7 completed, 5 terminated, 3 unknown, 1 recruiting. 16 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 16 | Completed 7, Terminated 5, Unknown 3, Recruiting 1 |
| Phase 2 | 4 | Completed 2, Terminated 1, Unknown 1 |
Follow Thiamine: new trials by email Literature Review of Thiamine trials Research Report on Thiamine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| COLchicine and Thiamine in Heart Failure Due to Ischemic Heart Disease Colchicine 0.5 MG, Colchicine placebo, Thiamine Mononitrate 300 mg - Heart Failure | Phase 3 | Recruiting | Hamilton Health Sciences Corporation | 2500 | 2024-01-29 | 2026-10-02 |
| the Effect of Vitamin B 1 on Menstrual Pattern After Insertion of the IUD. VITAMIN B1 500mg, intra-uterine contraceptive device - Intra-uterine Device Complication | Phase 3 | Unknown | Beni-Suef University | 200 | 2023-07-30 | 2023-08-02 |
| Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Vitamin C, Placebo - Sepsis, Septic Shock | Phase 3 | Terminated | Hospital Sirio-Libanes | 71 | 2021-08-01 | 2024-01-30 |
| Effect of IV Vitamin C, Thiamine, and Steroids on Mortality of Septic Shock Vitamin C, Normal saline - Septic Shock | Phase 3 | Terminated | New York Presbyterian Brooklyn Methodist Hospital | 3 | 2019-10-15 | 2020-02-10 |
| Effect of Thiamin Supplementation on Thiamin Status in Children With Heart Disease Receiving Diuretic Drugs Thiamine Mononitrate - Heart Diseases | Phase 3 | Unknown | Mahidol University | 60 | 2019-07-01 | 2019-06-20 |
| Vitamin C, Thiamine and Hydrocortisone for the Treatment of Septic Shock Vitamin C,thiamine,hydrocortisone, Placebo - Septic Shock | Phase 3 | Completed | Northern Jiangsu People's Hospital | 408 | 2019-02-19 | 2021-09-23 |
| Vitamin C, Thiamine, and Steroids in Sepsis Vitamin C, Thiamine, Hydrocortisone - Sepsis | Phase 3 | Completed | Emory University | 501 | 2018-08-22 | 2021-04-13 |
| Evaluation of Hydrocortisone, Vitamin C and Thiamine for the Treatment of Septic Shock Triple therapy group - Septic Shock, Critical Illness | Phase 2 / Phase 3 | Terminated | Hamad Medical Corporation | 106 | 2018-03-17 | 2021-12-10 |
| Ascorbic Acid, Corticosteroids, and Thiamine in Sepsis (ACTS) Trial vitamin C, vitamin B1, hydrocortisone, Normal saline - Sepsis, Septic Shock | Phase 2 / Phase 3 | Completed | Beth Israel Deaconess Medical Center | 205 | 2018-02-09 | 2021-02-16 |
| Thiamine Supplementation in Heart Failure Patients Receiving Full Medical Therapy Thiamine - Chronic Heart Failure | Phase 3 | Completed | Mashhad University of Medical Sciences | 50 | 2010-05-01 | 2010-12-23 |
| Does Thiamine Help Vomiting and Nausea in Pregnancy? thiamine & promethazine - Hyperemesis Gravidarum | Phase 3 | Terminated | HaEmek Medical Center, Israel | 50 | 2009-02-01 | 2015-06-23 |
| Steroids in Patients With Early ARDS Methylprednisolone, Normal saline intravenously and vitamin B1 per os - Acute Lung Injury, ARDS, Human | Phase 2 / Phase 3 | Unknown | Catholic University of the Sacred Heart | 400 | 2008-02-01 | 2007-11-22 |
| Neuropathic Pain Management F0434, Gabapentin - Diabetic Neuropathies, Polyneuropathies | Phase 3 | Completed | Merck KGaA, Darmstadt, Germany | 104 | 2008-02-01 | 2014-02-13 |
| Effectiveness of Dalteparin Therapy as Intervention in Recurrent Pregnancy Loss Fragmin P Forte (dalteparin sodium), Multivitamin supplement - Abortion, Habitual | Phase 3 | Completed | University of Jena | 449 | 2006-11-01 | 2014-09-17 |
| Impact Of Antioxidant Micronutrients On Intensive Care Unit (ICU) Outcome Selenium (Se), Zinc (Zn), Vitamin C, Vitamin B1, Vitamin E, Placebo - Critically Ill Patients, Cardiac Surgery | Phase 3 | Terminated | Centre Hospitalier Universitaire Vaudois | 200 | 2003-01-01 | 2010-07-30 |
| D4T or Abacavir Plus Vitamin Enhancement in HIV-Infected Patients (DAVE) d4T, Abacavir, Riboflavin and Thiamine (Supplementation) - Acidosis, Lactic | Phase 2 / Phase 3 | Completed | University of British Columbia | 80 | 2001-08-01 | 2008-09-25 |
Shock, Septic (5) · Sepsis (3) · Critical Illness (2) · Heart Failure (2) · Abortion, Habitual (1) · Acidosis, Lactic (1) · Acute Lung Injury (1) · Beriberi (1) · Diabetes Mellitus (1) · Diabetic Neuropathies (1) · Heart Diseases (1) · Hyperemesis Gravidarum (1) · Nausea (1) · Polyneuropathies (1) · Respiratory Distress Syndrome (1)
Beni-Suef University (1) · Beth Israel Deaconess Medical Center (1) · Catholic University of the Sacred Heart (1) · Centre Hospitalier Universitaire Vaudois (1) · Emory University (1) · HaEmek Medical Center, Israel (1) · Hamad Medical Corporation (1) · Hamilton Health Sciences Corporation (1) · Hospital Sirio-Libanes (1) · Mahidol University (1) · Mashhad University of Medical Sciences (1) · Merck KGaA, Darmstadt, Germany (1) · New York Presbyterian Brooklyn Methodist Hospital (1) · Northern Jiangsu People's Hospital (1) · University of British Columbia (1)
United States (3) · Canada (2) · Austria (1) · Brazil (1) · China (1) · Egypt (1) · Germany (1) · Iran (1) · Israel (1) · Italy (1) · Mexico (1) · Qatar (1) · Switzerland (1) · Thailand (1)
Adham Mohamed, PharmD (1) · Ekkehard Schleussner, Prof. Dr. (1) · Gisele Queiroz, MD (1) · Jonathan Sevransky, MD, MHS (1) · Julio Montaner, MD (1) · Liam Gross, DO (1) · Luciano CP Azevedo, PhD (1) · Massimo Antonelli, MD (1) · Mehdi Mousavi, Cardiologist (1) · Mette M Berger, MD PhD (1) · Michael W Donnino, MD (1) · Mohamed Abdelaty, MD (1) · Narumon Densupsoontorn, MD (1) · Philip G Joseph, M.D. (1)
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