16 completed, 3 recruiting, 2 terminated, 2 unknown. 24 Phase 3, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 24 | Completed 16, Recruiting 3, Terminated 2, Unknown 2, Not yet recruiting 1 |
| Phase 2 | 5 | Completed 4, Unknown 1 |
Follow Venlafaxine: new trials by email Literature Review of Venlafaxine trials Research Report on Venlafaxine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An Artificial Intelligence Driven Approach to Optimize Patient Selection for a Transitional Pain Service TPS-Select, Pharmacologic Pain Management, Interventional Pain Procedures - Postsurgical Pain Management, Postsurgical Pain, Chronic | Phase 3 | Not yet recruiting | University of California, San Francisco | 474 | 2026-10-01 | 2026-10-09 |
| Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure Clozapine, Esketamine Nasal Product, Escitalopram - Schizophrenia and Related Disorders, Major Depressive Disorder | Phase 3 | Recruiting | Dr. Inge Winter | 1254 | 2025-04-27 | 2026-01-22 |
| The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. Escitalopram, Sertraline, Venlafaxine - Bipolar Depression | Phase 3 | Recruiting | Dr. Inge Winter | 418 | 2025-02-11 | 2025-09-26 |
| REDucing Hot FLASHes in Women Using Endocrine Therapy. Oxybutynin, Venlafaxine - Breast Cancer, Hot Flash Due to Medication | Phase 3 | Recruiting | Reinier de Graaf Groep | 260 | 2024-10-03 | 2025-02-04 |
| Vortioxetine as a Novel Anti-depressant With Improvement in Cognitive Abilities Vortioxetine, Venlafaxine - Major Depressive Disorder | Phase 3 | Unknown | Scotmann Pharmaceuticals | 500 | 2022-02-01 | 2021-11-18 |
| The Potential Protective Role of Venlafaxine Versus Memantine in Paclitaxel Induced Peripheral Neuropathy Venlafaxine, Memantine - Oncology Pain, Chemotherapy-induced Peripheral Neuropathy | Phase 2 / Phase 3 | Unknown | Mendel AI | 60 | 2021-02-15 | 2021-02-04 |
| Assessing the Efficacy of a Serotonin and Norepinephrine Reuptake Inhibitor for Improving Meniere's Disease Outcomes Venlafaxine, Placebo oral tablet - Meniere Disease | Phase 2 / Phase 3 | Completed | Medical University of South Carolina | 40 | 2020-02-05 | 2024-07-23 |
| Pharmacovigilance in Gerontopsychiatric Patients Phenobarbital, Phenytoin, Carbamazepine - Dementia, Depression | Phase 3 | Terminated | Hannover Medical School | 407 | 2015-01-01 | 2018-02-28 |
| Trazodone Once a Day in Major Depression Disorder Trazodone, Venlafaxine - Major Depressive Disorder | Phase 3 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 364 | 2012-12-01 | 2015-12-30 |
| Estimate the Efficiency of the Association of an Injection of Ketamine and the Venlafaxine in the Severe Major Depressive Disorder for Six Weeks ketamine venlafaxine, Venlafaxine - Major Depressive Disorder | Phase 3 | Completed | University Hospital, Grenoble | 25 | 2012-03-01 | 2017-02-24 |
| Antidepressants and Bone Mineral Density sertraline, citalopram, venlafaxine - Bone Mineral Density Quantitative Trait Locus 7 | Phase 3 | Completed | Guiyang Medical University | 203 | 2012-03-01 | 2014-07-01 |
| A Study of Eszopiclone Co-administered With Venlafaxine in Subjects With Major Depressive Disorder and Insomnia Eszopiclone, Placebo, Venlafaxine - Major Depressive Disorder, Insomnia | Phase 3 | Completed | Sumitomo Pharma America, Inc. | 678 | 2007-06-01 | 2012-02-22 |
| Soy Protein/Effexor Hormone Therapy for Prostate Cancer oral soy protein/isoflavones powder, Venlafaxine, Placebo Powder - Hot Flashes, Prostate Cancer | Phase 3 | Terminated | Wake Forest University Health Sciences | 120 | 2007-02-01 | 2021-09-28 |
| Efficacy of Seroquel SR in Combination With an Antidepressant in Treatment of Major Depressive Disorder Quetiapine, Amitriptyline, Bupropion - Major Depressive Disorder | Phase 3 | Completed | AstraZeneca | 494 | 2006-05-01 | 2011-01-26 |
| Study of Antidepressants in Parkinson's Disease paroxetine, venlafaxine, placebo - Parkinson Disease, Depression | Phase 3 | Completed | University of Rochester | 115 | 2005-06-01 | 2013-01-04 |
| A Comparison of Duloxetine Hydrochloride, Marketed Comparator, and Placebo in the Treatment of Generalized Anxiety Disorder Duloxetine, venlafaxine, placebo - Anxiety Disorder | Phase 3 | Completed | Eli Lilly and Company | 560 | 2005-04-01 | 2007-10-18 |
| Study Comparing Venlafaxine vs. Paroxetine in Panic Disorder VENLAFAXINE, Paroxetine - Panic Disorders | Phase 3 | Completed | Wyeth is now a wholly owned subsidiary of Pfizer | 70 | 2005-01-01 | 2010-04-02 |
| A Comparison of Duloxetine Hydrochloride, Marketed Comparator, and Placebo in the Treatment of Generalized Anxiety Disorder Duloxetine, venlafaxine, placebo - Anxiety Disorders | Phase 3 | Completed | Eli Lilly and Company | 480 | 2004-10-01 | 2007-11-06 |
| Treatment of Hot Flushes Caused by Leuprorelin 11.25 mg in Prostate Adenocarcinoma Cyproterone acetate, Medroxyprogesterone acetate, Venlafaxine - Adenocarcinoma, Prostate | Phase 3 | Completed | Takeda | 311 | 2004-04-01 | 2015-07-30 |
| Treatment of Adolescent Suicide Attempters (TASA) fluoxetine, sertraline, citalopram - Depression, Suicide, Attempted | Phase 2 / Phase 3 | Completed | New York State Psychiatric Institute | 120 | 2004-03-01 | 2020-06-22 |
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Depressive Disorder, Major (7) · Depression (6) · Anxiety Disorders (4) · Bipolar Disorder (2) · Hot Flashes (2) · Schizophrenia (2) · Adenocarcinoma (1) · Alcohol-Related Disorders (1) · Alcoholism (1) · Breast Neoplasms (1) · Cancer Pain (1) · Dementia (1) · Depressive Disorder (1) · Dysthymic Disorder (1) · Meniere Disease (1)
Dr. Inge Winter (2) · Eli Lilly and Company (2) · Alliance for Clinical Trials in Oncology (1) · AstraZeneca (1) · Aziende Chimiche Riunite Angelini Francesco S.p.A (1) · Boston Medical Center (1) · Guiyang Medical University (1) · Hannover Medical School (1) · Medical University of South Carolina (1) · Mendel AI (1) · New York State Psychiatric Institute (1) · Reinier de Graaf Groep (1) · Scotmann Pharmaceuticals (1) · Sumitomo Pharma America, Inc. (1) · Takeda (1)
United States (10) · France (4) · Austria (3) · Canada (3) · Germany (3) · Romania (3) · United Kingdom (3) · Australia (2) · Belgium (2) · Czechia (2) · Italy (2) · Poland (2) · Russia (2) · Spain (2) · Argentina (1)
Andrew Bishara, MD (1) · Charles L. Loprinzi, MD (1) · David A. Brent, MD (1) · Domenic Ciraulo, MD (1) · Filippo Bogetto, MD (1) · Habib Rizk, MD (1) · Helge Frieling, Prof., MD (1) · Irene Richard, MD (1) · Jacques Barber, PhD (1) · Laurence Greenhill, MD (1) · Lemonitsa Mammatas, PhD (1) · Mara Vitolins, DrPH, RD (1)
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2023 (1), R01AA013727 (1), R01MH061410 (1), U01MH061835 (1), U10CA081851 (1), U10MH066750 (1), U10MH066762 (1), U10MH066769 (1), U10MH066775 (1), U10MH066778 (1)