19 completed, 10 unknown, 6 recruiting, 1 active not recruiting. 25 Not applicable, 2 Phase 4, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 25 | Completed 15, Unknown 7, Recruiting 2, Active not recruiting 1 |
| Phase 4 | 2 | Recruiting 2 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Association of Inspiratory Effort With Dyspnea During Assisted Mechanical Ventilation in Critically Ill Patients Dyspnea During Mechanical Ventilation, Inspiratory Effort | Recruiting | University of Crete | 50 | 2026-06-18 | 2026-10-16 | |
| Physiotherapy After Emergency Laparotomy in the Elderly Experimental (Structured postoperative physiotherapy), Standard postoperative care - Emergency Abdominal Surgery | Not applicable | Recruiting | University of Cyprus | 250 | 2025-07-13 | 2026-03-31 |
| Effect of VExUS Ultrasound Protocol (Venous Excess Ultrasound) on Perioperative Fluid Management, on the Incidence of Postoperative Pulmonary Complications and Postoperative Acute Kidney Injury in Patients Undergoing Thoracic Surgery Venous Excess Ultrasound, Standard of Care (SOC) - Thoracic Surgery With One-lung Ventilation, VExUS | Not applicable | Recruiting | University of Crete | 230 | 2024-11-27 | 2025-12-02 |
| Prescribing Outcomes of a GP-Targeted Deprescribing Educational Intervention: A Cluster Randomized Trial Medication Reviews and Deprescribing - Medication Overuse, Deprescriptions | Not applicable | Active not recruiting | University of Crete | 200 | 2024-11-18 | 2026-02-09 |
| The Impact of Psychosocial Interventions in Patients with COPD Informational leaflet - Chronic Obstructive Pulmonary Disease (COPD) | Not applicable | Unknown | University of Crete | 160 | 2024-09-08 | 2024-09-19 |
| The Impact of Olive Oil Polyphenol Supplementation on Metabolic Syndrome Parameters: Preclinical Investigations Have Demonstrated That Olive Oil Polyphenols, Notably Oleocanthal, Oleacein, and Allied Secoiridoids, Possess Anti-inflammatory and Antioxidant Attributes Olive Oil Polyphenol Supplement (OOPs, OLEOPROTECT®, Thousand Olives®), Placebo capsules - Metabolic Syndrome | Not applicable | Completed | Apostolos Loukas Medical Centre Cyprus | 106 | 2024-09-01 | 2025-08-27 |
| FRESHAIR4Life: Building the Case for Action Tobacco Use, Pollution; Exposure | Unknown | Leiden University Medical Center | 1750 | 2023-10-01 | 2023-10-10 | |
| Investigating Diaphragm Thickness and Mobility in Healthy Parous and Nulliparous Volunteers Using RUSI Diagnostic Ultrasound Imaging of the diaphragm - Asymptomatic Condition | Completed | Evdokia Billis | 30 | 2023-06-01 | 2024-02-13 | |
| Emotion Regulation For All (ER4ALL) Study Emotion Regulation Course - Emotion Regulation | Not applicable | Unknown | University of Cyprus | 50 | 2023-03-01 | 2023-03-30 |
| Life Skills Boot Camp Study (LEVELUP2) Life Skills Boot Camp - Mental Health | Unknown | University of Cyprus | 120 | 2023-01-15 | 2023-03-31 | |
| Life Skills 101 Feasibility Study Psychoeducational - Soft Skills | Not applicable | Unknown | University of Cyprus | 120 | 2022-07-01 | 2022-09-02 |
| Electroacupuncture Pain Treatment, Mechanical Hyperalgesia, Quality of Life & Expression of Mu+ B Cells in Fibromyalgia Electroacupuncture, Nutrition, Dietary supplement - Fibromyalgia, Electroacupuncture | Recruiting | University of Crete | 80 | 2022-05-31 | 2022-10-26 | |
| Role of Epithelial Barrier Integrity in Biologic Treatment Response of Severe Asthmatics With/Out Chronic Rhinosinusitis With Nasal Polyps (CRSwNP). Mepolizumab 100 MG - Severe Eosinophilic Asthma w/wo CRSwNP | Unknown | University of Crete | 85 | 2022-05-15 | 2024-01-18 | |
| A Multimodal Intervention Program for Children With Attention Deficits (Child ViReal Support Program) Behavioral Parent Training (BPT), Child Training (iVR + CBT) - Attention Deficit, Attention Deficit Disorder With Hyperactivity | Not applicable | Completed | University of Crete | 16 | 2022-03-01 | 2023-11-29 |
| Ultrasound-guided Biofeedback for Transversus Abdominus Re-education in Non-specific Low Back Pain Patients Real-time rehabilitative ultrasound imaging (RUSI), Tactile feedback (control intervention) - Non-specific Low Back Pain (NSLBP) | Not applicable | Completed | University of Patras | 23 | 2022-01-15 | 2023-05-18 |
| PAP Adherence After Diet/Lifestyle Intervention in OSA Patients MDG intervention - Obstructive Sleep Apnea | Not applicable | Completed | University of Crete | 74 | 2021-12-01 | 2023-05-31 |
| Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLC Opioid-Based Anesthesia-Analgesia Strategy, Opioid-free Anesthesia-Analgesia Strategy - Systemic Inflammatory Response Syndrome, Postoperative Pain, Acute | Phase 4 | Recruiting | University of Crete | 70 | 2021-10-01 | 2021-12-29 |
| Metabolic Biomarkers in Hashimoto's Thyroiditis and Psoriasis Nutraceutical Combination Plan - Hashimoto Disease, Psoriasis | Not applicable | Unknown | University of Crete | 200 | 2021-02-02 | 2024-06-28 |
| Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm Repair Opioid-Based Anesthesia-Analgesia Strategy, Opioid-free Anesthesia-Analgesia Strategy - Elective Surgical Procedures, Postoperative Pain | Phase 4 | Recruiting | University of Crete | 40 | 2020-10-08 | 2026-06-16 |
| Assessment of the Clinical Effectiveness of a Herbal Extract (Cretan IAMA) in Patients With Viral Respiratory Infections, Including COVID-19, in Primary Healthcare Settings, and Co-assessment of Its Prophylactic Effect in People Cohabiting With These Patients Cretan IAMA - Covid19, Viral Infection | Phase 2 / Phase 3 | Completed | University of Crete | 20 | 2020-04-01 | 2021-01-12 |
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Sleep Apnea, Obstructive (5) · Pulmonary Disease, Chronic Obstructive (3) · Tobacco Use (3) · Chronic Pain (2) · Emotional Regulation (2) · Pain, Postoperative (2) · Psychological Well-Being (2) · Acute Kidney Injury (1) · Asymptomatic Diseases (1) · Atrial Fibrillation (1) · Attention Deficit Disorder with Hyperactivity (1) · COVID-19 (1) · Carcinoma, Non-Small-Cell Lung (1) · Color Vision Defects (1) · Communicable Diseases (1)
Continuous Positive Airway Pressure (2) · Positive-Pressure Respiration (2) · Standard of Care (2) · Angioplasty (1) · Critical Care (1) · Deprescriptions (1) · Dietary Supplements (1) · Electroacupuncture (1) · Intraocular Pressure (1) · Medication Review (1) · Methods (1) · Nutritional Status (1) · Self-Management (1) · Surveys and Questionnaires (1) · Tiotropium Bromide (1)
Greece (26) · Cyprus (7) · Netherlands (2) · Spain (2) · Belgium (1) · Israel (1)
Sophia E Schiza, MD, PhD (5) · Izolde Bouloukaki, MD, PhD (3) · Charalampos Mermigkis, MD (2) · Sophia Schiza, MD, PhD (2) · Alexandra Papaioannou, Professor of Anaesthesiology (1) · Antonia Aravantinou Karlatou, Social Worker MSc, PhDc (1) · Aristidis Tsatsakis, PhD, Prof (1) · Charalampos Mermigkis, MD, PhD (1) · Christos Lionis (1) · Christos Lionis, MD, PhD (1) · Constantine Vardavas, MD,RN,MPH,PHD (1) · Dimitrios Tsetis, MD, PhD (1) · Evangelos Karademas, Professor of Psychology (1) · Evdokia Billis (1) · Evdokia Billis, PhD (1)
PMID 12148093, PMID 20543206, PMID 21918812, PMID 22034645, PMID 23386371, PMID 24993911, PMID 25057935, PMID 25058504, PMID 25304302, PMID 25645191, PMID 26015461, PMID 26197368, PMID 28831208, PMID 28934952, PMID 30176976, PMID 30304509, PMID 32270297, PMID 33108270, PMID 33390932, PMID 33407248, PMID 34375444, PMID 35995638, PMID 36963790, PMID 37237315, PMID 38099161, PMID 38388489, PMID 41429309, PMID 41758830, PMID 9872255