69 completed, 22 recruiting, 11 active not recruiting, 10 unknown. 83 Not applicable, 8 Phase 2, 5 Phase 1, 5 Phase 4, 2 Early Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The MIND Study: The MGH/MIT Investigation of NAC on Dysregulation N-Acetyl Cysteine (NAC), Placebo - Emotional Dysregulation | Early Phase 1 | Not yet recruiting | Massachusetts General Hospital | 120 | 2027-01-01 | 2026-04-17 |
| Gamma Light and Sound Stimulation in Schizophrenia GENUS, Sham Stimulation - Schizophrenia Spectrum Disorders | Not applicable | Not yet recruiting | Massachusetts Institute of Technology | 20 | 2026-12-01 | 2026-10-07 |
| Non-invasive Induction of Metaplasticity for Amblyopia Flicker - Amblyopia, Amblyopia Unilateral | Not applicable | Not yet recruiting | Boston Children's Hospital | 10 | 2026-11-01 | 2026-09-29 |
| Transcranial Ultrasonic Neuromodulation of Primary Visual Cortex and Primary Auditory Cortex in Humans Transcranial Focused Ultrasound Stimulation, Electroencephalography, Magnetic Resonance Imaging - Healthy Volunteers, no Condition, Basic Science | Not applicable | Not yet recruiting | Massachusetts Institute of Technology | 20 | 2026-10-01 | 2026-06-29 |
| Measurement of Ocular Microtremor With the iTremor Device in a Diverse US Cohort All Conditions, All | Enrolling by invitation | Head Diagnostics | 120 | 2026-09-28 | 2026-10-05 | |
| Non-Invasive Detection and Preservation of Neurocognitive Signals in the Peri-Death Period Using Brain-Computer Interface and Artificial Intelligence Terminal Illness, End-of-Life Care | Not yet recruiting | Noah Tech, Corp. | 20 | 2026-09-01 | 2026-03-17 | |
| Wearable Ultrasound Patch for Breast Imaging Wearable Ultrasound Patch - Breast Cancer, Breast Abnormalities | Not applicable | Not yet recruiting | Massachusetts General Hospital | 50 | 2026-09-01 | 2026-07-21 |
| Continuous Wireless Ultrasound to Monitor Fetal Health Wireless Ultrasound Device - Pregnant Woman With Single Pregnancy, Ultrasound Fetal Medicine | Recruiting | Boston Children's Hospital | 50 | 2026-09-01 | 2026-10-22 | |
| PRISM-NLM: Prostatectomy Intraoperative Surgical Margin Assessment With Non-linear Microscopy Nonlinear Microscope (NLM) - Prostate Cancer | Not applicable | Not yet recruiting | Beth Israel Deaconess Medical Center | 20 | 2026-06-01 | 2026-04-08 |
| Shortwave Infrared Surgical Imaging Device Study Observational study of SWIR imaging device in surgery - Cholecystitis, Cholecystitis, Chronic | Enrolling by invitation | Cision Vision, Inc. | 50 | 2026-05-29 | 2026-08-04 | |
| The TEAM Study - Treatment Efficacy for Autism/Attention Using Mixed Amphetamine Adderall XR (mixed salts amphetamine), Placebo - Attention Deficit Hyperactivity Disorder (ADHD), Autism | Phase 4 | Recruiting | Gagan Joshi | 196 | 2026-02-01 | 2026-03-06 |
| Resilience in Reentry: Cognitive-Behavioral Resilience Training for Parolees With Adjustment Challenges Cognitive Behavioral Therapy - Adjustment | Not applicable | Recruiting | University of California, Irvine | 60 | 2026-01-27 | 2026-10-08 |
| Study of Wearable Interventions for Improving Mobility of Individuals With Knee Osteoarthritis Dephy Exoboot - Knee Osteoarthristis | Not applicable | Recruiting | Massachusetts Institute of Technology | 9 | 2025-12-15 | 2026-06-17 |
| Investigating the Effects of Social Stress on Brain Imaging Trier Social Stress Test (TSST) - Social Stress | Not applicable | Active not recruiting | Massachusetts Institute of Technology | 50 | 2025-11-17 | 2026-08-11 |
| Evaluation of a Powered Ankle Prosthesis Capable of Bidirectional Control Via Neural Recording and Cutaneous Stimulation in Free-Space and Walking Tasks Powered Prosthesis, Prescribed Prosthesis - Amputation | Not applicable | Recruiting | Massachusetts Institute of Technology | 10 | 2025-10-21 | 2026-06-12 |
| Investigating the Effects of Cannabidiol on Social Anxiety Disorder Cannabidiol, Placebo - Phobia, Social | Phase 4 | Recruiting | Massachusetts Institute of Technology | 50 | 2025-07-10 | 2026-08-11 |
| Haptic Feedback for Improved Interoceptive Awareness and Mental Well-being Heart rate feedback from smartwatch - Interoceptive Awareness, Interoception | Not applicable | Completed | Massachusetts Institute of Technology | 29 | 2025-06-26 | 2026-09-09 |
| Circadian-informed Optimal Bedtime Optimal Bedtime, Placebo - Sleep, Alertness, Fatigue, Mood, and Performance | Not applicable | Completed | Massachusetts Institute of Technology | 203 | 2025-06-11 | 2026-10-23 |
| Evaluation of a Neural-Controlled Powered Prosthesis Across Diverse Real-World Tasks MIT Powered Leg - Transfemoral Amputation | Not applicable | Recruiting | Massachusetts Institute of Technology | 10 | 2025-05-31 | 2025-10-02 |
| Evaluation of Suvorexant for Reduction of Brain Reactivity in Patients With Cannabis Use Disorder (Pilot Study) Suvorexant - Cue-reactivity, Cannabis Use Disorder | Phase 4 | Completed | Massachusetts General Hospital | 20 | 2025-03-10 | 2026-07-01 |
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Christopher F Chabris, PhD (6) · John Gabrieli, PhD (5) · Li-Huei Tsai, PhD (5) · Matthew J Carty, MD (4) · Amy Finkelstein, PhD (3) · Hugh Herr, PhD (3) · Hugh M Herr, PhD (3) · Joseph Biederman, MD (3) · Michelle N Meyer, PhD JD (3) · Diane Chan, MD, PhD (2) · Edward S Boyden, PhD (2) · Joseph Doyle, PhD (2) · Aamir J. Khan, MD/PhD. (1) · Abhijit Banerjee, PhD (1) · Alan C Moss, MD PhD (1)
PMID 36454969, PMID 33593940, PMID 42834081, PMID 15531489, PMID 15972272, PMID 16076944, PMID 19675988, PMID 25835472, PMID 26740683, PMID 26975533, PMID 27802283, PMID 27807037, PMID 27929004, PMID 28439720, PMID 28877894, PMID 29284461, PMID 30609986, PMID 31328671, PMID 31837266, PMID 31914242, PMID 32587364, PMID 33347320, PMID 34413518, PMID 34963501, PMID 34963502, PMID 35273490, PMID 35858717, PMID 36206005, PMID 37055459, PMID 37126719, PMID 37632535, PMID 37698862, PMID 37811711, PMID 37930792, PMID 38011750, PMID 38633772, PMID 38641090, PMID 39012630, PMID 39024366, PMID 39701335, PMID 40117132, PMID 41137616, PMID 41396271, PMID 41538765, PMID 42090155, PMID 42640640
P30AG034532 (4), K23DC016656 (1), P01AG005842 (1), P30AG064190 (1), P50MH119467 (1), R01CA243454 (1), R01CA249151 (1), R01DA034699 (1), R01EB017337 (1), R01EB024531 (1), R01HD097135 (1), R01MH128377 (1), R21CA106745 (1), R21DK071674 (1), R34HL125859 (1)