23 recruiting, 12 active not recruiting, 12 completed, 4 not yet recruiting. 24 Phase 2, 16 Phase 1, 12 Not applicable, 4 Phase 3, 1 Early Phase 1.
Follow Photons: new trials by email Literature Review of Photons trials Research Report on Photons
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma Actinium Ac 225 Lintuzumab, Biospecimen Collection, Cemiplimab - Recurrent Glioblastoma, IDH-Wildtype, Recurrent Gliosarcoma | Phase 1 | Not yet recruiting | National Cancer Institute (NCI) | 30 | 2026-12-04 | 2026-06-12 |
| Pluvicto for the Treatment of African American Men With Metastatic Castration-Resistant Prostate Cancer Biopsy Procedure, Biospecimen Collection, Bone Scan - Metastatic Castration-Resistant Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 | Not yet recruiting | Emory University | 88 | 2026-11-02 | 2026-10-06 |
| Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have Spread to Bones Biospecimen Collection, Bone Scan, Computed Tomography - Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma | Phase 1 | Withdrawn | National Cancer Institute (NCI) | 2026-10-01 | 2026-08-28 | |
| Testing an Anti-cancer Radio-Active Immunotherapy Called Lintuzumab Ac225 in Patients With High-Risk Myelodysplastic Syndrome That Has Not Responded to Other Treatment Actinium Ac 225 Lintuzumab, Bone Marrow Aspiration, Buccal Swab - Refractory Myelodysplastic Syndrome | Phase 1 | Suspended | National Cancer Institute (NCI) | 18 | 2026-09-03 | 2026-09-09 |
| Study of PSMA-targeted Therapy and Androgen Receptor Suppression in Low-volume Metastatic ProstatE Cancer: SPARKLE Trial Abiraterone Acetate, Biospecimen Collection, Leuprolide Acetate - Recurrent Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 | Recruiting | Mayo Clinic | 202 | 2026-08-04 | 2026-09-18 |
| A Study of Ivonescimab in People With Non-Small Cell Lung Cancer Photon or Proton standard stereotactic body radiotherapy (SBRT), Ivonescimab - Non-Small Cell Lung Cancer | Phase 1 / Phase 2 | Recruiting | Memorial Sloan Kettering Cancer Center | 36 | 2026-05-12 | 2026-05-18 |
| Y-90 Radioembolization, Durvalumab, Tremelimumab, and Zanzalintinib for the Treatment of Unresectable and Locally-Advanced Hepatocellular Carcinoma Angiogram, Biopsy Procedure, Biospecimen Collection - Locally Advanced Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8 | Phase 2 | Not yet recruiting | OHSU Knight Cancer Institute | 40 | 2026-04-02 | 2026-04-06 |
| Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial Biospecimen Collection, Computed Tomography, Cystoscopy - Muscle Invasive Bladder Urothelial Carcinoma, Stage II Bladder Cancer AJCC v8 | Phase 2 | Recruiting | National Cancer Institute (NCI) | 111 | 2025-11-25 | 2026-10-01 |
| Personalized Neck Radiation Therapy Directed by Sentinel Lymph Node Biopsy for the Treatment of Oral Cavity Squamous Cell Carcinoma, PRECEDENT Trial Biospecimen Collection, Carboplatin, Cisplatin - Oral Cavity Squamous Cell Carcinoma, Stage I Lip and Oral Cavity Cancer AJCC v8 | Phase 2 | Recruiting | University of Michigan Rogel Cancer Center | 50 | 2025-07-17 | 2026-07-31 |
| 225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome Actinium Ac 225-DOTA-Daratumumab, Biospecimen Collection, Bone Marrow Aspiration - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Phase 1 | Recruiting | City of Hope Medical Center | 15 | 2025-07-01 | 2026-07-31 |
| Low PSMA SUV Boost (LPS-Boost): Intensified 177Lu-PSMA-617 Treatment for Patients With Metastatic Castrate-Resistant Prostate Cancer With Low PSMA Expressing Disease Biospecimen Collection, Bone Scan, Computed Tomography - Metastatic Castration-Resistant Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 | Recruiting | University of Washington | 51 | 2025-04-29 | 2026-07-07 |
| Radiation Therapy With RapidPlan Knowledge-based Planning vs Human-Driven Planning for Treatment of Prostate Cancer Biospecimen Collection, Magnetic Resonance Imaging, Photon Beam Radiation Therapy - Prostate Carcinoma | Phase 3 | Recruiting | Mayo Clinic | 108 | 2025-02-02 | 2026-10-02 |
| Yttrium-90 (Y90) Radioembolization for the Treatment of Early Stage Renal Cell Carcinoma, The RENEGADE Trial Angiogram, Biospecimen Collection, Computed Tomography - Stage I Renal Cell Cancer, Stage II Renal Cell Cancer | Phase 1 / Phase 2 | Recruiting | Jonsson Comprehensive Cancer Center | 25 | 2024-12-26 | 2026-08-21 |
| Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer Biopsy Procedure, Biospecimen Collection, Bone Scan - Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma | Phase 2 | Recruiting | Fred Hutchinson Cancer Center | 15 | 2024-09-18 | 2026-08-06 |
| Re-treatment With 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer, RE-LuPSMA Trial Biospecimen Collection, Computed Tomography, Gallium Ga 68 Gozetotide - Castration-Resistant Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 | Recruiting | Jonsson Comprehensive Cancer Center | 40 | 2024-08-01 | 2026-03-13 |
| Phase 2 Randomized Trial of Flexible Dosing Schedule of 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer (FLEX-MRT) Computed Tomography, Gallium Ga 68 Gozetotide, Lutetium Lu 177 Vipivotide Tetraxetan - Prostate Carcinoma, Stage IVB Prostate Cancer American Joint Committee on Cancer (AJCC) v8 | Phase 2 | Recruiting | Jonsson Comprehensive Cancer Center | 90 | 2024-08-01 | 2026-03-10 |
| Evaluation of Immune Responses and Outcomes in Patients With Hepatocellular Carcinoma Undergoing Radiotherapy Photon or proton radiotherapy - Hepatocellular Carcinoma | Recruiting | Chang Gung Memorial Hospital | 300 | 2024-05-23 | 2026-10-01 | |
| Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer Biospecimen Collection, Bone Scan, Clinical Observation - Castration-Resistant Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 | Suspended | Mayo Clinic | 236 | 2024-05-03 | 2026-08-20 |
| Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial Bevacizumab, Capecitabine, Cetuximab - Metastatic Colorectal Carcinoma, Metastatic Malignant Neoplasm in the Liver | Phase 3 | Recruiting | ECOG-ACRIN Cancer Research Group | 408 | 2024-04-10 | 2026-09-24 |
| Predicting Esophageal Cancer Borders Using PET-Imaging photon, surgical therapy, Chemotherapy - Esophagus Cancer, Stage I, Esophagus Cancer, Stage II | Phase 2 | Recruiting | University Hospital Heidelberg | 30 | 2024-03-01 | 2026-03-10 |
Showing 20 of 57. Sign in to see all of them.
Prostatic Neoplasms (14) · Carcinoma, Non-Small-Cell Lung (6) · Breast Neoplasms (5) · Carcinoma, Hepatocellular (5) · Glioblastoma (4) · Lung Neoplasms (4) · Myelodysplastic Syndromes (3) · Neoplasms (3) · Gliosarcoma (2) · Leukemia, Myeloid, Acute (2) · Liver Neoplasms (2) · Lymphoma, Large-Cell, Anaplastic (2) · Lymphoma, T-Cell (2) · Mouth Neoplasms (2) · Mycosis Fungoides (2)
Mayo Clinic (11) · National Cancer Institute (NCI) (6) · Jonsson Comprehensive Cancer Center (5) · University of Washington (4) · M.D. Anderson Cancer Center (3) · NRG Oncology (3) · Technische Universität Dresden (3) · University Hospital Heidelberg (3) · Abramson Cancer Center at Penn Medicine (2) · Emory University (2) · University of Florida (2) · Chang Gung Memorial Hospital (1) · City of Hope Medical Center (1) · ECOG-ACRIN Cancer Research Group (1) · Fred Hutchinson Cancer Center (1)
United States (45) · Germany (6) · Canada (3) · China (2) · Taiwan (1)
Armeen Mahvash (2) · Jeremie Calais, MD (2) · Jing Zeng (2) · Adel Kardosh (1) · Alexander Lin, MD (1) · Angela Castellanos Rodriguez, MD, MSc (1) · Bonnie Ky, MD (1) · Brian Shuch (1) · Chandan Guha, M.B.B.S., Ph.D. (1) · David M Schuster, MD, FACR (1) · Dusica Babovic-Vuksanovic, MD (1) · Fabio M Iwamoto (1) · Henning Willers, MD (1) · Jacob E Berchuck, MD (1)
PMID 35175355, PMID 31142507, PMID 31619413, PMID 32972877, PMID 33027064, PMID 33641042, PMID 34172602, PMID 36898933, PMID 37143154, PMID 38407630, PMID 38739047, PMID 38981590, PMID 40876952, PMID 41276366, PMID 41679923, PMID 42389925
U10CA180868 (3), P30CA016672 (2), P30CA138292 (2), P50CA186781 (2), R01CA262613 (2), 261201500022C-0-0-1 (1), P30CA015083 (1), P30CA015704 (1), P30CA033572 (1), P50CA127001 (1), R01CA204301 (1), R01HL157273 (1), R37CA286450 (1), U10CA180820 (1), U10CA180821 (1)