5 completed, 2 recruiting, 2 unknown, 1 withdrawn. 10 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 5, Recruiting 2, Unknown 2, Withdrawn 1 |
| Phase 1 | 1 | Completed 1 |
Follow Tocopherols: new trials by email Literature Review of Tocopherols trials Research Report on Tocopherols
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Reversing External-beam Radiotherapy-associated Fibrosis Syndrome: an Interventional Bayesian Adaptive Randomized-controlled Orphan Drug Platform Trial for Orodental Sequelae (Reverse-fibrose) Pravastatin (drug), Pentoxifylline, ketoprofen - Fibrosis Syndrome, Lymphedema | Phase 2 | Recruiting | M.D. Anderson Cancer Center | 250 | 2025-08-08 | 2026-07-24 |
| Systemic Therapy of Open-label Prophylactic Pravastatin or Pentoxifylline/Tocopherol Prevention of Lymphedema Advancing to Eventual Fibrosis: an Interventional Registry-embedded Bayesian Randomized Trial for Radiation Sequelae (STOP4-LATE-FIBROSE) Pravastatin, Pentoxifylline, Tocopherol - Lymphedema, Fibrosis | Phase 2 | Recruiting | M.D. Anderson Cancer Center | 295 | 2025-02-13 | 2026-09-11 |
| Comparison of Effectiveness of Obeticholic Acid With Vitamin E in Patients of Non-alcoholic Fatty Liver Disease Obeticholic Acid 10 MG, Vitamin E 400mg - Non Alcoholic Fatty Liver Disease | Phase 2 | Completed | King Edward Medical University | 90 | 2023-08-24 | 2025-08-05 |
| Treatment of Radiation-induced Fibrosis in the Upper Aerodigestive Tract Cancer by a Combination of Pentoxifylline-tocopherol and Hyperbaric Oxygen pentoxifylline with tocopherol, pentoxifylline+tocopherol + Hyperbaric Oxygen Therapy - Fibrosis | Phase 2 | Unknown | Hospital Universitario de Canarias | 42 | 2010-07-01 | 2013-04-02 |
| Effect of Vitamin E Supplementation on Hemoglobin Levels in Healthy Adults Vitamin E, placebo (edible oil) - Anemia | Phase 1 / Phase 2 | Completed | Aga Khan University | 357 | 2008-11-01 | 2014-07-03 |
| How Does Manual Therapy Improve Low Back Pain for Soldiers? Soft Tissue, Myofascial release, Counterstrain - Low Back Pain | Phase 2 | Unknown | University of North Texas Health Science Center | 100 | 2006-10-01 | 2006-10-31 |
| Provision of Antioxidant Therapy in Hemodialysis (PATH) Study Alpha, gamma, beta, and delta (mixed) tocopherols, Alpha lipoic acid, Placebo - End-stage Renal Disease | Phase 2 | Completed | Vanderbilt University | 385 | 2006-04-01 | 2012-01-11 |
| Tocopherols and Alpha Lipoic Acid Treatment Chronic Kidney Disease (TALAT) Alpha, gamma, beta, and delta (mixed) tocopherols, alpha lipoic acid, placebo - Chronic Kidney Disease | Phase 2 | Completed | Vanderbilt University | 62 | 2006-03-01 | 2009-07-09 |
| Tocopherol is a Novel Treatment for Cancer Related Mucositis Tocopherol - Oral Mucositis | Phase 2 | Withdrawn | Hadassah Medical Organization | 30 | 2005-12-01 | 2011-04-08 |
| 13-Cis Retinoic Acid With or Without Vitamin E for Prevention of Lung Cancer 13-cis retinoic acid, Tocopherol - Drug Toxicity, Lung Cancer | Phase 2 | Completed | University of Colorado, Denver | 96 | 1993-01-01 | 2020-05-15 |
Fibrosis (3) · Lymphedema (2) · Anemia (1) · Carcinoma, Non-Small-Cell Lung (1) · Drug-Related Side Effects and Adverse Reactions (1) · Head and Neck Neoplasms (1) · Kidney Failure, Chronic (1) · Low Back Pain (1) · Lung Neoplasms (1) · Non-alcoholic Fatty Liver Disease (1) · Renal Insufficiency, Chronic (1) · Small Cell Lung Carcinoma (1) · Stomatitis (1)
M.D. Anderson Cancer Center (2) · Vanderbilt University (2) · Aga Khan University (1) · Hadassah Medical Organization (1) · Hospital Universitario de Canarias (1) · King Edward Medical University (1) · University of Colorado, Denver (1) · University of North Texas Health Science Center (1)
United States (6) · Pakistan (2) · Israel (1) · Spain (1)
Alp Ikizler, MD (2) · Jonathan Himmelfarb, MD (2) · Clifton Fuller, MD (1) · Clifton Fuller, MD,PHD (1) · Douglas M Maurer, D.O. (1) · Dr. Tanveer Jilani, MBBS, M.Phil (1) · Scott T Stoll, D.O., Ph.D. (1) · Shimon Slavin, MD (1) · Tazeen Nazar, MBBS,FCPSMed (1) · York E. Miller, MD (1)