22 completed. 22 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 22 | Completed 22 |
Follow Cross Research S.A.: new trials by email
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Palatability Study of Five Formulations of Benzydamine HCl Lozenges benzydamine HCl - Healthy Volunteers, Palatability | Phase 1 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 120 | 2025-04-13 | 2025-09-30 |
| Study to Evaluate the Safety and Concentrations of Monoclonal Antibody Against Virus That Causes COVID-19 Disease. MAD0004J08, Placebo - COVID-19 Virus Disease | Phase 1 | Completed | Toscana Life Sciences Sviluppo s.r.l. | 30 | 2021-03-01 | 2022-04-27 |
| Riluzole Orodispersible Film Replicate Bioavailability Riluzole 50 mg orodispersible film, Rilutek® 50 mg riluzole tablets - Healthy Participants | Phase 1 | Completed | Cross Research S.A. | 54 | 2021-01-15 | 2025-05-02 |
| Bioavailability Study of 300 mg Trazodone Hydrochloride (New Polymer) vs. 300 mg Trazodone Hydrochloride (Contramid® Prolonged-release Tablets) Under Fasting Conditions Trazodone HCl - new polymer, Trazodone HCl - Contramid® - Healthy | Phase 1 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 28 | 2020-02-17 | 2021-11-29 |
| Bioequivalence of Ketoprofen Oral Gel vs Ketoprofen Lysine Salt as Granules for Oral Solution Ketoprofen Lysine, Ketoprofen Oral Product - Healthy | Phase 1 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 36 | 2018-07-23 | 2020-12-21 |
| Bioequivalence of Flurbiprofen Lozenge vs Strepfen Flurbiprofen Test 8.75 MG, Flurbiprofen Reference 8.75 MG - Healthy | Phase 1 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 24 | 2018-06-19 | 2020-12-17 |
| A Novel Mouthwash Formulation CTP/BNZ With Mucus Adhesive Polymer Cetylpyridinium Chloride 0.05% + Benzydamine HCl 0.15% + mucus adhesive polymer, Cetylpyridinium Chloride 0.05% + Benzydamine HCl 0.15% - Healthy | Phase 1 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 26 | 2017-11-14 | 2020-08-05 |
| Safinamide Steady State Interaction With Rosuvastatin 100 mg safinamide, 20 mg rosuvastatin calcium period 1, 20 mg rosuvastatin calcium period 2 - Healthy | Phase 1 | Completed | Cross Research S.A. | 24 | 2017-05-22 | 2017-08-01 |
| Effects of Three Single Oral Doses of Trazodone on the QTc Interval Duration in Healthy Volunteers Trazodone 20 mg, Trazodone 60 mg, Trazodone 140 mg - Healthy | Phase 1 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 20 | 2017-03-20 | 2020-07-31 |
| Crossover, Single Dose, Two-stage Bioequivalence Study of SCMC-Lys Salt 1.35 g Powder vs SCMC-Lys Salt 90 mg/mL Syrup SCMC-lys powder 1.35 g, Fluifort® syrup - Bronchitis | Phase 1 | Completed | Dompé Farmaceutici S.p.A | 30 | 2016-07-04 | 2024-11-18 |
| Bioequivalence Study of Ibuprofen 200 mg/5 mL Oral Suspension vs. MOMENT 200 mg Coated Tablet Ibuprofen 200 mg/5 mL oral suspension, MOMENT 200 mg coated tablet - Healthy | Phase 1 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 60 | 2016-06-01 | 2016-09-15 |
| Bioequivalence Study of Ibuprofen 400 mg/10 mL Oral Suspension vs. MOMENTACT 400 mg Film-coated Tablet Ibuprofen 400 mg/10 mL oral suspension, MOMENT 400 mg coated tablet - Healthy | Phase 1 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 60 | 2016-05-01 | 2016-09-15 |
| Bioequivalence Study of One Tablet of Paracetamol 1000 mg + Codeine 30 mg vs. Two Tablets of Paracetamol 500 mg + Codeine 30 mg Paracetamol 1000 mg/codeine phosphate hemihydrate 30 mg tablet, Paracetamol 500 mg/codeine phosphate hemihydrate 30 mg tablet - Healthy | Phase 1 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 46 | 2016-04-01 | 2016-09-16 |
| Tolerability and Pharmacokinetic Study of Econazole Nitrate Plus Benzydamine HCl Vaginal Pessary Econazole nitrate 150 mg plus Benzydamine HCl 6 mg vaginal pessary, Placebo plus Econazole nitrate 150 mg vaginal pessary, Placebo plus Benzydamine HCl 6 mg vaginal pessary - Healthy Women | Phase 1 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 49 | 2016-03-04 | 2017-02-07 |
| Study to Assess the Effect of Multiple Doses of Tradipitant on CYP3A4 Using Midazolam as a Substrate in Healthy Subjects tradipitant, Midazolam - Healthy Volunteers | Phase 1 | Completed | Vanda Pharmaceuticals | 24 | 2015-11-01 | 2016-04-27 |
| Tolerability and Pharmacokinetic Study of Econazole Nitrate and Benzydamine HCl Intravaginal Cream Econazole nitrate 1% plus Benzydamine HCl 0.12% intravaginal cream, Placebo plus Econazole nitrate 1% intravaginal cream, Placebo plus Benzydamine HCl 0.12% intravaginal cream - Healthy | Phase 1 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 48 | 2015-09-01 | 2018-01-17 |
| Drug Interaction Study of Safinamide and a BCRP Substrate, Diclofenac, Concomitantly Administered to Healthy Volunteers Diclofenac sodium, Diclofenac sodium and safinamide - Healthy | Phase 1 | Completed | Zambon SpA | 24 | 2015-05-01 | 2016-04-15 |
| Ibuprofen (MOMENT ACT ANALGESIC Granules) Pharmacokinetic Study Ibuprofen - Healthy | Phase 1 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 24 | 2015-02-01 | 2015-06-26 |
| Crossover, Single Dose Randomized, Bioequivalence of Ketoprofen Lysine Salt Immediate Release vs Oral Solution KSL 40 mg, OKi® 80 mg - Pain Disorders | Phase 1 | Completed | Dompé Farmaceutici S.p.A | 30 | 2014-11-26 | 2024-04-19 |
| Safety Tolerability & Pharmacokinetics of Co-administered Single Doses of OZ439 & Piperaquine to Healthy Subjects 100mg OZ439 single oral dose, Placebo, 300 mg OZ439 single oral dose - Healthy | Phase 1 | Completed | Medicines for Malaria Venture | 59 | 2012-09-01 | 2015-01-21 |
Showing 20 of 22. Sign in to see all of them.
Anthrax (1) · Bronchitis (1) · COVID-19 (1) · Dysmenorrhea (1) · Headache (1) · Leukemia, Hairy Cell (1) · Neuralgia (1) · Somatoform Disorders (1) · Toothache (1)
Benzydamine (4) · Ibuprofen (3) · Econazole (2) · Suspensions (2) · Trazodone (2) · safinamide (2) · Acetaminophen (1) · Cetylpyridinium (1) · Diclofenac (1) · Filgrastim (1) · MAD0004J08 (1) · Metered Dose Inhalers (1) · Midazolam (1) · Moxifloxacin (1) · Powders (1)
Switzerland (20) · Italy (1)
Milko Radicioni, MD (14) · Andrea Paolini (1) · Antonio Rusca, MD (1) · Antonio Rusca, MD, FMH (1) · Milko M Radicioni, MD PhD (1) · Milko Radicioni (1)
PMID 21615456, PMID 24555723, PMID 32410819, PMID 32488885, PMID 34473343, PMID 35477725