14 completed, 2 terminated, 1 active not recruiting, 1 unknown. 5 Phase 1, 4 Not applicable, 3 Phase 4, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 4, Unknown 1 |
| Not applicable | 4 | Completed 3, Terminated 1 |
| Phase 4 | 3 | Completed 3 |
| Phase 2 | 2 | Completed 2 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of the Treatment and Outcomes in Critically Ill Patients With COVID-19 No intervention - Coronavirus Infection | Completed | Brigham and Women's Hospital | 5154 | 2020-04-01 | 2023-08-09 | |
| Problem Solving Training for Care Partners of Adults With Traumatic Brain Injury Problem Solving Training (PST), Education - Care Partners of Patients With Traumatic Brain Injury (TBI) | Not applicable | Completed | University of Texas Southwestern Medical Center | 94 | 2018-11-20 | 2025-03-05 |
| A Culturally Targeted Transplant Program Hispanic Kidney Transplant Program (HKTP) - ESRD | Not applicable | Completed | Northwestern University | 11836 | 2017-01-18 | 2026-07-02 |
| A Prospective Observational Study of TPIAT TPIAT - Pancreatitis, Chronic, Pancreatectomy; Hyperglycemia | Active not recruiting | University of Minnesota | 433 | 2017-01-01 | 2026-04-09 | |
| Evaluation of Early Standardized Task-Specific Training (ESTT) Early standardized task training - Acute Stroke | Not applicable | Terminated | University of Texas Southwestern Medical Center | 12 | 2012-08-01 | 2015-10-01 |
| Phase I/II Adaptive Randomized Trial of Bevacizumab Versus Bevacizumab Plus Vorinostat in Adults With Recurrent Glioblastoma vorinostat, bevacizumab - Malignant Glioma, Recurrent Glioblastoma | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 96 | 2011-07-12 | 2018-07-31 |
| A Retrospective Analysis of Neevo® and NeevoDHA® Compared to a Standard Prenatal Vitamin in Anemia During Pregnancy Neevo®, Prenatal vitamins - Anemia in Pregnancy, Pre-eclampsia | Terminated | Pamlab, L.L.C. | 30 | 2010-07-01 | 2011-11-23 | |
| A Retrospective Analysis of Neevo®/Neevo®DHA Compared to a Standard Prenatal Vitamin in Anemia During Pregnancy Neevo® (a medical food), Prenatal vitamins (≤1mg folic acid, 27 - 35mg iron, and ≤12mcg vitamin B12) - Anemia in Pregnancy, Preeclampsia | Completed | Pamlab, Inc. | 100 | 2009-12-01 | 2013-04-16 | |
| Combination Deplin® and Antidepressant Therapy for a Major Depressive Episode (MDE)- a Retrospective Analysis L-methylfolate, Selective serotonin reuptake inhibitor (SSRI), Serotonin and norepinephrine reuptake inhibitor (SNRI) - Major Depressive Disorder | Completed | Pamlab, Inc. | 242 | 2009-08-01 | 2013-12-19 | |
| Recombinant Human Growth Hormone During Rehabilitation From Traumatic Brain Injury. Recombinant human Growth Hormone, Placebo - Traumatic Brain Injury | Phase 2 | Completed | University of Pennsylvania | 63 | 2008-09-01 | 2019-11-18 |
| Pancreatic Islet Cell Transplantation - A Novel Approach to Improve Islet Quality and Engraftment Islet cell transplantation - Islet Cell Transplantation, Type 1 Diabetes | Phase 1 | Completed | Baylor Research Institute | 1 | 2008-07-01 | 2017-04-24 |
| Breathing Training for Asthma Capnometry Assisted Respiration Training, Breathing Awareness - ASTHMA | Not applicable | Completed | Southern Methodist University | 120 | 2008-07-01 | 2018-06-04 |
| Study of Metanx® in Subjects With Type 2 Diabetic Peripheral Neuropathy (DPN) Metanx (a medical food), Metanx placebo - Type 2 Diabetic Peripheral Neuropathy (DPN) | Phase 4 | Completed | Pamlab, Inc. | 214 | 2008-06-01 | 2013-08-30 |
| Project to Improve Symptoms and Mood in People With Spinal Cord Injury venlafaxine XR, placebo - Major Depressive Disorder, Dysthymia | Phase 4 | Completed | University of Washington | 133 | 2007-07-01 | 2015-01-01 |
| Pancreatic Islet Cell Transplantation Islet cell transplantation - Type 1 Diabetes | Phase 1 | Completed | Baylor Research Institute | 4 | 2005-04-01 | 2017-06-14 |
| Study of Liver Transplant For End-Stage Liver Disease Caused By Chronic Hepatitis C Infection Daclizumub, Tacrolimus, Cyclosporine - End Stage Liver Disease, Hepatitis C | Phase 4 | Completed | Baylor Research Institute | 312 | 2002-07-01 | 2017-01-12 |
| Vaccine Therapy in Treating Patients With Metastatic Melanoma filgrastim, therapeutic autologous dendritic cells - Melanoma (Skin) | Phase 1 | Unknown | Baylor Health Care System | 2001-04-01 | 2013-09-17 | |
| Vaccine Therapy in Treating Patients With Metastatic Melanoma MART-1 antigen, filgrastim, flu matrix peptide p58-66 - Melanoma (Skin) | Phase 1 | Completed | Baylor Health Care System | 1999-04-01 | 2013-06-26 |
Diabetes Mellitus (3) · Hyperglycemia (3) · Depressive Disorder, Major (2) · Diabetes Mellitus, Type 1 (2) · Hypoglycemia (2) · Iron Deficiencies (2) · Melanoma (2) · Pre-Eclampsia (2) · Airway Obstruction (1) · Anxiety Disorders (1) · Asthma (1) · Brain Injuries, Traumatic (1) · Cognitive Dysfunction (1) · Coronavirus Infections (1) · Depression (1)
Filgrastim (2) · Islets of Langerhans Transplantation (2) · Prenatal Care (2) · 5-methyltetrahydrofolate (1) · Bevacizumab (1) · Cyclosporine (1) · Daclizumab (1) · Educational Status (1) · Folic Acid (1) · Growth Hormone (1) · Iron (1) · MAGEA3 protein, human (1) · MART-1 Antigen (1) · Mycophenolic Acid (1) · Selective Serotonin Reuptake Inhibitors (1)
United States (18)
Joseph W. Fay, MD (2) · Alicia Meuret, PhD (1) · Charles H. Bombardier, PhD (1) · David E Leaf, MD, MMSc (1) · Elisa J Gordon, PhD (1) · Goran Klintmalm, MD (1) · Jesse R. Fann, MD, MPH (1) · Juan Carlos J Caicedo, MD (1) · Karen J McCain, PT, DPT, NCS (1) · Lawrence D Ginsberg, MD (1) · Mark Millard, MD (1) · Mark R Gilbert, M.D. (1) · Marlon Levy, MD (1) · Nicholas Onaca, MD (1) · Nicole Jarvis, M.D. (1)
PMID 21440300, PMID 21255766, PMID 21311704, PMID 22440484, PMID 23218892, PMID 25122497, PMID 25607727, PMID 25613597, PMID 30885800, PMID 31034642, PMID 32282660, PMID 32609874, PMID 32667668, PMID 32844546, PMID 32961244, PMID 32998872, PMID 33026829, PMID 33037746, PMID 33067383, PMID 33080002, PMID 33493012, PMID 33528595, PMID 33591017, PMID 33595960, PMID 33872546, PMID 33891529, PMID 33964301, PMID 34109768, PMID 34337554, PMID 34476402, PMID 34559944, PMID 34786562, PMID 34871701, PMID 34918709, PMID 34939474, PMID 35524363, PMID 35584148, PMID 35659156, PMID 36050992, PMID 36193749, PMID 36961348, PMID 37379286
R01DK109124 (1), R01HL089761 (1)