96 completed. 96 Phase 3, 23 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 96 | Completed 96 |
| Phase 2 | 23 | Completed 23 |
Follow Sugars: new trials by email Literature Review of Sugars trials Research Report on Sugars
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating the Combined Effect of Oral Premedications on Inferior Alveolar Nerve Block Effectiveness Patients in this group will receive an oral placebo (e.g., sugar tablet or inert capsule) 1 hour before the IANB, Patients will receive ibuprofen (400-600 mg, standard therapeutic dose) orally, 1 hour prior to IANB, Group III - Serratiopeptidase Group - Symptomatic Irreversible Pulpitis | Phase 3 | Completed | Zahoor khan | 96 | 2023-11-23 | 2025-09-09 |
| Study of LAU-7b for the Treatment of Long COVID in Adults LAU-7b for 3 cycles, LAU-7b for 1 cycle, then placebo, Placebo for 3 cycles - Long COVID | Phase 2 / Phase 3 | Completed | Laurent Pharmaceuticals Inc. | 272 | 2023-11-15 | 2026-01-06 |
| The Role of Trimetazidine on Right Ventricle Function in Pulmonary Arterial Hypertension Trimetazidine, Placebo oral capsule - Precapillary Pulmonary Hypertension | Phase 2 / Phase 3 | Completed | Universitas Indonesia | 26 | 2017-09-10 | 2019-10-03 |
| Aspirin in Young Psychotic Patients Aspirin, Placebo, Pantoprazole - Psychosis, Acute Psychosis | Phase 2 / Phase 3 | Completed | Clinic for Psychiatric Disorders, Dr Laza Lazarevic | 60 | 2017-07-20 | 2024-09-23 |
| Role of Alphacalcidol Supplement to Reduce Pain and COMP in Geriatric Knee Osteoarthritis Patients Alfacalcidol 1 MCG Oral Capsule, Sugar pill - Osteoarthritis, Knee, Aged | Phase 3 | Completed | Syarif Hidayatullah State Islamic University Jakarta | 146 | 2017-07-01 | 2020-05-28 |
| Phase 3 Randomized Placebo Controlled Clinical Trial of Donepezil Donepezil 5 mg, Placebo - Cognitive Dysfunction, Memory Impairment | Phase 3 | Completed | Wake Forest University Health Sciences | 276 | 2017-05-30 | 2023-09-13 |
| Impact of EMpagliflozin on Cardiac Function and Biomarkers of Heart Failure in Patients With Acute MYocardial Infarction Empagliflozin 10 mg, Placebo Oral Tablet - Acute Myocardial Infarction | Phase 3 | Completed | Medical University of Graz | 476 | 2017-05-11 | 2024-08-22 |
| Aripiprazole for Bipolar Disorder and Alcohol Use Disorder Aripiprazole, Placebo - Bipolar Disorder, Alcoholism | Phase 3 | Completed | University of Texas Southwestern Medical Center | 75 | 2016-11-01 | 2024-09-19 |
| Low Dose Oral Methotrexate in Pediatric Crohn's Disease Patients Initiating Anti-Tumor Necrosis Factor (Anti-TNF) Therapy Methotrexate, Sugar pill (placebo) - Pediatric Crohn's Disease | Phase 3 | Completed | University of North Carolina, Chapel Hill | 306 | 2016-10-01 | 2023-04-12 |
| Altitude Sickness Prevention and Efficacy of Comparative Treatments Budesonide, Acetazolamide, Placebo - Acute Mountain Sickness | Phase 3 | Completed | Stanford University | 103 | 2016-08-01 | 2018-12-12 |
| Premedication With Melatonin in Lumbar Medial Branch Block Procedure 2 mg Melatonin, 10mg Melatonin, Placebo - Anxiety | Phase 3 | Completed | United States Naval Medical Center, San Diego | 25 | 2016-07-01 | 2024-05-14 |
| Efficacy of Melatonin in Decreasing the Incidence of Delirium in End of Life Patients Melatonin, Sugar pill - Delirium | Phase 3 | Completed | Fraser Health | 19 | 2016-06-29 | 2021-08-26 |
| Selinexor in Advanced Liposarcoma Selinexor, Placebo - Dedifferentiated Liposarcoma | Phase 2 / Phase 3 | Completed | Karyopharm Therapeutics Inc | 342 | 2016-01-04 | 2023-01-23 |
| Treating Insulin Resistance as a Strategy to Improve Outcome in Refractory Bipolar Disorder Placebo, Metformin - Bipolar Disorder | Phase 3 | Completed | Cynthia Calkin | 50 | 2015-09-01 | 2021-01-13 |
| Study of Nalbuphine HCl ER Tablets in Patients With Prurigo Nodularis nalbuphine HCl ER tablets 90 mg BID, nalbuphine HCl ER tablets 180 mg BID, Placebo tablets BID - Prurigo Nodularis, Nodularis Prurigo | Phase 2 / Phase 3 | Completed | Trevi Therapeutics | 62 | 2015-03-01 | 2025-05-21 |
| Non-steroidal Anti-inflammatory Affect on Kidneys in Endurance Distances Ibuprofen, Placebo - Acute Kidney Injury, Exercise-associated Hyponatremia | Phase 3 | Completed | Stanford University | 91 | 2015-03-01 | 2018-12-12 |
| Rizatriptan for Episodic Dizziness in Vestibular Migraine Rizatriptan, Placebo - Vestibular Migraine, Migrainous Vertigo | Phase 2 / Phase 3 | Completed | Robert W. Baloh | 223 | 2014-12-01 | 2021-11-04 |
| Sulpiride Versus Placebo for Reducting Hot Flushes During Climacteric Sulpiride use, Placebo - Menopausal Syndrome, Hot Flashes | Phase 3 | Completed | Hospital de Clinicas de Porto Alegre | 28 | 2014-06-01 | 2019-01-14 |
| Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus nalbuphine HCl ER tablets 60 mg BID, nalbuphine HCl ER tablets 120mg BID, Placebo tablets BID - Uremic Pruritus, Pruritus | Phase 2 / Phase 3 | Completed | Trevi Therapeutics | 373 | 2014-06-01 | 2025-05-21 |
| BK Virus in Salivary Gland Disease: Treating the Potential Etiologic Agent Ciprofloxacin, Placebo - HIV, Salivary Gland Disease | Phase 3 | Completed | University of North Carolina, Chapel Hill | 17 | 2014-04-01 | 2019-07-11 |
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Alcoholism (5) · Bipolar Disorder (4) · Smoking (4) · Tobacco Use Disorder (4) · Breast Neoplasms (3) · Cardiovascular Diseases (3) · Child Development Disorders, Pervasive (3) · Fatigue (3) · Heart Failure (3) · Hot Flashes (3) · Neoplasms (3) · Obesity (3) · Pain (3) · Phobia, Social (3) · Psychotic Disorders (3)
Indiana University (3) · Lindner Center of HOPE (3) · Mayo Clinic (3) · Bankole Johnson (2) · Federal University of São Paulo (2) · Hospital de Clinicas de Porto Alegre (2) · M.D. Anderson Cancer Center (2) · Massachusetts General Hospital (2) · Noven Therapeutics (2) · OPKO IP Holdings II, Inc. (2) · Stanford University (2) · Trevi Therapeutics (2) · University of North Carolina, Chapel Hill (2) · University of Texas Southwestern Medical Center (2) · Baylor College of Medicine (1)
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Arthur Waldbaum, MD (2) · Cynthia Strout, MD (2) · David J Portman, MD (2) · Derrick R Havin, MD (2) · Donna DeSantis, MD (2) · Eric Ross, MD (2) · Grant S Lipman, MD (2) · Joel Melnick, MD (2) · Marvin Kalafer, MD (2) · Mildred Farmer, MD (2) · Robin Kroll, MD (2) · Sandra Hurtado, MD (2) · Stephen Swanson, MD (2) · Susan L McElroy, MD (2)
PMID 24045678, PMID 24552977, PMID 25137243, PMID 34611902, PMID 37142273, PMID 37230961, PMID 16414336, PMID 17194267, PMID 17668979, PMID 17716312, PMID 17716313, PMID 18174456, PMID 18251624, PMID 18672990, PMID 19155011, PMID 19167733, PMID 19489872, PMID 20151804, PMID 20155590, PMID 20348487, PMID 20580029, PMID 20937388, PMID 21072305, PMID 21357860, PMID 21422479, PMID 21632810, PMID 21677329, PMID 21849262, PMID 22367654, PMID 22870045, PMID 22991405, PMID 23071896, PMID 23205917, PMID 23478662, PMID 23562364, PMID 23649042, PMID 23744513, PMID 23897038, PMID 24057996, PMID 24162898, PMID 24237691, PMID 24326693, PMID 24330893, PMID 24399554, PMID 24569618, PMID 24833648, PMID 24852376, PMID 24986712, PMID 25104521, PMID 25129340
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