7 completed, 5 unknown, 2 withdrawn, 1 recruiting. 10 Not applicable, 3 Phase 2, 1 Phase 1, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Unknown 5, Completed 3, Suspended 1, Withdrawn 1 |
| Phase 2 | 3 | Completed 2, Withdrawn 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
| Phase 4 | 1 | Recruiting 1 |
Follow Supplemental Oxygen: new trials by email Literature Review of Supplemental Oxygen trials Research Report on Supplemental Oxygen
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of Nocturnal Hypoxemia on Glucose in High Altitude Sleep Disordered Breathing Compressed Air, Supplemental Oxygen - Sleep-Disordered Breathing, Glucose Intolerance | Not applicable | Withdrawn | Johns Hopkins University | 2025-12-01 | 2026-01-07 | |
| Coca-Cola vs. Oxygen for Fatigue Management in Tibet Surgeons Coca-Cola, Supplemental oxygen - Fatigue | Not applicable | Unknown | Peking Union Medical College Hospital | 22 | 2024-09-01 | 2024-08-16 |
| Is Obstructive Sleep Apnea Important in the Development of Alzheimer's Disease? Supplemental Oxygen, Continuous Positive Airway Pressure Machine, Room Air - OSA, Sleep Apnea | Phase 1 | Completed | University of California, San Diego | 182 | 2021-10-08 | 2026-05-11 |
| Do Endotypes Predict Response and Sequelae in OSA Patients Eszopiclone, Supplemental Oxygen, Continuous Positive Airway Pressure (CPAP) - Obstructive Sleep Apnea, Sleep Apnea | Phase 2 | Completed | University of California, San Diego | 233 | 2020-08-01 | 2026-06-18 |
| Non-Invasive Positive Pressure Ventilation Management of High Altitude Pulmonary Edema Non-Invasive Positive Pressure Ventilation, Nifedipine, supplemental oxygen - High Altitude Pulmonary Edema, Non-Invasive Positive Pressure Ventilation | Not applicable | Unknown | Massachusetts General Hospital | 16 | 2020-03-01 | 2020-09-03 |
| SuperNO2VA™ and General Anesthesia Postoperative Care SuperNO2VA nasal positive airway pressure devic, Supplemental oxygen - Hypoxemia, Acute Respiratory Failure | Not applicable | Unknown | Vyaire Medical | 150 | 2018-10-15 | 2019-06-03 |
| Obstructive Sleep Apnea and Glucose Metabolism Positive Airway Pressure, Supplemental Oxygen, Sham - Sleep Apnea, Glucose Metabolism Disorders | Not applicable | Suspended | University of Missouri-Columbia | 80 | 2018-01-17 | 2026-05-08 |
| Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury Acute episodic hypoxia, Supplemental oxygen, Trazodone - Sleep Apnea, Spinal Cord Injury | Phase 4 | Recruiting | John D. Dingell VA Medical Center | 100 | 2017-06-09 | 2026-07-01 |
| Efficacy and Physiology of Nasal High Flow Therapy NHF therapy, Long term Oxygen Therapy (LOT) - Pulmonary Disease, Chronic Obstructive | Not applicable | Completed | Institut für Pneumologie Hagen Ambrock eV | 46 | 2014-04-01 | 2019-02-11 |
| Abciximab (ReoPro) as a Therapeutic Intervention for Sickle Cell Vaso-Occlusive Pain Crisis Abciximab, Placebo, Intravenous hydration - Sickle Cell Disease, Hb-SS Disease With Vasoocclusive Pain | Phase 2 | Withdrawn | St. Louis University | 2013-11-01 | 2015-03-26 | |
| Comparison of Two Techniques of Sciatic Nerve Block With Levobupivacaine 0.5% in Orthopedic Surgery Sciatic nerve anesthesia blockade at bifurcation., Sciatic nerve blockade 2 cm beyond the bifurcation, Levobupivacaine 0.5%: 20 ml - Anesthesia | Not applicable | Unknown | CES University | 66 | 2013-04-01 | 2013-04-19 |
| Estimating Apnea Phenotypes From Polysomnography: Oxygen Inspired oxygen (40%), Sham - Sleep Apnea | Not applicable | Completed | Brigham and Women's Hospital | 47 | 2012-11-01 | 2018-03-20 |
| Intervention Study to Investigate Supplemental Oxygen in COPD Supplemental oxygen - COPD, Physical Activity | Not applicable | Unknown | Uppsala University | 144 | 2012-11-01 | 2022-06-21 |
| Pathogenesis and Outcomes of Sleep Disordered Breathing in Chronic Obstructive Pulmonary Disease (COPD) Oxygen, High flow of room air - COPD | Not applicable | Completed | Johns Hopkins University | 52 | 2012-08-01 | 2016-10-05 |
| Treatment of Sleep Related Breathing Disorders in Patients With Pulmonary Hypertension acetazolamide, Supplemental oxygen, Non-invasive ventilation - Pulmonary Hypertension, Breathing-Related Sleep Disorder | Phase 2 | Completed | University of Zurich | 23 | 2010-11-01 | 2012-12-12 |
| Whole Brain Radiation Therapy With Oxygen, With or Without RSR13, in Women With Brain Metastases From Breast Cancer Efaproxiral, Whole Brain Radiation Therapy (WBRT), Supplemental Oxygen - Breast Cancer, Metastases | Phase 3 | Completed | Spectrum Pharmaceuticals, Inc | 368 | 2004-02-01 | 2013-05-10 |
Sleep Apnea Syndromes (6) · Pulmonary Disease, Chronic Obstructive (3) · Sleep Apnea, Obstructive (3) · Hypoxia (2) · Sleep Wake Disorders (2) · Altitude Sickness (1) · Alzheimer Disease (1) · Anemia, Sickle Cell (1) · Ankylosis (1) · Brain Neoplasms (1) · Breast Neoplasms (1) · Fatigue (1) · Glucose Intolerance (1) · Glucose Metabolism Disorders (1) · Hallux Valgus (1)
Johns Hopkins University (2) · University of California, San Diego (2) · Brigham and Women's Hospital (1) · CES University (1) · Institut für Pneumologie Hagen Ambrock eV (1) · John D. Dingell VA Medical Center (1) · Massachusetts General Hospital (1) · Peking Union Medical College Hospital (1) · Spectrum Pharmaceuticals, Inc (1) · St. Louis University (1) · University of Missouri-Columbia (1) · University of Zurich (1) · Uppsala University (1) · Vyaire Medical (1)
United States (9) · Argentina (1) · Austria (1) · Brazil (1) · Canada (1) · Chile (1) · Colombia (1) · Croatia (1) · France (1) · Germany (1) · Greece (1) · Hungary (1) · Italy (1) · Lithuania (1) · Nepal (1)
Atul Malhotra, MD (1) · Bettina Mittendorfer, PhD (1) · Carin Hagberg, MD (1) · Christer Janson, Professor (1) · Christopher Schmickl (1) · Dong Wu, M.D. (1) · Georg Nilius, MD (1) · Haifeng Xu, M.D. (1) · Hartmut Schneider, M.D., Ph.D. (1) · John Suh, MD (1) · Luu Pham, MD (1) · M Safwan Badr, M.D. (1) · Marta I Berrio, MD (1)
PMID 19293693, PMID 24366914, PMID 24444661, PMID 24991933, PMID 25168304, PMID 25247853, PMID 25761980, PMID 26287299, PMID 30139771, PMID 32651241, PMID 3372436, PMID 35577100, PMID 40135690, PMID 41025403, PMID 6638679
K23HL155730 (1), R01HL090897 (1)