zhongda Hospital | 5000 | 2026-06-01 | 2026-09-10 | |
| Trimethoprim-Sulfamethoxazole (TMP/SMX) Prophylaxis After Acute Kidney Injury to Prevent Post-discharge Infections Drug: Trimethoprim-Sulfamethoxazole (TMP/SMX) 160/800 mg tablets every 48 hours, Placebo - Acute Kidney Injuries, Acute Kidney Disease | Phase 2 | Not yet recruiting | Hospital Civil de Guadalajara | 120 | 2025-12-01 | 2025-11-05 |
| Hamburg Acute Kidney Injury Study (HAKIS) Acute Kidney Injury, Acute Kidney Injury (AKI) | Recruiting | Universitätsklinikum Hamburg-Eppendorf | 1000 | 2025-09-16 | 2026-10-01 | |
| AST-120 (Kremezin®) for the Renal Protection and Attenuation of Decline in Acute Kidney Disease AST-120 (Kremezin®) - Acute Kidney Disease, Acute Kidney Injury (AKI) | Phase 4 | Recruiting | Chang Gung Memorial Hospital | 100 | 2025-09-15 | 2025-09-19 |
| NIRS Monitoring in the NICU and AKI NIRS Monitoring - Acute Kidney Injury (AKI), Postnatal AKI | Not applicable | Recruiting | NYU Langone Health | 100 | 2025-06-24 | 2026-10-22 |
| Occurrence of Acute Kidney Injury After CAR-T Cells Treatments in B-cell Lymphoma. Incidence of acute kidney injury, Describe risk factors in AKI occurrence., Focus on patient with chronic kidney disease at baseline - Acute Kidney Injury (AKI), Infusion of CD19 CAR T Cell | Active not recruiting | Hospices Civils de Lyon | 300 | 2025-04-01 | 2025-08-03 | |
| The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery Norepinephrine, Phenylephrine - Anesthesia, Surgery With General Anesthesia | Phase 4 | Recruiting | University of California, San Francisco | 18000 | 2025-04-01 | 2026-05-26 |
| Retrospective Analysis of Prismaflex HF20 Set Versus ppCRRT Registry Prismaflex HF20 - Acute Renal Failure (ARF), Acute Kidney Injury (AKI) | Completed | Vantive Health LLC | 59 | 2024-12-11 | 2026-02-17 | |
| Safety Evaluation of Prismocitrate 18 in Patients Receiving CRRT Prismocitrate 18, PrisMax System Version 3.x with calcium line accessory - Regional Citrate Anticoagulation (RCA), Continuous Renal Replacement Therapy (CRRT) | Phase 3 | Recruiting | Vantive Health LLC | 40 | 2024-07-12 | 2026-10-05 |
| Impact of Comprehensive Rehabilitation Nursing Combined With Refined Airway Management and Nutritional Support on Prognosis and Care Delivery Models in Critically Ill Patients Standard Critical Care Nursing Protocol, ICU-PRO Nursing Protocol (Integrated Critical Care Protocol for Rehabilitation Outcomes) - Critically Ill Patients, Nutritional Support | Not applicable | Completed | Taizhou Hospital of Traditional Chinese Medicine | 101 | 2023-06-02 | 2025-06-18 |
| Mitochondrial Health and Hemodynamic Instability Related to Renal Replacement Therapy in Critically Ill Patients Acute Kidney Injury (AKI) | Unknown | Ottawa Hospital Research Institute | 60 | 2021-12-06 | 2022-09-29 | |
| Effect of Cardiovascular Autonomic Neuropathy on AKI and Outcomes in Isolated CABG Surgery Acute Kidney Injury (AKI), Coronary Artery Bypass Graft (CABG) | Completed | Akdeniz University | 912 | 2021-11-04 | 2026-04-13 | |
| A Study to Evaluate RMC-035 in Subjects Undergoing Cardiac Surgery RMC-035, Placebo - Acute Kidney Injury (AKI) | Phase 1 | Completed | Guard Therapeutics AB | 13 | 2021-03-16 | 2024-04-23 |
| Observational Study to Evaluate the Epidemiology of Surgical-induced Acute Kidney Injury Acute Kidney Injury (AKI) | Completed | University Hospital Muenster | 10568 | 2020-06-09 | 2022-07-21 | |
| Study to Evaluate the Efficacy of ASP1128 (MA-0217) in Subjects at Risk for Acute Kidney Injury (AKI) Following Coronary Artery Bypass Graft (CABG) and/or Valve Surgery ASP1128, Placebo - Acute Kidney Injury (AKI) | Phase 2 | Completed | Astellas Pharma Inc | 351 | 2019-11-01 | 2024-12-04 |
| Acute Kidney Injury as a Risk Factor for Myocardial Injury After Non Cardiac Surgery Kidney function test - Acute Kidney Injury (AKI) | Completed | South Egypt Cancer Institute | 240 | 2019-03-01 | 2021-10-05 | |
| Fenoldopam to Prevent Renal Dysfunction in Indomethacin Treated Preterm Infants Fenoldopam, 0.9%NS - Patent Ductus Arteriosus (PDA), Acute Kidney Injury (AKI) | Phase 2 / Phase 3 | Terminated | Medical College of Wisconsin | 1 | 2019-02-06 | 2022-09-16 |
| Assessment of Plasma and NGAL for the Early Prediction of Acute Kidney Injury After Cardiac Surgery in Adults Study CPB Surgery - Acute Kidney Injury (AKI), Chronic Kidney Disease (CKD) | Completed | The Royal Wolverhampton Hospitals NHS Trust | 405 | 2016-05-01 | 2025-01-15 |
Acute Kidney Injury (20) · Ductus Arteriosus, Patent (1) · Gastrointestinal Hemorrhage (1) · Kidney Failure, Chronic (1) · Lymphoma, B-Cell (1) · Renal Insufficiency, Chronic (1) · Wounds and Injuries (1)
Female Urogenital Diseases (20) · Female Urogenital Diseases and Pregnancy Complications (20) · Kidney Diseases (20) · Male Urogenital Diseases (20) · Renal Insufficiency (20) · Urogenital Diseases (20) · Urologic Diseases (20) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Cardiovascular Abnormalities (1) · Cardiovascular Diseases (1) · Chronic Disease (1) · Congenital Abnormalities (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Digestive System Diseases (1)
ASP1128 (1) · AST 120 (1) · Fenoldopam (1) · Injections (1) · Kidney Function Tests (1) · Norepinephrine (1) · Phenylephrine (1) · Saline Solution (1) · Solutions (1) · Trimethoprim, Sulfamethoxazole Drug Combination (1)
Vantive Health LLC (2) · Akdeniz University (1) · Astellas Pharma Inc (1) · Chang Gung Memorial Hospital (1) · Guard Therapeutics AB (1) · Hospices Civils de Lyon (1) · Hospital Civil de Guadalajara (1) · Medical College of Wisconsin (1) · NYU Langone Health (1) · Northwell Health (1) · Ottawa Hospital Research Institute (1) · South Egypt Cancer Institute (1) · Taizhou Hospital of Traditional Chinese Medicine (1) · The Royal Wolverhampton Hospitals NHS Trust (1) · University Hospital Muenster (1)
United States (9) · Germany (3) · Canada (2) · China (2) · Egypt (2) · France (2) · Turkey (Türkiye) (2) · Italy (1) · Libya (1) · Malta (1) · North Macedonia (1) · Palestinian Territories (1) · Russia (1) · Saudi Arabia (1) · Slovenia (1)
Alexander Zarbock, MD, PhD (1) · Allison Janda, MD (1) · Douglas Colquhoun, MB ChB, MSc, MPH (1) · Edward D Siew, MD MSc (1) · Jeffrey Segar, MD (1) · Jia Hwei Ng, MD, MSCE (1) · Matthieu Legrand, MD PhD (1) · Michael E Matheny, MD MS MPH (1) · Michael P Bokoch, MD PhD (1) · Rousseau Gama (1) · Sachin Kheterpal, MD MBA (1) · Sourabh Verma, MD (1) · Tobias Agervald, MD PhD (1) · Tobias B Huber, MD (1)
PMID 35588372, PMID 37505258, PMID 38285051, PMID 39607014, PMID 41701325
K23DK132459 (1), R01DK139484 (1)